Temporal analysis of blood–brain barrier disruption and cerebrospinal fluid matrix metalloproteinases in rhesus monkeys subjected to transient ischemic stroke

CSF, blood-brain barrier, and brain drug delivery

(2016) William M. Pardridge   Expert Opinion on Drug Delivery

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Blood−brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury

(2015) Roshini Prakash et al.   CURRENT OPINION IN NEUROLOGY

Attenuation of acute stroke injury in rat brain by minocycline promotes blood–brain barrier remodeling and alternative microglia/macrophage activation during recovery

(2015) Yirong Yang et al.   Journal of Neuroinflammation

The role of TIMPs in regulation of extracellular matrix proteolysis

(2015) Valerie Arpino et al.   MATRIX BIOLOGY

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Unbalanced Metalloproteinase-9 and Tissue Inhibitors of Metalloproteinases Ratios Predict Hemorrhagic Transformation of Lesion in Ischemic Stroke Patients Treated with Thrombolysis: Results from the MAGIC Study

(2015) Benedetta Piccardi et al.   Frontiers in Neurology

A more consistent intraluminal rhesus monkey model of ischemic stroke

(2015) Xunming Ji et al.   Neural Regeneration Research

Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2

(2014) Janet M.C. Ngu et al.   CARDIOVASCULAR PATHOLOGY

Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction

(2014) Dong Fan et al.   CARDIOVASCULAR RESEARCH

Early reperfusion injury is associated to MMP2 and IL-1β elevation in cortical neurons of rats subjected to middle cerebral artery occlusion

(2014) D. Amantea et al.   NEUROSCIENCE

Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke

(2014) Sébastien Lenglet et al.   THROMBOSIS AND HAEMOSTASIS

Early Inhibition of MMP Activity in Ischemic Rat Brain Promotes Expression of Tight Junction Proteins and Angiogenesis During Recovery

(2013) Yi Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Utility of CSF in translational neuroscience

(2013) Elizabeth C. M. de Lange   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

The NINDS Stroke Progress Review Group Final Analysis and Recommendations

(2013) M. A. Moskowitz et al.   STROKE

Matrix Metalloproteinases and Blood-Brain Barrier Disruption in Acute Ischemic Stroke

(2013) Shaheen E. Lakhan et al.   Frontiers in Neurology

Overview and introduction: The blood-brain barrier in health and disease

(2012) N. Joan Abbott et al.   EPILEPSIA

Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson’s disease

(2012) Valerio Pisani et al.   Journal of Neuroinflammation

Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood-Brain Barrier Damage in Early Ischemic Stroke Stage

(2012) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Nonhuman Primate Models of Stroke for Translational Neuroprotection Research

(2012) Douglas J. Cook et al.   Neurotherapeutics

Matrix Metalloproteinase-10 Effectively Reduces Infarct Size in Experimental Stroke by Enhancing Fibrinolysis via a Thrombin-Activatable Fibrinolysis Inhibitor–Mediated Mechanism

(2011) J. Orbe et al.   CIRCULATION

Lack of Tissue Inhibitor of Metalloproteinases 2 Leads to Exacerbated Left Ventricular Dysfunction and Adverse Extracellular Matrix Remodeling in Response to Biomechanical Stress

(2011) Vijay Kandalam et al.   CIRCULATION

Reduced TIMP-2 in hypoxia enhances angiogenesis

(2010) Nitza Lahat et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Biochemical Markers for Blood-Brain Barrier Dysfunction in Acute Ischemic Stroke Correlate with Evolution and Outcome

(2010) Raf Brouns et al.   EUROPEAN NEUROLOGY

Valproic Acid Attenuates Blood–Brain Barrier Disruption in a Rat Model of Transient Focal Cerebral Ischemia: The Roles of HDAC and MMP-9 Inhibition

(2010) Zhifei Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Increased Plasma and Tissue MMP Levels are Associated with BCSFB and BBB Disruption Evident on Post-Contrast FLAIR after Experimental Stroke

(2010) Ayush Batra et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Matrix Metalloproteinase-13 is Activated and is found in the Nucleus of Neural Cells after Cerebral Ischemia

(2008) Eloy Cuadrado et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Tissue Inhibitor of Metalloproteinases Protect Blood—Brain Barrier Disruption in Focal Cerebral Ischemia

(2008) Motoaki Fujimoto et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM