Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer

Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells

(2021) Alejandro Morales et al.   LABORATORY INVESTIGATION

Diverse molecular mechanisms contribute to differential expression of human duplicated genes

(2021) Colin J Shew et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Value of EphB2 Receptor and Cognate Ephrin Ligands in Prognostic and Predictive Assessments of Human Breast Cancer

(2021) Abdul Shukkur Ebrahim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Race as a Contributor to Stromal Modulation of Tumor Progression

(2021) Mamatha Kakarla et al.   Cancers

Expression Patterns of Microenvironmental Factors and Tenascin-C at the Invasive Front of Stage II and III Colorectal Cancer: Novel Tumor Prognostic Markers

(2021) Mai Hashimoto et al.   Frontiers in Oncology

Neoadjuvant therapy alters the collagen architecture of pancreatic cancer tissue via Ephrin-A5

(2021) Kosei Nakajima et al.   BRITISH JOURNAL OF CANCER

Fibroblast heterogeneity in prostate carcinogenesis

(2021) Sathyavathi ChallaSivaKanaka et al.   CANCER LETTERS

EFNB1 Acts as a Novel Prognosis Marker in Glioblastoma through Bioinformatics Methods and Experimental Validation

(2021) Yaohong Shi et al.   Journal of Oncology

Targeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo

(2020) Guifang Du et al.   Cell Death & Disease

Regulation of Src Family Kinases during Colorectal Cancer Development and Its Clinical Implications

(2020) Wook Jin   Cancers

The differential expression patterns of paralogs in response to stresses indicate expression and sequence divergences

(2020) Shuaibin Lian et al.   BMC PLANT BIOLOGY

Heterogeneity of cancer‐associated fibroblasts: Opportunities for precision medicine

(2020) Ryu Kanzaki et al.   CANCER SCIENCE

The Role of Cancer-Associated Fibroblasts in Prostate Cancer Tumorigenesis

(2020) Francesco Bonollo et al.   Cancers

Roles of EphA1/A2 and ephrin-A1 in cancer

(2019) Katsuaki Ieguchi et al.   CANCER SCIENCE

Impact of Epithelial–Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ

(2019) Carina Strell et al.   JNCI-Journal of the National Cancer Institute

In search of definitions: Cancer-associated fibroblasts and their markers

(2019) Martin Nurmik et al.   INTERNATIONAL JOURNAL OF CANCER

Inflammation and Cancer: Triggers, Mechanisms, and Consequences

(2019) Florian R. Greten et al.   IMMUNITY

Heterogeneity of human prostate carcinoma‐associated fibroblasts implicates a role for subpopulations in myeloid cell recruitment

(2019) Renee E. Vickman et al.   PROSTATE

Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer

(2019) Yen-Liang Liu et al.   Cancers

Targeting the tumour stroma to improve cancer therapy

(2018) Kenneth C. Valkenburg et al.   Nature Reviews Clinical Oncology

Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export

(2018) Nil Ege et al.   Cell Systems

Elevated Stromal Inflammatory Mediators Promote Prostate Cancer Progression in African American Men

(2018) Marc Gillard et al.   CANCER RESEARCH

Chronic hypoxia-induced slug promotes invasive behavior of prostate cancer cells by activating expression of ephrin-B1

(2018) Kazunori Iwasaki et al.   CANCER SCIENCE

Mutual dependence of the MRTF–SRF and YAP–TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics

(2017) Charles T. Foster et al.   GENES & DEVELOPMENT

EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1

(2017) H J Cho et al.   ONCOGENE

Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis

(2016) Yanli Yan et al.   KIDNEY INTERNATIONAL

Suppression of SRC Signaling Is Effective in Reducing Synergy between Glioblastoma and Stromal Cells

(2016) Alessia Calgani et al.   MOLECULAR CANCER THERAPEUTICS

Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer

(2016) Ghazal Efazat et al.   Oncotarget

The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of Integrin-β8 in prostate cancer cells

(2015) Inga Mertens-Walker et al.   BMC CANCER

Overexpression of Ephrin A2 receptors in cancer stromal cells is a prognostic factor for the relapse of gastric cancer

(2014) Shojiro Kikuchi et al.   Gastric Cancer

Tumor Microenvironment and Metabolism in Prostate Cancer

(2014) Paola Chiarugi et al.   SEMINARS IN ONCOLOGY

Eph receptors and their ligands: Promising molecular biomarkers and therapeutic targets in prostate cancer

(2013) Jessica E. Lisle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Extracellular matrix signaling in morphogenesis and repair

(2013) Kelly C Clause et al.   CURRENT OPINION IN BIOTECHNOLOGY

Association between baseline VEGF/sVEGFR-2 and VEGF/TSP-1 ratios and response to metronomic chemotherapy using cyclophosphamide and celecoxib in patients with advanced breast cancer

(2013) OG Scharovsky et al.   INDIAN JOURNAL OF CANCER

DNASU plasmid and PSI:Biology-Materials repositories: resources to accelerate biological research

(2013) Catherine Y. Seiler et al.   NUCLEIC ACIDS RESEARCH

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Altered TGF-β Signaling in a Subpopulation of Human Stromal Cells Promotes Prostatic Carcinogenesis

(2011) Omar E. Franco et al.   CANCER RESEARCH

Evidence for a dual function of EphB4 as tumor promoter and suppressor regulated by the absence or presence of the ephrin-B2 ligand

(2011) Raphael Rutkowski et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor microenvironment and progression

(2011) Harold F. Dvorak et al.   JOURNAL OF SURGICAL ONCOLOGY

Non-SH2/PDZ reverse signaling by ephrins

(2011) Ira O. Daar   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Clinical relevance of Ephs and ephrins in cancer: Lessons from breast, colorectal, and lung cancer profiling

(2011) Dana M. Brantley-Sieders   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding

(2010) M. L. Bochenek et al.   JOURNAL OF CELL SCIENCE

Cancer associated fibroblasts (CAFs) in tumor microenvironment

(2009) Fei Xing   Frontiers in Bioscience-Landmark

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Cancer associated fibroblasts in cancer pathogenesis

(2009) Omar E. Franco et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cancer and the tumor microenvironment: a review of an essential relationship

(2008) Flaubert Mbeunkui et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Eph-Ephrin Bidirectional Signaling in Physiology and Disease

(2008) Elena B. Pasquale   CELL

Bidirectional modulation of synaptic functions by Eph/ephrin signaling

(2008) Rüdiger Klein   NATURE NEUROSCIENCE

Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530

(2008) Y-M Chang et al.   ONCOGENE