Tumour cells are sensitised to ferroptosis via RB1CC1‐mediated transcriptional reprogramming

Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple negative breast cancer cells

(2021) Yahui Ding et al.   Journal of Hematology & Oncology

Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52

(2021) Tao Fu et al.   Science Advances

MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling

(2020) Divya Venkatesh et al.   GENES & DEVELOPMENT

Histone demethylase KDM3B protects against ferroptosis by upregulating SLC7A11

(2020) Yishu Wang et al.   FEBS Open Bio

Lipid peroxidation and ferroptosis: The role of GSH and GPx4

(2020) Fulvio Ursini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Systematic analysis of a mitochondrial disease‐causing ND6 mutation in mitochondrial deficiency

(2020) Deyu Chen et al.   Molecular Genetics & Genomic Medicine

Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation

(2020) Maria Samata et al.   CELL

Paclitaxel induces apoptosis through the TAK1–JNK activation pathway

(2020) Di Yu‐Wei et al.   FEBS Open Bio

Ferroptosis and Cancer: Mitochondria Meet the “Iron Maiden” Cell Death

(2020) Anna Martina Battaglia et al.   Cells

Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy

(2020) Amelia E Ohnstad et al.   EMBO JOURNAL

FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells

(2020) Zeng Ye et al.   Redox Biology

FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates

(2019) Eleonora Turco et al.   MOLECULAR CELL

JNK signaling in cancer cell survival

(2019) Qinghua Wu et al.   MEDICINAL RESEARCH REVIEWS

How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates

(2019) Eleonora Turco et al.   Autophagy

Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53

(2019) Yufei Wang et al.   EMBO REPORTS

AKAP79/150 recruits the transcription factor NFAT to regulate signaling to the nucleus by neuronal L-type Ca2+ channels.

(2019) Jonathan G. Murphy et al.   MOLECULAR BIOLOGY OF THE CELL

Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling

(2019) Jiao Wu et al.   NATURE

Ferroptosis is governed by differential regulation of transcription in liver cancer

(2019) Xiao Zhang et al.   Redox Biology

Endogenous leptin promotes autophagy in EBSS-induced PFCs

(2019) Deling Jiao et al.   Animal Cells and Systems

Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

(2019) Toshitaka Nakamura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Spatiotemporally Tracking the Programmable Mitochondrial Membrane Potential Evolutions by a Robust Molecular Rotor

(2019) Kaiyue Tan et al.   Small

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

(2019) Kirill Bersuker et al.   NATURE

Determinants of enhancer and promoter activities of regulatory elements

(2019) Robin Andersson et al.   NATURE REVIEWS GENETICS

High glucose augments ROS generation regulates mitochondrial dysfunction and apoptosis via stress signalling cascades in keratinocytes

(2019) Huma Rizwan et al.   LIFE SCIENCES

CCPG1 is a noncanonical autophagy cargo receptor essential for reticulophagy and pancreatic ER proteostasis

(2018) Vikramjit Lahiri et al.   Autophagy

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy

(2018) J.G.C. Peeters et al.   Autophagy

BAP1 links metabolic regulation of ferroptosis to tumour suppression

(2018) Yilei Zhang et al.   NATURE CELL BIOLOGY

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

(2017) Matthew J. Hangauer et al.   NATURE

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC

(2016) Bruce Do Van et al.   NEUROBIOLOGY OF DISEASE

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Inhibitor of Nicotinamide Phosphoribosyltransferase Sensitizes Glioblastoma Cells to Temozolomide via Activating ROS/JNK Signaling Pathway

(2016) Jun Feng et al.   Biomed Research International

Redox Homeostasis and Mitochondrial Dynamics

(2015) Peter H.G.M. Willems et al.   Cell Metabolism

Fluoride induces oxidative damage and SIRT1/autophagy through ROS-mediated JNK signaling

(2015) Maiko Suzuki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

(2015) Xiaofang Sun et al.   HEPATOLOGY

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

HSPB1 as a novel regulator of ferroptotic cancer cell death

(2015) X Sun et al.   ONCOGENE

A Code for RanGDP Binding in Ankyrin Repeats Defines a Nuclear Import Pathway

(2014) Min Lu et al.   CELL

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Synergistic cytotoxicity of gemcitabine, clofarabine and edelfosine in lymphoma cell lines

(2014) B C Valdez et al.   Blood Cancer Journal

Atg9 Interacts with dTRAF2/TRAF6 to Regulate Oxidative Stress-Induced JNK Activation and Autophagy Induction

(2013) Hong-Wen Tang et al.   DEVELOPMENTAL CELL

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200

(2011) Eugenia Morselli et al.   CELL CYCLE

Rac1 Takes Center Stage in Pancreatic Cancer and Ulcerative Colitis: Quantity Matters

(2011) Eva Wertheimer et al.   GASTROENTEROLOGY

hElp3 Directly Modulates the Expression of HSP70 Gene in HeLa Cells via HAT Activity

(2011) Fen Li et al.   PLoS One

ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function

(2010) Manjula Darshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

RB1CC1 Activates RB1 Pathway and Inhibits Proliferation and Cologenic Survival in Human Cancer

(2010) Tokuhiro Chano et al.   PLoS One

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Separation and detection of large phosphoproteins using Phos-tag SDS-PAGE

(2009) Eiji Kinoshita et al.   Nature Protocols

Spatial Interplay between PIASy and FIP200 in the Regulation of Signal Transduction and Transcriptional Activity

(2008) N. Martin et al.   MOLECULAR AND CELLULAR BIOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY