Biomimetic Nanoplatform Loading Type I Aggregation-Induced Emission Photosensitizer and Glutamine Blockade to Regulate Nutrient Partitioning for Enhancing Antitumor Immunotherapy

The cancer metabolic reprogramming and immune response

(2021) Longzheng Xia et al.   Molecular Cancer

Dose‐Dependent Carbon‐Dot‐Induced ROS Promote Uveal Melanoma Cell Tumorigenicity via Activation of mTOR Signaling and Glutamine Metabolism

(2021) Yi Ding et al.   Advanced Science

A Feasible Strategy of Fabricating Type I Photosensitizer for Photodynamic Therapy in Cancer Cells and Pathogens

(2021) Kongqi Chen et al.   ACS Nano

Cell-programmed nutrient partitioning in the tumour microenvironment

(2021) Bradley I. Reinfeld et al.   NATURE

Top 10 Challenges in Cancer Immunotherapy

(2020) Priti S. Hegde et al.   IMMUNITY

Tumor Microenvironment, Metabolism, and Immunotherapy

(2020) Ralph J. DeBerardinis   NEW ENGLAND JOURNAL OF MEDICINE

Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

(2020) Franziska Püschel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic reprogramming and cancer progression

(2020) Brandon Faubert et al.   SCIENCE

A vaccine-based nanosystem for initiating innate immunity and improving tumor immunotherapy

(2020) Di-Wei Zheng et al.   Nature Communications

Metabolic Modulation of the Tumor Microenvironment Leads to Multiple Checkpoint Inhibition and Immune Cell Infiltration

(2020) David Kolb et al.   ACS Nano

Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells

(2020) Min-Hee Oh et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

(2020) Lorenzo Galluzzi et al.   Nature Reviews Clinical Oncology

AIEgen-coupled upconversion nanoparticles eradicate solid tumors through dual-mode ROS activation

(2020) Duo Mao et al.   Science Advances

Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer

(2020) Xuan Yi et al.   Science Advances

Burst release of encapsulated annexin A5 in tumours boosts cytotoxic T-cell responses by blocking the phagocytosis of apoptotic cells

(2020) Ling Li et al.   Nature Biomedical Engineering

Acceptor Engineering for Optimized ROS Generation Facilitates Reprogramming Macrophages to M1 Phenotype in Photodynamic Immunotherapy

(2020) Guang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Navigating metabolic pathways to enhance antitumour immunity and immunotherapy

(2019) Xiaoyun Li et al.   Nature Reviews Clinical Oncology

Cancer Cell Membrane Camouflaged Nanoparticles to Realize Starvation Therapy Together with Checkpoint Blockades for Enhancing Cancer Therapy

(2019) Wei Xie et al.   ACS Nano

Light‐Triggered In Situ Gelation to Enable Robust Photodynamic‐Immunotherapy by Repeated Stimulations

(2019) Zhouqi Meng et al.   ADVANCED MATERIALS

Acetate Promotes T Cell Effector Function during Glucose Restriction

(2019) Jing Qiu et al.   Cell Reports

Targeting metabolism to regulate immune responses in autoimmunity and cancer

(2019) Chirag H. Patel et al.   NATURE REVIEWS DRUG DISCOVERY

Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators

(2019) João Conniot et al.   Nature Nanotechnology

Engineering patient-specific cancer immunotherapies

(2019) Lindsay Scheetz et al.   Nature Biomedical Engineering

Massively Evoking Immunogenic Cell Death by Focused Mitochondrial Oxidative Stress using an AIE Luminogen with a Twisted Molecular Structure

(2019) Chao Chen et al.   ADVANCED MATERIALS

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

(2019) Robert D. Leone et al.   SCIENCE

Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

(2018) Yu Chao et al.   Nature Biomedical Engineering

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

(2018) Marc O. Johnson et al.   CELL

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma

(2017) Jeffrey Weber et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Cell Membrane-Coated Upconversion Nanoprobes for Highly Specific Tumor Imaging

(2016) Lang Rao et al.   ADVANCED MATERIALS

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Nutrient Competition: A New Axis of Tumor Immunosuppression

(2015) Madhusudhanan Sukumar et al.   CELL

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

(2015) Ping-Chih Ho et al.   CELL

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL