Behçet’s disease risk-variant HLA-B51/ERAP1-Hap10 alters human CD8 T cell immunity

Behçet’s disease risk-variant HLA-B51/ERAP1-Hap10 alters human CD8 T cell immunity

(2022) Ann Cavers et al.   ANNALS OF THE RHEUMATIC DISEASES

Common allotypes of ER aminopeptidase 1 have substrate-dependent and highly variable enzymatic properties

(2021) Jonathan P. Hutchinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine

(2021) Valerie Oberhardt et al.   NATURE

Identification of an Unconventional Subpeptidome Bound to the Behçet's Disease-associated HLA-B*51:01 that is Regulated by Endoplasmic Reticulum Aminopeptidase 1 (ERAP1)

(2020) Liye Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

(2019) Tom Dudding et al.   Nature Communications

Redundancy and Complementarity between ERAP1 and ERAP2 Revealed by their Effects on the Behçet’s Disease-Associated HLA-B*51 Peptidome.

(2019) Pablo Guasp et al.   MOLECULAR & CELLULAR PROTEOMICS

Modulation of human Th17 cell responses through complement receptor 3 (CD11 b/CD18) ligation on monocyte-derived dendritic cells

(2018) Johannes Nowatzky et al.   JOURNAL OF AUTOIMMUNITY

Characterization of 108 Genomic DNA Reference Materials for 11 Human Leukocyte Antigen Loci

(2018) Maria P. Bettinotti et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

OMIP-0XX identification, classification, and isolation of major FoxP3 expressing human CD4+ Treg subsets

(2018) Johannes Nowatzky et al.   CYTOMETRY PART A

The Behçet's disease-associated variant of the aminopeptidase ERAP1 shapes a low-affinity HLA-B*51 peptidome by differential subpeptidome processing

(2017) Pablo Guasp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Human Leukocyte Antigen (HLA)-B27 Peptidomein Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion

(2017) Eilon Barnea et al.   MOLECULAR & CELLULAR PROTEOMICS

A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

(2017) Marta Łuksza et al.   NATURE

A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers

(2016) Masaki Takeuchi et al.   ANNALS OF THE RHEUMATIC DISEASES

The Peptidome of Behçet's Disease-Associated HLA-B*51:01 Includes Two Subpeptidomes Differentially Shaped by Endoplasmic Reticulum Aminopeptidase 1

(2016) Pablo Guasp et al.   Arthritis & Rheumatology

HLA-B27

(2015) Paul Bowness   Annual Review of Immunology

Effects of polymorphic variation on the mechanism of Endoplasmic Reticulum Aminopeptidase 1

(2015) Athanasios Stamogiannos et al.   MOLECULAR IMMUNOLOGY

'MHC-I-opathy'—unified concept for spondyloarthritis and Behçet disease

(2015) Dennis McGonagle et al.   Nature Reviews Rheumatology

HLA-B*51 the primary risk in Behcet disease

(2014) G. R. Wallace   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Behcet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity

(2014) M. J. Ombrello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functionally distinctERAP1allotype combinations distinguish individuals with Ankylosing Spondylitis

(2014) Emma Reeves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vascular involvement in Behçet’s syndrome: a retrospective analysis of associations and the time course

(2014) Koray Tascilar et al.   RHEUMATOLOGY

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

(2013) Yohei Kirino et al.   NATURE GENETICS

Immunopathogenic characterization of cutaneous inflammation in Behçet’s disease

(2012) S. Cho et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Granulysin-producing cytotoxic T cells in the mucocutaneous lesions of Behçet disease: a distinct inflammatory response from erythema nodosum

(2011) O. Yamasaki et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

CD8+ CD28− and CD8+ CD57+ T cells and their role in health and disease

(2011) Marius Strioga et al.   IMMUNOLOGY

Cutting Edge: Coding Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 Can Affect Antigenic Peptide Generation In Vitro by Influencing Basic Enzymatic Properties of the Enzyme

(2011) I. Evnouchidou et al.   JOURNAL OF IMMUNOLOGY

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

Immunohistology of skin pathergy reaction in Behçet's disease

(2010) A. GÜL et al.   BRITISH JOURNAL OF DERMATOLOGY

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci

(2010) Nobuhisa Mizuki et al.   NATURE GENETICS

Genome-wide association study identifies variants in the MHC class I, IL10 and IL23R-IL12RB2 regions associated with Behçet's disease

(2010) Elaine F Remmers et al.   NATURE GENETICS

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

(2010) Amy Strange et al.   NATURE GENETICS