Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 9, Issue 6, Pages 1864-1870Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0ob00847h
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Funding
- Ramsay Memorial Trust
- One North East and HEFCE for a Durham Bridging Fellowship
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Herein, we report the synthesis of novel phenylalanine and tyrosine derivatives containing a N-methyliminodiacetic acid boronate group. These compounds can be prepared enantiomerically pure, they are stable to column chromatography and they can be stored in air for two months without degradation occurring. This new class of boronate containing aromatic amino acids has potential applications in both peptide chemistry and natural product synthesis.
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