The Origin and Biomedical Relevance of Cannabigerol

Short review on the potential alternatives to antibiotics in the era of antibiotic resistance

(2022) Arsene Mbarga Manga Joseph et al.   Journal of Applied Pharmaceutical Science

Review of delta‐8‐tetrahydrocannabinol (Δ 8 ‐THC): Comparative pharmacology with Δ 9 ‐THC

(2022) Michael Tagen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of Rare Phytocannabinoids on the Endocannabinoid System of Human Keratinocytes

(2022) Camilla Di Meo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Development of Water-Soluble Electrospun Fibers for the Oral Delivery of Cannabinoids

(2021) Eleftherios G. Andriotis et al.   AAPS PHARMSCITECH

Cannabis sativa L. as a Natural Drug Meeting the Criteria of a Multitarget Approach to Treatment

(2021) Anna Stasiłowicz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Three novel transcription factors involved in cannabinoid biosynthesis in Cannabis sativa L.

(2021) Yuanyuan Liu et al.   PLANT MOLECULAR BIOLOGY

Cannabigerol Is a Potential Therapeutic Agent in a Novel Combined Therapy for Glioblastoma

(2021) Tamara T. Lah et al.   Cells

Cancer Initiation, Progression and Resistance: Are Phytocannabinoids from Cannabis sativa L. Promising Compounds?

(2021) Ersilia Nigro et al.   MOLECULES

Detectability of cannabinoids in the serum samples of cannabis users: Indicators of recent cannabis use? A follow‐up study

(2021) Michael Krämer et al.   Drug Testing and Analysis

CBG, CBD, Δ9-THC, CBN, CBGA, CBDA and Δ9-THCA as antioxidant agents and their intervention abilities in antioxidant action

(2021) Andrzej L. Dawidowicz et al.   FITOTERAPIA

Chemical composition and antioxidant potential of Cannabis sativa L. roots

(2021) Christoph Kornpointner et al.   INDUSTRIAL CROPS AND PRODUCTS

The anti-inflammatory effects of cannabidiol and cannabigerol alone, and in combination

(2021) Carmen Lorena Robaina Cabrera et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses

(2021) Kenneth B. Walsh et al.   Frontiers in Pharmacology

Major Phytocannabinoids and Their Related Compounds: Should We Only Search for Drugs That Act on Cannabinoid Receptors?

(2021) Leontina Elena Filipiuc et al.   Pharmaceutics

Cannabis sativa

(2020) Susanne Schilling et al.   CURRENT BIOLOGY

Antioxidant and Neuroprotective Effects Induced by Cannabidiol and Cannabigerol in Rat CTX-TNA2 Astrocytes and Isolated Cortexes

(2020) Viviana di Giacomo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Systematic Review of Minor Phytocannabinoids with Promising Neuroprotective Potential

(2020) Nicole L. Stone et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Comparative In Vitro Study of the Neuroprotective Effect Induced by Cannabidiol, Cannabigerol, and Their Respective Acid Forms: Relevance of the 5-HT1A Receptors

(2020) Carolina Echeverry et al.   NEUROTOXICITY RESEARCH

Neuroprotection with the cannabigerol quinone derivative VCE-003.2 and its analogs CBGA-Q and CBGA-Q-Salt in Parkinson's disease using 6-hydroxydopamine-lesioned mice

(2020) Sonia Burgaz et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa

(2020) Ayat Zagzoog et al.   Scientific Reports

A systematic review of phytocannabinoid exposure on the endocannabinoid system: Implications for psychosis

(2019) Maya R. Jacobson et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Identification and characterization of phytocannabinoids as novel dual PPARα/γ agonists by a computational and in vitro experimental approach

(2019) Enrico D'Aniello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Diverse TRPV1 responses to cannabinoids.

(2019) J. Starkus et al.   Channels

Medicinal plants and bioactive natural compounds for cancer treatment: Important advances for drug discovery

(2019) Fernanda Majolo et al.   Phytochemistry Letters

Antioxidative and Anti-Inflammatory Properties of Cannabidiol

(2019) Sinemyiz Atalay et al.   Antioxidants

In Vitro Model of Neuroinflammation: Efficacy of Cannabigerol, a Non-Psychoactive Cannabinoid

(2018) Agnese Gugliandolo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson’s disease: possible involvement of different binding sites at the PPARγ receptor

(2018) Concepción García et al.   Journal of Neuroinflammation

Structure-Activity Relationship of Cannabis Derived Compounds for the Treatment of Neuronal Activity-Related Diseases

(2018) Cristina Prandi et al.   MOLECULES

Brazilian medicinal plants with corroborated anti-inflammatory activities: a review

(2018) Victor Pena Ribeiro et al.   PHARMACEUTICAL BIOLOGY

Current Perspectives on Biotechnological Cannabinoid Production in Plants

(2018) Julia Schachtsiek et al.   PLANTA MEDICA

Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1–CB2 Heteroreceptor Complexes

(2018) Gemma Navarro et al.   Frontiers in Pharmacology

Neuroprotective effects of the cannabigerol quinone derivative VCE-003.2 in SOD1 G93A transgenic mice, an experimental model of amyotrophic lateral sclerosis

(2018) Carmen Rodríguez-Cueto et al.   BIOCHEMICAL PHARMACOLOGY

Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history

(2018) Sara Anna Bonini et al.   JOURNAL OF ETHNOPHARMACOLOGY

Interplay between chemistry and morphology in medical cannabis (Cannabis sativa L.)

(2018) Nirit Bernstein et al.   INDUSTRIAL CROPS AND PRODUCTS

Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

(2017) Sabrina Giacoppo et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Terpene synthases from Cannabis sativa

(2017) Judith K. Booth et al.   PLoS One

An Atmospheric Pressure Chemical Ionization MS/MS Assay Using Online Extraction for the Analysis of 11 Cannabinoids and Metabolites in Human Plasma and Urine

(2017) Jelena Klawitter et al.   THERAPEUTIC DRUG MONITORING

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol

(2017) Paula Morales et al.   Frontiers in Pharmacology

Simultaneous quantification of 11 cannabinoids and metabolites in human urine by liquid chromatography tandem mass spectrometry using WAX-S tips

(2016) Maria Andersson et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Free and Glucuronide Whole Blood Cannabinoids' Pharmacokinetics after Controlled Smoked, Vaporized, and Oral Cannabis Administration in Frequent and Occasional Cannabis Users: Identification of Recent Cannabis Intake

(2016) M. N. Newmeyer et al.   CLINICAL CHEMISTRY

Cannabinoid disposition in oral fluid after controlled smoked, vaporized, and oral cannabis administration

(2016) Madeleine J. Swortwood et al.   Drug Testing and Analysis

VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington’s disease

(2016) Javier Díaz-Alonso et al.   Scientific Reports

Cannabis sativa: The Plant of the Thousand and One Molecules

(2016) Christelle M. Andre et al.   Frontiers in Plant Science

The Endocannabinoid System and its Modulation by Phytocannabinoids

(2015) Vincenzo Di Marzo et al.   Neurotherapeutics

Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid

(2014) Francesca Borrelli et al.   CARCINOGENESIS

A Cannabigerol Derivative Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis

(2014) Francisco J. Carrillo-Salinas et al.   PLoS One

Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease

(2013) Francesca Borrelli et al.   BIOCHEMICAL PHARMACOLOGY

A Cannabigerol Quinone Alleviates Neuroinflammation in a Chronic Model of Multiple Sclerosis

(2012) Aitor G. Granja et al.   Journal of Neuroimmune Pharmacology

COX-2 and PPAR-  Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells

(2012) R. Ramer et al.   MOLECULAR CANCER THERAPEUTICS

Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides

(2012) S. J. Gagne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa

(2011) Lucia Renee Ruhaak et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Phytocannabinoids as novel therapeutic agents in CNS disorders

(2011) Andrew J. Hill et al.   PHARMACOLOGY & THERAPEUTICS

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive–compulsive behaviour

(2011) Serena Deiana et al.   PSYCHOPHARMACOLOGY

Effects of cannabinoids and cannabinoid-enrichedCannabisextracts on TRP channels and endocannabinoid metabolic enzymes

(2010) Luciano De Petrocellis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Solubility of non-psychoactive cannabinoids in supercritical carbon dioxide and comparison with psychoactive cannabinoids

(2010) Helene Perrotin-Brunel et al.   JOURNAL OF SUPERCRITICAL FLUIDS

Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist

(2009) MG Cascio et al.   BRITISH JOURNAL OF PHARMACOLOGY

Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway

(2009) Futoshi Taura et al.   FEBS LETTERS