Semiconducting Polymer Nanoparticles with Surface‐Mimicking Protein Secondary Structure as Lysosome‐Targeting Chimaeras for Self‐Synergistic Cancer Immunotherapy

Strategies in boosting photosensitization for biomedical applications

(2022) Ming Chen et al.   Science China-Chemistry

Supramolecular Assembled Programmable Nanomedicine As In Situ Cancer Vaccine for Cancer Immunotherapy

(2021) Yu Zhang et al.   ADVANCED MATERIALS

A Supramolecular “Trident” for Cancer Immunotherapy

(2021) Xinxin Li et al.   ADVANCED FUNCTIONAL MATERIALS

Supramolecular Nanofibrils Formed by Coassembly of Clinically Approved Drugs for Tumor Photothermal Immunotherapy

(2021) Shukun Li et al.   ADVANCED MATERIALS

Expansion Microscopy with Multifunctional Polymer Dots

(2021) Jie Liu et al.   ADVANCED MATERIALS

Supramolecular Self‐Assembly‐Facilitated Aggregation of Tumor‐Specific Transmembrane Receptors for Signaling Activation and Converting Immunologically Cold to Hot Tumors

(2021) Jun Li et al.   ADVANCED MATERIALS

Enhancing anti‐PD‐1 immunotherapy by nanomicelles self‐assembled from aptamer‐multivalent‐drug conjugates

(2021) Zhongmin Geng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

(2021) Chi Zhang et al.   Nature Communications

The evolution of commercial drug delivery technologies

(2021) Ava M. Vargason et al.   Nature Biomedical Engineering

Recent Advances in Engineered Materials for Immunotherapy‐Involved Combination Cancer Therapy

(2021) Jun‐Long Liang et al.   ADVANCED MATERIALS

Acidity‐Activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer

(2021) Rundi Song et al.   ADVANCED MATERIALS

A Biomimetic Aggregation‐Induced Emission Photosensitizer with Antigen‐Presenting and Hitchhiking Function for Lipid Droplet Targeted Photodynamic Immunotherapy

(2021) Xiuli Xu et al.   ADVANCED MATERIALS

Boosting Photoacoustic Effect via Intramolecular Motions Amplifying Thermal‐to‐Acoustic Conversion Efficiency for Adaptive Image‐Guided Cancer Surgery

(2021) Heqi Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor‐Microenvironment‐Activatable Polymer Nano‐Immunomodulator for Precision Cancer Photoimmunotherapy

(2021) Jing Liu et al.   ADVANCED MATERIALS

Tumor‐Microenvironment‐Activated Reactive Oxygen Species Amplifier for Enzymatic Cascade Cancer Starvation/Chemodynamic /Immunotherapy

(2021) Man Wang et al.   ADVANCED MATERIALS

Targeted Enrichment of Enzyme‐Instructed Assemblies in Cancer Cell Lysosomes Turns Immunologically Cold Tumors Hot

(2021) Shenglu Ji et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Large π-extended donor-acceptor polymers for highly efficient in vivo near-infrared photoacoustic imaging and photothermal tumor therapy

(2021) Jiangao Li et al.   Science China-Chemistry

Inhibition of Immunosuppressive Tumors by Polymer‐Assisted Inductions of Immunogenic Cell Death and Multivalent PD‐L1 Crosslinking

(2020) Lian Li et al.   ADVANCED FUNCTIONAL MATERIALS

NIR Light‐Driving Barrier‐Free Group Rotation in Nanoparticles with an 88.3% Photothermal Conversion Efficiency for Photothermal Therapy

(2020) Dongmei Xi et al.   ADVANCED MATERIALS

AIE conjugated polymer with ultra-strong ROS generation ability and great biosafety for efficient therapy of bacterial infection

(2020) Taotao Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy

(2020) Hongzhang Deng et al.   NANO LETTERS

Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo

(2020) Lu Zhang et al.   Nature Nanotechnology

Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses

(2020) Yu Chao et al.   Science Advances

Immune-related adverse events of checkpoint inhibitors

(2020) Manuel Ramos-Casals et al.   Nature Reviews Disease Primers

Bioinorganic hybrid bacteriophage for modulation of intestinal microbiota to remodel tumor-immune microenvironment against colorectal cancer

(2020) Xue Dong et al.   Science Advances

Metal–Organic Framework Derived Nanozymes in Biomedicine

(2020) Dongdong Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enzymatically Formed Peptide Assemblies Sequestrate Proteins and Relocate Inhibitors to Selectively Kill Cancer Cells

(2020) Hongjian He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorination Chemistry Enhances NIR‐II Fluorescence of Polymer Dots for Quantitative Brain Tumor Imaging

(2020) Ye Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lysosome-targeting chimaeras for degradation of extracellular proteins

(2020) Steven M. Banik et al.   NATURE

Manumycin polyketides act as molecular glues between UBR7 and P53

(2020) Yosuke Isobe et al.   Nature Chemical Biology

Prospecting for molecular glues

(2020) Willem den Besten et al.   Nature Chemical Biology

Rational discovery of molecular glue degraders via scalable chemical profiling

(2020) Cristina Mayor-Ruiz et al.   Nature Chemical Biology

AIEgen-coupled upconversion nanoparticles eradicate solid tumors through dual-mode ROS activation

(2020) Duo Mao et al.   Science Advances

Boosting O 2 •− Photogeneration via Promoting Intersystem‐Crossing and Electron‐Donating Efficiency of Aza‐BODIPY‐Based Nanoplatforms for Hypoxic‐Tumor Photodynamic Therapy

(2020) Dapeng Chen et al.   Small Methods

A DNA nanodevice-based vaccine for cancer immunotherapy

(2020) Shaoli Liu et al.   NATURE MATERIALS

Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health

(2020) Chelsea N. Fries et al.   Nature Nanotechnology

Endoplasmic reticulum targeted AIE bioprobe as a highly efficient inducer of immunogenic cell death

(2020) Jun Li et al.   Science China-Chemistry

Directly observing intracellular nanoparticle formation with nanocomputed tomography

(2020) Miaomiao Zhang et al.   Science Advances

Methods with Nanoarchitectonics for Small Molecules and Nanostructures to Regulate Living Cells

(2020) Jingwen Song et al.   Small Methods

Targeting immunogenic cell death in cancer

(2020) Asma Ahmed et al.   Molecular Oncology

Size-transformable antigen-presenting cell–mimicking nanovesicles potentiate effective cancer immunotherapy

(2020) Weijing Yang et al.   Science Advances

Supramolecular Nanofibers with Superior Bioactivity to Insulin-Like Growth Factor-I

(2019) Yuna Shang et al.   NANO LETTERS

BODIPY-Based Donor/Donor-Acceptor System: Towards Highly Efficient Long Wavelength-Excitable Near-IR Polymer Dots with Narrow and Strong Absorption Features

(2019) Lei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

(2019) Fangyuan Zhou et al.   ADVANCED MATERIALS

Molecular Glue that Spatiotemporally Turns on Protein–Protein Interactions

(2019) Rina Mogaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intercellular Instructed-Assembly Mimics Protein Dynamics To Induce Cell Spheroids

(2019) Huaimin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

(2019) Filipe Martins et al.   Nature Reviews Clinical Oncology

In Situ Manipulation of Dendritic Cells by an Autophagy-Regulative Nanoactivator Enables Effective Cancer Immunotherapy

(2019) Yi Wang et al.   ACS Nano

Engineering nanoparticles to locally activate T cells in the tumor microenvironment

(2019) Dangge Wang et al.   Science Immunology

New power of self-assembling carbonic anhydrase inhibitor: Short peptide–constructed nanofibers inspire hypoxic cancer therapy

(2019) Jiayang Li et al.   Science Advances

Massively Evoking Immunogenic Cell Death by Focused Mitochondrial Oxidative Stress using an AIE Luminogen with a Twisted Molecular Structure

(2019) Chao Chen et al.   ADVANCED MATERIALS

A Nanoscale Metal-Organic Framework to Mediate Photodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Enhance Antigen Presentation and Cancer Immunotherapy

(2019) Kaiyuan Ni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Situ Self-Assembled Nanofibers Precisely Target Cancer-Associated Fibroblasts for Improved Tumor Imaging

(2019) Xiao-Xiao Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular glue concept solidifies

(2019) Kheewoong Baek et al.   Nature Chemical Biology

Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

(2018) Xiaopin Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Supramolecular Polymer-Based Nanomedicine: High Therapeutic Performance and Negligible Long-Term Immunotoxicity

(2018) Guocan Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sequentially Responsive Therapeutic Peptide Assembling Nanoparticles for Dual-Targeted Cancer Immunotherapy

(2018) Keman Cheng et al.   NANO LETTERS

Immunotherapy: Cancer immunotherapy and the value of cure

(2018) Joseph C. Del Paggio   Nature Reviews Clinical Oncology

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

(2018) Chao Wang et al.   Science Translational Medicine

Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery

(2018) Kangquan Shou et al.   Chemical Science

Polymerization-Enhanced Photosensitization

(2018) Wenbo Wu et al.   Chem

Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

(2018) Yu Chao et al.   Nature Biomedical Engineering

Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment

(2018) Bing Feng et al.   ADVANCED MATERIALS

Strategies to Enhance the Photosensitization: Polymerization and D/A Even-Odd Effect

(2018) Shunjie Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis

(2018) Zhengze Yu et al.   Nature Communications

Therapeutic Considerations and Conjugated Polymer-Based Photosensitizers for Photodynamic Therapy

(2017) Zihui Meng et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression

(2017) Jianqin Lu et al.   Nature Communications

In situ activation of platelets with checkpoint inhibitors for post-surgical cancer immunotherapy

(2017) Chao Wang et al.   Nature Biomedical Engineering

Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody

(2016) Chao Wang et al.   ADVANCED MATERIALS

Cell Environment-Differentiated Self-Assembly of Nanofibers

(2016) Zhen Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PD-1–PD-L1 immune-checkpoint blockade in B-cell lymphomas

(2016) Aaron Goodman et al.   Nature Reviews Clinical Oncology

Tetraphenylethene-based highly emissive metallacage as a component of theranostic supramolecular nanoparticles

(2016) Guocan Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

(2016) Chunbai He et al.   Nature Communications

Blocking of the PD-1/PD-L1 Interaction by aD-Peptide Antagonist for Cancer Immunotherapy

(2015) Hao-Nan Chang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aggregation-Induced Emission: Together We Shine, United We Soar!

(2015) Ju Mei et al.   CHEMICAL REVIEWS

Fine-Tuning of Crystal Packing and Charge Transport Properties of BDOPV Derivatives through Fluorine Substitution

(2015) Jin-Hu Dou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlling Cancer Cell Fate Using Localized Biocatalytic Self-Assembly of an Aromatic Carbohydrate Amphiphile

(2015) Ricardo A. Pires et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

(2015) N. A. Rizvi et al.   SCIENCE

“Conformation Locked” Strong Electron-Deficient Poly(p-Phenylene Vinylene) Derivatives for Ambient-Stable n-Type Field-Effect Transistors: Synthesis, Properties, and Effects of Fluorine Substitution Position

(2014) Ting Lei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging enzyme-triggered self-assembly of small molecules inside live cells

(2012) Yuan Gao et al.   Nature Communications

Organic fluorine compounds: a great opportunity for enhanced materials properties

(2011) Ricarda Berger et al.   CHEMICAL SOCIETY REVIEWS

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Immunogenic death of colon cancer cells treated with oxaliplatin

(2009) A Tesniere et al.   ONCOGENE