Paclitaxel induces apoptosis through the TAK1–JNK activation pathway

Zinc promotes prostate cancer cell chemosensitivity to paclitaxel by inhibiting epithelial‐mesenchymal transition and inducing apoptosis

(2019) Ya‐Nan Xue et al.   PROSTATE

Plumbagin Increases Paclitaxel-Induced Cell Death and Overcomes Paclitaxel Resistance in Breast Cancer Cells through ERK-Mediated Apoptosis Induction

(2019) Anna Kawiak et al.   JOURNAL OF NATURAL PRODUCTS

Diosmetin induces apoptosis and enhances the chemotherapeutic efficacy of paclitaxel in non‐small cell lung cancer cells via Nrf2 inhibition

(2019) Xiangcui Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Combined bazedoxifene and paclitaxel treatments inhibit cell viability, cell migration, colony formation, and tumor growth and induce apoptosis in breast cancer

(2019) Shengling Fu et al.   CANCER LETTERS

Tooniliatone A sensitizes multidrug resistant cancer cells by decreasing Bcl-xL via activation of JNK MAPK signaling

(2019) Yun Li et al.   PHYTOMEDICINE

TAK1 mediates apoptosis via p38 involve in ischemia-induced renal fibrosis

(2018) Jun Zhou et al.   Artificial Cells Nanomedicine and Biotechnology

Disruption of protein neddylation with MLN4924 attenuates paclitaxel-induced apoptosis and microtubule polymerization in ovarian cancer cells

(2018) Xiaoling Hong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enhancement of hyperthermia-induced apoptosis by 5Z-7-oxozeaenol, a TAK1 inhibitor, in Molt-4 cells

(2017) Peng Li et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

POPX2 phosphatase regulates apoptosis through the TAK1-IKK-NF-κB pathway

(2017) Ting Weng et al.   Cell Death & Disease

TAK1 inhibitor 5Z-7-oxozeaenol sensitizes cervical cancer to doxorubicin-induced apoptosis

(2017) Shan Guan et al.   Oncotarget

An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells

(2017) Yifang Xie et al.   Scientific Reports

Enhancement of hyperthermia-induced apoptosis by 5Z-7-oxozeaenol, a TAK1 inhibitor, in A549 cells

(2016) Peng Li et al.   CELL STRESS & CHAPERONES

Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway

(2016) Z.G. Peng et al.   GENETICS AND MOLECULAR RESEARCH

Rb-mediated apoptosis or proliferation: It's up to JNK

(2015) Bertrand Mollereau et al.   CELL CYCLE

Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling

(2014) Zhilin Qi et al.   CELLULAR SIGNALLING

Synergistic Effect of COX-2 Inhibitor on Paclitaxel-Induced Apoptosis in the Human Ovarian Cancer Cell Line OVCAR-3

(2014) Hee Jung Kim et al.   Cancer Research and Treatment

p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

(2013) Xinbing Sui et al.   CANCER LETTERS

Activation of TAK1 by Sef-S induces apoptosis in 293T cells

(2013) Xiaojun Sun et al.   CELLULAR SIGNALLING

Chemical biology suggests a role for calcium signaling in mediating sustained JNK activation during apoptosis

(2010) Slavica Brnjic et al.   Molecular BioSystems

Potentiation of paclitaxel-induced apoptosis by galectin-13 overexpression via activation of Ask-1-p38-MAP kinase and JNK/SAPK pathways and suppression of Akt and ERK1/2 activation in U-937 human macrophage cells

(2009) Arpad Boronkai et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Ran suppresses paclitaxel-induced apoptosis in human glioblastoma cells

(2008) Im Sun Woo et al.   APOPTOSIS

Melittin, a Major Component of Bee Venom, Sensitizes Human Hepatocellular Carcinoma Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis by Activating CaMKII-TAK1-JNK/p38 and Inhibiting IκBα Kinase-NFκB

(2008) Chen Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE

Homeostatic interactions between MEKK3 and TAK1 involved in NF-κB signaling

(2007) Yuwei Di et al.   CELLULAR SIGNALLING