Lipid overload impairs hepatic VLDL secretion via oxidative stress-mediated PKCδ-HNF4α-MTP pathway in large yellow croaker (Larimichthys crocea)

Diallyl Trisulfide (DATS) Suppresses AGE-Induced Cardiomyocyte Apoptosis by Targeting ROS-Mediated PKCδ Activation

(2020) Dennis Jine-Yuan Hsieh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chrysin ameliorates hepatic steatosis induced by a diet deficient in methionine and choline by inducing the secretion of hepatocyte nuclear factor 4α-dependent very low-density lipoprotein

(2020) Yu Song et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

2,3,5,4'-tetrahydroxystilbence-2-O-β-D-glucoside attenuates hepatic steatosis via IKKβ/NF-κB and Keap1-Nrf2 pathways in larval zebrafish

(2020) Cheng Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Activation of the Farnesoid X Receptor (FXR) Suppresses Linoleic Acid-Induced Inflammation in the Large Yellow Croaker (Larimichthys crocea)

(2020) Jianlong Du et al.   JOURNAL OF NUTRITION

ω-6 Polyunsaturated fatty acids (linoleic acid) activate both autophagy and antioxidation in a synergistic feedback loop via TOR-dependent and TOR-independent signaling pathways

(2020) Bo Yang et al.   Cell Death & Disease

Lipophagy mediated carbohydrate-induced changes of lipid metabolism via oxidative stress, endoplasmic reticulum (ER) stress and ChREBP/PPARγ pathways

(2019) Tao Zhao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats

(2019) Xue Wu et al.   Frontiers in Pharmacology

Macrophages in Zebrafish Models of Liver Diseases

(2019) Arkadi Shwartz et al.   Frontiers in Immunology

High fat diet-induced oxidative stress blocks hepatocyte nuclear factor 4α and leads to hepatic steatosis in mice

(2018) Dongsheng Yu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis

(2018) Yan Liu et al.   Nature Communications

High-fat diet induces aberrant hepatic lipid secretion in blunt snout bream by activating endoplasmic reticulum stress-associated IRE1/XBP1 pathway

(2018) Xiu-Fei Cao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lomitapide for the treatment of hypercholesterolemia

(2017) Amanda J. Berberich et al.   EXPERT OPINION ON PHARMACOTHERAPY

High-fat diet induces skeletal muscle oxidative stress in a fiber type-dependent manner in rats

(2017) Ricardo A. Pinho et al.   FREE RADICAL BIOLOGY AND MEDICINE

Functional characterization and differential nutritional regulation of putative Elovl5 and Elovl4 elongases in large yellow croaker (Larimichthys crocea)

(2017) Songlin Li et al.   Scientific Reports

Dietary lipid concentration affects liver mitochondrial DNA copy number, gene expression and DNA methylation in large yellow croaker (Larimichthys crocea)

(2016) Kai Liao et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Dihydromyricetin ameliorates oleic acid-induced lipid accumulation in L02 and HepG2 cells by inhibiting lipogenesis and oxidative stress

(2016) Caifeng Xie et al.   LIFE SCIENCES

Dietary Olive and Perilla Oils Affect Liver Mitochondrial DNA Methylation in Large Yellow Croakers

(2015) Kai Liao et al.   JOURNAL OF NUTRITION

A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism

(2015) Yang Xu et al.   Nature Communications

Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets?

(2014) Isabelle Côté et al.   BRITISH JOURNAL OF NUTRITION

Activation of the Nrf2-ARE Pathway in Hepatocytes Protects Against Steatosis in Nutritionally Induced Non-alcoholic Steatohepatitis in Mice

(2014) Lung-Yi Lee et al.   TOXICOLOGICAL SCIENCES

NADPH Oxidases: A Perspective on Reactive Oxygen Species Production in Tumor Biology

(2013) Jennifer L. Meitzler et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative stress and vascular inflammation in aging

(2013) Mariam El Assar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Achieving the Balance between ROS and Antioxidants: When to Use the Synthetic Antioxidants

(2013) Borut Poljsak et al.   Oxidative Medicine and Cellular Longevity

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

(2012) Marina Cuchel et al.   LANCET

Protein-sparing effect of dietary lipid in practical diets for blunt snout bream (Megalobrama amblycephala) fingerlings: effects on digestive and metabolic responses

(2011) Xiangfei Li et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Different fatty acids inhibit apoB100 secretion by different pathways: unique roles for ER stress, ceramide, and autophagy

(2011) Jorge Matias Caviglia et al.   JOURNAL OF LIPID RESEARCH

The Hepatitis E Virus ORF3 Protein Regulates the Expression of Liver-Specific Genes by Modulating Localization of Hepatocyte Nuclear Factor 4

(2011) Vivek Chandra et al.   PLoS One

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

The ERK1/2-Hepatocyte Nuclear Factor 4α Axis Regulates HumanABCC6Gene Expression in Hepatocytes

(2010) Hugues de Boussac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Berberine reduces methylation of theMTTPpromoter and alleviates fatty liver induced by a high-fat diet in rats

(2010) XinXia Chang et al.   JOURNAL OF LIPID RESEARCH

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

(2008) Tsuguhito Ota et al.   JOURNAL OF CLINICAL INVESTIGATION

NF-E2-Related Factor 2 Inhibits Lipid Accumulation and Oxidative Stress in Mice Fed a High-Fat Diet

(2008) Y. Tanaka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Lipoic acid prevents high-fat diet–induced dyslipidemia and oxidative stress: A microarray analysis

(2008) Rui-li Yang et al.   NUTRITION