Iron increases lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the HIF1α-PPARγ pathway

Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway

(2022) Guang-Hui Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipid overload impairs hepatic VLDL secretion via oxidative stress-mediated PKCδ-HNF4α-MTP pathway in large yellow croaker (Larimichthys crocea)

(2021) Wei Fang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Iron overload in the motor cortex induces neuronal ferroptosis following spinal cord injury

(2021) Zhou Feng et al.   Redox Biology

Copper (Cu) induced changes of lipid metabolism through oxidative stress-mediated autophagy and Nrf2/PPARγ pathways

(2021) Chong-Chao Zhong et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A SUMOylation-dependent HIF-1α/CLDN6 negative feedback mitigates hypoxia-induced breast cancer metastasis

(2020) Yiyang Jia et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Regulation of intestinal lipid metabolism: current concepts and relevance to disease

(2020) Chih-Wei Ko et al.   Nature Reviews Gastroenterology & Hepatology

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond

(2020) Pearl Lee et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Menopause-Associated Lipid Metabolic Disorders and Foods Beneficial for Postmenopausal Women

(2020) Seong-Hee Ko et al.   Nutrients

Basics and principles of cellular and systemic iron homeostasis

(2020) Angeliki Katsarou et al.   MOLECULAR ASPECTS OF MEDICINE

Endoplasmic Reticulum Stress–Mediated Autophagy and Apoptosis Alleviate Dietary Fat–Induced Triglyceride Accumulation in the Intestine and in Isolated Intestinal Epithelial Cells of Yellow Catfish

(2019) Shi-Cheng Ling et al.   JOURNAL OF NUTRITION

Lipophagy mediated carbohydrate-induced changes of lipid metabolism via oxidative stress, endoplasmic reticulum (ER) stress and ChREBP/PPARγ pathways

(2019) Tao Zhao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nuclear Factor E2-Related Factor 2 Mediates Oxidative Stress-Induced Lipid Accumulation in Adipocytes by Increasing Adipogenesis and Decreasing Lipolysis

(2019) Xudong Sun et al.   ANTIOXIDANTS & REDOX SIGNALING

The effects of iron overload on mitochondrial function, mitochondrial dynamics, and ferroptosis in cardiomyocytes

(2019) Natticha Sumneang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Iron homeostasis and oxidative stress: An intimate relationship

(2019) Dimitrios Galaris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Oxidative stress and mitochondrial dysfunction mediated Cd-induced hepatic lipid accumulation in zebrafish Danio rerio

(2018) Ya-Xiong Pan et al.   AQUATIC TOXICOLOGY

Lipotoxicity and the gut-liver axis in NASH pathogenesis

(2018) Fabio Marra et al.   JOURNAL OF HEPATOLOGY

Functional Analysis of Promoters of Genes in Lipid Metabolism and Their Transcriptional Response to STAT3 under Leptin Signals

(2018) Kun Wu et al.   Genes

Zn Stimulates the Phospholipids Biosynthesis via the Pathways of Oxidative and Endoplasmic Reticulum Stress in the Intestine of Freshwater Teleost Yellow Catfish

(2018) Kun Wu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Inhibitory Effect of Astaxanthin on Oxidative Stress-Induced Mitochondrial Dysfunction-A Mini-Review

(2018) Suhn Kim et al.   Nutrients

Inflammation and Hypoxia: HIF and PHD Isoform Selectivity

(2018) Emily R. Watts et al.   TRENDS IN MOLECULAR MEDICINE

Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice

(2017) Juthamas Khamseekaew et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity

(2017) Dawei Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

(2017) Weinan Du et al.   Nature Communications

Fatty acid metabolism in fish species as a biomarker for environmental monitoring

(2016) Hugo F. Olivares-Rubio et al.   ENVIRONMENTAL POLLUTION

Lack of mitochondrial DNA impairs chemical hypoxia-induced autophagy in liver tumor cells through ROS-AMPK-ULK1 signaling dysregulation independently of HIF-1α

(2016) Jose J.G. Marin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment

(2016) Meric Erikci Ertunc et al.   JOURNAL OF LIPID RESEARCH

Hypoxic control of metastasis

(2016) E. B. Rankin et al.   SCIENCE

The iron chelator deferasirox affects redox signalling in haematopoietic stem/progenitor cells

(2015) Tiziana Tataranni et al.   BRITISH JOURNAL OF HAEMATOLOGY

SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis

(2015) Supak Jenkitkasemwong et al.   Cell Metabolism

An iron-regulated and glycosylation-dependent proteasomal degradation pathway for the plasma membrane metal transporter ZIP14

(2014) N. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia induces peroxisome proliferator-activated receptor γ expression via HIF-1-dependent mechanisms in HepG2 cell line

(2013) Ying-Ze Zhao et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders

(2013) H. Nam et al.   HAEMATOLOGICA

Effects of excess dietary iron and fat on glucose and lipid metabolism

(2013) Joo Sun Choi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Systemic Iron Homeostasis

(2013) Tomas Ganz   PHYSIOLOGICAL REVIEWS

Intestinal iron absorption

(2012) Brie K. Fuqua et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Interactions between hepatic iron and lipid metabolism with possible relevance to steatohepatitis

(2012) Umbreen Ahmed   WORLD JOURNAL OF GASTROENTEROLOGY

Regulation of cellular iron metabolism

(2011) Jian Wang et al.   BIOCHEMICAL JOURNAL

Coordinate expression and localization of iron and zinc transporters explain iron–zinc interactions during uptake in Caco-2 cells: implications for iron uptake at the enterocyte

(2011) Vasuprada Iyengar et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Activation of a HIF1α-PPARγ Axis Underlies the Integration of Glycolytic and Lipid Anabolic Pathways in Pathologic Cardiac Hypertrophy

(2009) Jaya Krishnan et al.   Cell Metabolism

Fatty Acid Synthase Gene Is Up-regulated by Hypoxia via Activation of Akt and Sterol Regulatory Element Binding Protein-1

(2008) E. Furuta et al.   CANCER RESEARCH

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL