Proton myo-inositol cotransporter is a novel γ-secretase associated protein that regulates Aβ production without affecting Notch cleavage

Human brain proteins showing neuron-specific interactions with γ-secretase

(2015) Mitsuhiro Inoue et al.   FEBS Journal

The Role of Phosphoinositides in Synapse Function

(2014) Yoshibumi Ueda   MOLECULAR NEUROBIOLOGY

Visualizing Active Enzyme Complexes Using a Photoreactive Inhibitor for Proximity Ligation – Application on γ-Secretase

(2013) Sophia Schedin-Weiss et al.   PLoS One

Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production

(2012) Yasuhiro Teranishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Novel γ-Secretase-associated Proteins in Detergent-resistant Membranes from Brain

(2012) Ji-Yeun Hur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Second Generation γ-Secretase Modulators Exhibit Different Modulation of Notch β and Aβ Production

(2012) Johanna Wanngren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing

(2012) Susanne Frykman et al.   NEUROCHEMISTRY INTERNATIONAL

Identification of Presenilin 1-Selective γ-Secretase Inhibitors with Reconstituted γ-Secretase Complexes

(2011) Julie Lee et al.   BIOCHEMISTRY

γ-Secretase inhibitors and modulators for Alzheimer’s disease

(2011) Michael S. Wolfe   JOURNAL OF NEUROCHEMISTRY

Potent amyloidogenicity and pathogenicity of Aβ43

(2011) Takashi Saito et al.   NATURE NEUROSCIENCE

Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease

(2010) Gen He et al.   NATURE

Presenilin-dependent regulated intramembrane proteolysis and γ-secretase activity

(2009) J. V. McCarthy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Affinity pulldown of γ-secretase and associated proteins from human and rat brain

(2009) Yasuhiro Teranishi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Aβ43 is more frequent than Aβ40 in amyloid plaque cores from Alzheimer disease brains

(2009) Hedvig Welander et al.   JOURNAL OF NEUROCHEMISTRY

Analysis of the γ-secretase interactome and validation of its association with tetraspanin-enriched microdomains

(2009) Tomoko Wakabayashi et al.   NATURE CELL BIOLOGY

Pen2 and Presenilin-1 Modulate the Dynamic Equilibrium of Presenilin-1 and Presenilin-2 γ-Secretase Complexes

(2008) Lisa Placanica et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Amyloid Precursor Protein Processing by BACE1, the β-Secretase, in Alzheimer Disease Pathophysiology

(2008) Sarah L. Cole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY