Replication stress impairs chromosome segregation and preimplantation development in human embryos
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Title
Replication stress impairs chromosome segregation and preimplantation development in human embryos
Authors
Keywords
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Journal
CELL
Volume 185, Issue 16, Pages 2988-3007.e20
Publisher
Elsevier BV
Online
2022-07-19
DOI
10.1016/j.cell.2022.06.028
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Note: Only part of the references are listed.- DNA replication fork speed underlies cell fate changes and promotes reprogramming
- (2022) Tsunetoshi Nakatani et al. NATURE GENETICS
- DNA replication is highly resilient and persistent under the challenge of mild replication stress
- (2022) Camelia Mocanu et al. Cell Reports
- The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing
- (2021) Rachel E. Rodin et al. NATURE NEUROSCIENCE
- Inherent mosaicism and extensive mutation of human placentas
- (2021) Tim H. H. Coorens et al. NATURE
- Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions
- (2021) Luca Orlando et al. Cell Reports
- Twelve years of SAMtools and BCFtools
- (2021) Petr Danecek et al. GigaScience
- Parental genome unification is highly error-prone in mammalian embryos
- (2021) Tommaso Cavazza et al. CELL
- Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability
- (2020) Meiyan Wang et al. Cell Stem Cell
- Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
- (2020) Amaia Ercilla et al. Cell Reports
- Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos
- (2020) Laura Girardi et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genome-wide high-resolution mapping of mitotic DNA synthesis sites and common fragile sites by direct sequencing
- (2020) Fang Ji et al. CELL RESEARCH
- High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing
- (2020) Morgane Macheret et al. CELL RESEARCH
- New insights into abasic site repair and tolerance
- (2020) Petria S. Thompson et al. DNA REPAIR
- 3D genome organization contributes to genome instability at fragile sites
- (2020) Dan Sarni et al. Nature Communications
- Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos
- (2020) Michael V. Zuccaro et al. CELL
- PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts
- (2020) Ann Liza Piberger et al. Nature Communications
- Constitutional 763.3 Kb chromosome 1q43 duplication encompassing only CHRM3 gene identified by next generation sequencing (NGS) in a child with intellectual disability
- (2019) Xiaofei Cheng et al. Molecular Cytogenetics
- Segmental aneuploidy in human blastocysts: a qualitative and quantitative overview
- (2019) María-José Escribà et al. Reproductive Biology and Endocrinology
- Chromosome errors in human eggs shape natural fertility over reproductive life span
- (2019) Jennifer R. Gruhn et al. SCIENCE
- Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide
- (2019) Olivier Brison et al. Nature Communications
- Low estradiol responses in oocyte donors undergoing gonadotropin stimulation do not influence clinical outcomes
- (2018) Katherine L. Palmerola et al. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes
- (2018) L. Zakarin Safier et al. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- Computational correction of index switching in multiplexed sequencing libraries
- (2018) Anton J M Larsson et al. NATURE METHODS
- High speed of fork progression induces DNA replication stress and genomic instability
- (2018) Apolinar Maya-Mendoza et al. NATURE
- Prevalence and authenticity of de-novo segmental aneuploidy (>16 Mb) in human blastocysts as detected by next-generation sequencing
- (2018) Shuang Zhou et al. REPRODUCTIVE BIOMEDICINE ONLINE
- The incidence and origin of segmental aneuploidy in human oocytes and preimplantation embryos
- (2017) D Babariya et al. HUMAN REPRODUCTION
- Focused time-lapse analysis reveals novel aspects of human fertilization and suggests new parameters of embryo viability
- (2017) G Coticchio et al. HUMAN REPRODUCTION
- Somatic mutations reveal asymmetric cellular dynamics in the early human embryo
- (2017) Young Seok Ju et al. NATURE
- Genomic instability during reprogramming by nuclear transfer is DNA replication dependent
- (2017) Gloryn Chia et al. NATURE CELL BIOLOGY
- BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination
- (2017) Weiran Feng et al. Nature Communications
- Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA
- (2017) Divya Ramalingam Iyer et al. PLoS Genetics
- Possible genes responsible for developmental delay observed in patients with rare 2q23q24 microdeletion syndrome: Literature review and description of an additional patient
- (2017) Keiko Shimojima et al. CONGENITAL ANOMALIES
- Genome Transfer Prevents Fragmentation and Restores Developmental Potential of Developmentally Compromised Postovulatory Aged Mouse Oocytes
- (2017) Mitsutoshi Yamada et al. Stem Cell Reports
- Tripolar mitosis and partitioning of the genome arrests human preimplantation development in vitro
- (2017) Christian S. Ottolini et al. Scientific Reports
- Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells
- (2016) Pei-Chi Wei et al. CELL
- A Mechanism for Controlled Breakage of Under-replicated Chromosomes during Mitosis
- (2016) Heike Duda et al. DEVELOPMENTAL CELL
- Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells
- (2016) Alberto Moreno et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells
- (2016) Akshay K. Ahuja et al. Nature Communications
- Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential
- (2016) Helen Bolton et al. Nature Communications
- Optimizing sparse sequencing of single cells for highly multiplex copy number profiling
- (2015) Timour Baslan et al. GENOME RESEARCH
- Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells
- (2015) Ralph Zellweger et al. JOURNAL OF CELL BIOLOGY
- A clinically useful simplified blastocyst grading system
- (2015) Alison Richardson et al. REPRODUCTIVE BIOMEDICINE ONLINE
- Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis
- (2015) Maria Vera-Rodriguez et al. Nature Communications
- Large transcription units unify copy number variants and common fragile sites arising under replication stress
- (2014) Thomas E. Wilson et al. GENOME RESEARCH
- DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assembly
- (2014) Ilari Scheinin et al. GENOME RESEARCH
- The DNA methylation landscape of human early embryos
- (2014) Hongshan Guo et al. NATURE
- Interstitial 7q31.1 copy number variations disrupting IMMP2L gene are associated with a wide spectrum of neurodevelopmental disorders
- (2014) Stefania Gimelli et al. Molecular Cytogenetics
- Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer
- (2013) Masahito Tachibana et al. CELL
- How unfinished business from S-phase affects mitosis and beyond
- (2013) Hocine W Mankouri et al. EMBO JOURNAL
- The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening
- (2013) Jason M. Franasiak et al. FERTILITY AND STERILITY
- Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitor
- (2013) Constance King et al. INVESTIGATIONAL NEW DRUGS
- DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
- (2013) Atsushi Shibata et al. MOLECULAR CELL
- Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing
- (2013) Zhigang Xue et al. NATURE
- Replication stress links structural and numerical cancer chromosomal instability
- (2013) Rebecca A. Burrell et al. NATURE
- Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells
- (2013) Liying Yan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells
- (2013) T. Wilhelm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The human first cell cycle: impact on implantation
- (2013) Jesús Aguilar et al. REPRODUCTIVE BIOMEDICINE ONLINE
- Cleavage speed and implantation potential of early-cleavage embryos in IVF or ICSI cycles
- (2012) Meng-Ju Lee et al. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- DNA breaks and chromosome pulverization from errors in mitosis
- (2012) Karen Crasta et al. NATURE
- Genome-wide copy number analysis of single cells
- (2012) Timour Baslan et al. Nature Protocols
- Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress
- (2012) S. Liu et al. NUCLEIC ACIDS RESEARCH
- Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage
- (2012) Shawn L. Chavez et al. Nature Communications
- Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
- (2011) Assaf C. Bester et al. CELL
- Factors determining DNA double-strand break repair pathway choice in G2 phase
- (2011) Atsushi Shibata et al. EMBO JOURNAL
- De novo 911 Kb interstitial deletion on chromosome 1q43 in a boy with mental retardation and short stature
- (2011) M.D. Perrone et al. European Journal of Medical Genetics
- Replication stress induces 53BP1-containing OPT domains in G1 cells
- (2011) Jeanine A. Harrigan et al. JOURNAL OF CELL BIOLOGY
- Discovery of Potent and Selective Inhibitors of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Protein Kinase as Potential Anticancer Agents
- (2011) Jean-Damien Charrier et al. JOURNAL OF MEDICINAL CHEMISTRY
- Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes
- (2011) Anne Helmrich et al. MOLECULAR CELL
- Tumour evolution inferred by single-cell sequencing
- (2011) Nicholas Navin et al. NATURE
- Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site
- (2011) Anne Letessier et al. NATURE
- 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
- (2011) Claudia Lukas et al. NATURE CELL BIOLOGY
- DNA-PK-Dependent RPA2 Hyperphosphorylation Facilitates DNA Repair and Suppresses Sister Chromatid Exchange
- (2011) Hungjiun Liaw et al. PLoS One
- Reprogramming within hours following nuclear transfer into mouse but not human zygotes
- (2011) Dieter Egli et al. Nature Communications
- Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome
- (2011) Toshiyuki Bohgaki et al. PLoS Genetics
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- Effect of Trichostatin A on Chromatin Remodeling, Histone Modifications, DNA Replication, and Transcriptional Activity in Cloned Mouse Embryos1
- (2010) Hong-Thuy Bui et al. BIOLOGY OF REPRODUCTION
- Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes
- (2010) Mark Wossidlo et al. EMBO JOURNAL
- Standardization of grading embryo morphology
- (2010) Catherine Racowsky et al. FERTILITY AND STERILITY
- Sperm DNA damage measured by the alkaline Comet assay as an independent predictor of male infertility and in vitro fertilization success
- (2010) Luke Simon et al. FERTILITY AND STERILITY
- Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species
- (2010) D. Xie et al. GENOME RESEARCH
- Genome-wide microarray evidence that 8-cell human blastomeres over-express cell cycle drivers and under-express checkpoints
- (2010) Ann A. Kiessling et al. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair
- (2010) Eva Petermann et al. MOLECULAR CELL
- Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage
- (2010) Connie C Wong et al. NATURE BIOTECHNOLOGY
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
- (2009) Carsten Doil et al. CELL
- Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress
- (2009) V. M. Vassin et al. JOURNAL OF CELL SCIENCE
- Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents
- (2009) H. Hirai et al. MOLECULAR CANCER THERAPEUTICS
- Chromosome instability is common in human cleavage-stage embryos
- (2009) Evelyne Vanneste et al. NATURE MEDICINE
- AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies
- (2008) S. D. Zabludoff et al. MOLECULAR CANCER THERAPEUTICS
- A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex
- (2008) Aude Dupré et al. Nature Chemical Biology
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