Enzymatically Formed Peptide Assemblies Sequestrate Proteins and Relocate Inhibitors to Selectively Kill Cancer Cells

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Dynamic Detection of Active Enzyme Instructed Supramolecular Assemblies In Situ via Super-Resolution Microscopy

(2020) Qingxin Yao et al.   ACS Nano

Multispecific drugs herald a new era of biopharmaceutical innovation

(2020) Raymond J. Deshaies   NATURE

Instructed Assembly as Context-Dependent Signaling for the Death and Morphogenesis of Cells

(2019) Huaimin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intercellular Instructed-Assembly Mimics Protein Dynamics To Induce Cell Spheroids

(2019) Huaimin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme-Instructed Peptide Assemblies Selectively Inhibit Bone Tumors

(2019) Zhaoqianqi Feng et al.   Chem

Surface-Assisted Self-Assembly Strategies Leading to Supramolecular Hydrogels

(2018) Cécile Vigier-Carrière et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Active Probes for Imaging Membrane Dynamics of Live Cells with High Spatial and Temporal Resolution over Extended Time Scales and Areas

(2018) Huaimin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization

(2018) Miguel F. Sanmamed et al.   CELL

Instructed Assembly of Peptides for Intracellular Enzyme Sequestration

(2018) Zhaoqianqi Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Altered cancer metabolism in mechanisms of immunotherapy resistance

(2018) Rishab Ramapriyan et al.   PHARMACOLOGY & THERAPEUTICS

The origins and evolution of macropinocytosis

(2018) Jason S. King et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Alkaline Phosphatase-Triggered Simultaneous Hydrogelation and Chemiluminescence

(2017) Zijuan Hai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Redox-Mediated Disassembly to Build Activatable Trimodal Probe for Molecular Imaging of Biothiols

(2016) Mengmeng Zheng et al.   ACS Nano

Regulating the Rate of Molecular Self-Assembly for Targeting Cancer Cells

(2016) Jie Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzyme-Instructed Self-Assembly for Spatiotemporal Profiling of the Activities of Alkaline Phosphatases on Live Cells

(2016) Jie Zhou et al.   Chem

Semiconducting Polymer Nanoparticles with Persistent Near-Infrared Luminescence for In Vivo Optical Imaging

(2015) Mikael Palner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intracellular Self-Assembly of Taxol Nanoparticles for Overcoming Multidrug Resistance

(2015) Yue Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Taurine Boosts Cellular Uptake of Small d-Peptides for Enzyme-Instructed Intracellular Molecular Self-Assembly

(2015) Jie Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer Cell Death Induced by the Intracellular Self-Assembly of an Enzyme-Responsive Supramolecular Gelator

(2015) Akiko Tanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pericellular Hydrogel/Nanonets Inhibit Cancer Cells

(2014) Yi Kuang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selective and programmed cleavage of GPI-anchored proteins from the surface membrane by phospholipase C

(2011) Alexandra Müller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

High stability of self-assembled peptide nanowires against thermal, chemical, and proteolytic attacks

(2009) Jungki Ryu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Discovery and Validation of a Series of Aryl Sulfonamides as Selective Inhibitors of Tissue-Nonspecific Alkaline Phosphatase (TNAP)

(2009) Russell Dahl et al.   JOURNAL OF MEDICINAL CHEMISTRY

Endosomal Leakage and Nuclear Translocation of Multiwalled Carbon Nanotubes: Developing a Model for Cell Uptake

(2009) Qingxin Mu et al.   NANO LETTERS