Synergistic cytotoxicity of gemcitabine, clofarabine and edelfosine in lymphoma cell lines

Mechanistic studies on the synergistic cytotoxicity of the nucleoside analogs gemcitabine and clofarabine in multiple myeloma: Relevance of p53 and its clinical implications

(2013) Benigno C. Valdez et al.   EXPERIMENTAL HEMATOLOGY

Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

(2013) M Reis-Sobreiro et al.   Blood Cancer Journal

Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines

(2012) Benigno C. Valdez et al.   EXPERIMENTAL HEMATOLOGY

ATF2 – at the crossroad of nuclear and cytosolic functions

(2012) Eric Lau et al.   JOURNAL OF CELL SCIENCE

Edelfosine and perifosine disrupt hepatic mitochondrial oxidative phosphorylation and induce the permeability transition

(2012) Ana Burgeiro et al.   MITOCHONDRION

Exogenous Ether Lipids Predominantly Target Mitochondria

(2012) Lars Kuerschner et al.   PLoS One

Caspase-3 is a target gene of c-Jun:ATF2 heterodimers during apoptosis induced by activity deprivation in cerebellar granule neurons

(2011) Bin Song et al.   NEUROSCIENCE LETTERS

Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum

(2011) C Gajate et al.   ONCOGENE

Lipid Rafts and Fas/CD95 Signaling in Cancer Chemotherapy

(2011) Consuelo Gajate et al.   Recent Patents on Anti-Cancer Drug Discovery

The synergistic cytotoxicity of clofarabine, fludarabine and busulfan in AML cells involves ATM pathway activation and chromatin remodeling

(2010) Benigno C. Valdez et al.   BIOCHEMICAL PHARMACOLOGY

In vitro and In vivo Selective Antitumor Activity of Edelfosine against Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Involving Lipid Rafts

(2010) F. Mollinedo et al.   CLINICAL CANCER RESEARCH

Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells

(2009) S.-M. Shen et al.   CARCINOGENESIS

The proapoptotic dp5 gene is a direct target of the MLK-JNK-c-Jun pathway in sympathetic neurons

(2009) E. Towers et al.   NUCLEIC ACIDS RESEARCH

Involvement of Raft Aggregates Enriched in Fas/CD95 Death-Inducing Signaling Complex in the Antileukemic Action of Edelfosine in Jurkat Cells

(2009) Consuelo Gajate et al.   PLoS One

Anticancer Alkylphospholipids: Mechanisms of Action, Cellular Sensitivity and Resistance, and Clinical Prospects

(2008) Wim van Blitterswijk et al.   CURRENT PHARMACEUTICAL DESIGN

Nucleoside analogs: molecular mechanisms signaling cell death

(2008) B Ewald et al.   ONCOGENE