A Novel Domain-Specific Mutation in a Sclerosteosis Patient Suggests a Role of LRP4 as an Anchor for Sclerostin in Human Bone
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Title
A Novel Domain-Specific Mutation in a Sclerosteosis Patient Suggests a Role of LRP4 as an Anchor for Sclerostin in Human Bone
Authors
Keywords
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Journal
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 31, Issue 4, Pages 874-881
Publisher
Wiley
Online
2016-01-12
DOI
10.1002/jbmr.2782
References
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- Bone Overgrowth-associated Mutations in theLRP4Gene Impair Sclerostin Facilitator Function
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- Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis
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- LRP4 Mutations Alter Wnt/β-Catenin Signaling and Cause Limb and Kidney Malformations in Cenani-Lenz Syndrome
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- Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis
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- Sclerosteosis - An autosomal recessive disorder
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- First missense mutation in the SOST gene causing sclerosteosis by loss of sclerostin function
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- Lrp4, a Novel Receptor for Dickkopf 1 and Sclerostin, Is Expressed by Osteoblasts and Regulates Bone Growth and Turnover In Vivo
- (2009) Hong Y. Choi et al. PLoS One
- The Binding Between Sclerostin and LRP5 is Altered by DKK1 and by High-Bone Mass LRP5 Mutations
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