Vitamin C Attenuates Oxidative Stress, Inflammation, and Apoptosis Induced by Acute Hypoxia through the Nrf2/Keap1 Signaling Pathway in Gibel Carp (Carassius gibelio)

Are antioxidant enzymes essential markers in the diagnosis and monitoring of cancer patients – A review

(2021) Elżbieta Cecerska-Heryć et al.   CLINICAL BIOCHEMISTRY

Resveratrol ameliorates thoracic blast exposure-induced inflammation, endoplasmic reticulum stress and apoptosis in the brain through the Nrf2/Keap1 and NF-κB signaling pathway

(2021) Peifang Cong et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Ascorbic Acid Regulates the Immunity, Anti-Oxidation and Apoptosis in Abalone Haliotis discus hannai Ino

(2021) Kai Luo et al.   Antioxidants

Nephroprotective Role of Chrysophanol in Hypoxia/Reoxygenation-Induced Renal Cell Damage via Apoptosis, ER Stress, and Ferroptosis

(2021) Chih-Hung Lin et al.   Biomedicines

Emodin alleviates acute hypoxia-induced apoptosis in gibel carp (Carassius gibelio) by upregulating autophagy through modulation of the AMPK/mTOR pathway

(2021) Liyun Wu et al.   AQUACULTURE

Crosstalk Between Hypoxia and ER Stress Response: A Key Regulator of Macrophage Polarization

(2020) Paula Díaz-Bulnes et al.   Frontiers in Immunology

Combined exposure to hypoxia and ammonia aggravated biological effects on glucose metabolism, oxidative stress, inflammation and apoptosis in largemouth bass (Micropterus salmoides)

(2020) Liulan Zhao et al.   AQUATIC TOXICOLOGY

TRIM16 protects from OGD/R-induced oxidative stress in cultured hippocampal neurons by enhancing Nrf2/ARE antioxidant signaling via downregulation of Keap1

(2020) Xiaoyan Ren et al.   EXPERIMENTAL CELL RESEARCH

Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy

(2020) Ching-Ying Huang et al.   Nutrients

Unfolded protein response in cardiovascular disease

(2020) Khadeja-Tul Kubra et al.   CELLULAR SIGNALLING

Response of AMP-activated protein kinase and lactate metabolism of largemouth bass (Micropterus salmoides) under acute hypoxic stress

(2019) S. Yang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effects of Dietary Carbohydrate and Lipid Concentrations on Growth Performance, Feed Utilization, Glucose, and Lipid Metabolism in Two Strains of Gibel Carp

(2019) Hongyan Li et al.   Frontiers in Veterinary Science

Endoplasmic reticulum stress and autophagy contribute to cadmium-induced cytotoxicity in retinal pigment epithelial cells

(2019) Lingmin Zhang et al.   TOXICOLOGY LETTERS

Endoplasmic Reticulum Stress Activates Unfolded Protein Response Signaling and Mediates Inflammation, Obesity, and Cardiac Dysfunction: Therapeutic and Molecular Approach

(2019) Omar Mohammed Amen et al.   Frontiers in Pharmacology

Emodin ameliorates metabolic and antioxidant capacity inhibited by dietary oxidized fish oil through PPARs and Nrf2-Keap1 signaling in Wuchang bream (Megalobrama amblycephala)

(2019) Changyou Song et al.   FISH & SHELLFISH IMMUNOLOGY

Understanding the Role of the Unfolded Protein Response Sensor IRE1 in the Biology of Antigen Presenting Cells

(2019) Felipe Flores-Santibáñez et al.   Cells

Oxidative Stress and Cancer: The Role of Nrf2

(2018) Soraya Sajadimajd et al.   CURRENT CANCER DRUG TARGETS

Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways

(2018) Faisal Imam et al.   Pharmacological Reports

Nrf2-p62 autophagy pathway and its response to oxidative stress in hepatocellular carcinoma

(2018) Desirée Bartolini et al.   Translational Research

Hepatoprotective benefits of vitamin C against perfluorooctane sulfonate-induced liver damage in mice through suppressing inflammatory reaction and ER stress

(2018) Min Su et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Overexpression of HIF-1a could partially protect K562 cells from 1,4-benzoquinone induced toxicity by inhibiting ROS, apoptosis and enhancing glycolysis

(2018) Rongli Sun et al.   TOXICOLOGY IN VITRO

Withaferin A induced impaired autophagy and unfolded protein response in human breast cancer cell-lines MCF-7 and MDA-MB-231

(2017) Kamalini Ghosh et al.   TOXICOLOGY IN VITRO

Vitamin C Status and Cognitive Function: A Systematic Review

(2017) Nikolaj Travica et al.   Nutrients

Antioxidant Therapeutic Strategies for Cardiovascular Conditions Associated with Oxidative Stress

(2017) Jorge Farías et al.   Nutrients

Oxidative stress and apoptosis after acute respiratory hypoxia and reoxygenation in rat brain

(2017) Debora Coimbra-Costa et al.   Redox Biology

Activation of apoptosis signalling pathways by reactive oxygen species

(2016) Maureen Redza-Dutordoir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neferine prevents autophagy induced by hypoxia through activation of Akt/mTOR pathway and Nrf2 in muscle cells

(2016) Rathinasamy Baskaran et al.   BIOMEDICINE & PHARMACOTHERAPY

Nrf2 protects mitochondrial decay by oxidative stress

(2016) Joshua Strom et al.   FASEB JOURNAL

Dietary vitamin C deficiency depresses the growth, head kidney and spleen immunity and structural integrity by regulating NF-κB, TOR, Nrf2, apoptosis and MLCK signaling in young grass carp (Ctenopharyngodon idella)

(2016) Hui-Jun Xu et al.   FISH & SHELLFISH IMMUNOLOGY

Methyl syringate, a TRPA1 agonist represses hypoxia-induced cyclooxygenase-2 in lung cancer cells

(2016) Joonwoo Park et al.   PHYTOMEDICINE

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

(2016) Eri H. Kobayashi et al.   Nature Communications

Effect of dietary vitamin C on the growth performance, antioxidant ability and innate immunity of juvenile yellow catfish (Pelteobagrus fulvidracoRichardson)

(2015) Xiong-Pei Liang et al.   AQUACULTURE RESEARCH

A Lactate-Induced Response to Hypoxia

(2015) Dong Chul Lee et al.   CELL

Hypoxia-Inducible Factor-2  Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury

(2015) J. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia

(2015) Han Seok Koh et al.   Nature Communications

Vitamin C Mitigates Oxidative Stress and Tumor Necrosis Factor-Alpha in Severe Community-Acquired Pneumonia and LPS-Induced Macrophages

(2014) Yuanyuan Chen et al.   MEDIATORS OF INFLAMMATION

The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia

(2013) Marco B.E. Schaaf et al.   RADIOTHERAPY AND ONCOLOGY

The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity

(2012) Norma Masson et al.   EMBO REPORTS

Effects of emodin and vitamin C on growth performance, biochemical parameters and two HSP70s mRNA expression of Wuchang bream (Megalobrama amblycephala Yih) under high temperature stress

(2012) Jianhua Ming et al.   FISH & SHELLFISH IMMUNOLOGY

Dynamics of Nrf2 and Keap1 in ARE-MediatedNQO1Expression by Wasabi 6-(Methylsulfinyl)hexyl Isothiocyanate

(2011) De-Xing Hou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Regulation of autophagy by ATF4 in response to severe hypoxia

(2010) T Rzymski et al.   ONCOGENE

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

(2009) Kasper M.A. Rouschop et al.   JOURNAL OF CLINICAL INVESTIGATION