Decreased Serum Levels of SIRT1 and SIRT3 Correlate with Severity of Skin and Lung Fibrosis and Peripheral Microvasculopathy in Systemic Sclerosis

The Treatment of Lung Involvement in Systemic Sclerosis

(2021) Barbara Ruaro et al.   Pharmaceuticals

The Role of Pro-fibrotic Myofibroblasts in Systemic Sclerosis: from Origin to Therapeutic Targeting

(2021) Eloisa Romano et al.   CURRENT MOLECULAR MEDICINE

New promising drugs for the treatment of systemic sclerosis: pathogenic considerations, enhanced classifications, and personalized medicine

(2021) Alain Lescoat et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Serum sirtuin 1 is independently associated with intact PTH among patients with chronic kidney disease

(2021) Angelika Bielach-Bazyluk et al.   Clinical Interventions in Aging

SIRT1 attenuates renal fibrosis by repressing HIF-2α

(2021) Peipei Li et al.   Cell Death Discovery

Idiopathic pulmonary fibrosis and systemic sclerosis: pathogenic mechanisms and therapeutic interventions

(2021) Hamid Mattoo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Current Concepts on the Pathogenesis of Systemic Sclerosis

(2021) Marie Elise Truchetet et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

SIRT3 Overexpression Ameliorates Asbestos-Induced Pulmonary Fibrosis, mt-DNA Damage, and Lung Fibrogenic Monocyte Recruitment

(2021) Paul Cheresh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Serum levels of SIRT3 and other inflammatory factors are associated with clinical outcomes and prognosis in severe community-acquired pneumonia in adults

(2021) Wei Zhu et al.   MEDICINE

Similarities between COVID-19 and systemic sclerosis early vasculopathy: A “viral” challenge for future research in scleroderma

(2021) Marco Matucci-Cerinic et al.   AUTOIMMUNITY REVIEWS

A comprehensive review of Sirtuins: With a major focus on redox homeostasis and metabolism

(2021) Shahab Shahgaldi et al.   LIFE SCIENCES

High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients

(2021) Barbara Ruaro et al.   Diagnostics

Predictors of progression in systemic sclerosis patients with interstitial lung disease

(2020) Oliver Distler et al.   EUROPEAN RESPIRATORY JOURNAL

Role of Sirtuins in Tumor Angiogenesis

(2020) Lincy Edatt et al.   Frontiers in Oncology

Sirtuins family as a target in endothelial cell dysfunction: implications for vascular ageing

(2020) Hai-na Zhang et al.   BIOGERONTOLOGY

The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis

(2020) Edyta Zbroch et al.   Clinical Interventions in Aging

Sirtuins as endogenous regulators of lung fibrosis: A current perspective

(2020) Somnath Mazumder et al.   LIFE SCIENCES

SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition

(2019) Zhen-Hua Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Sirtuin1 Protects against Systemic Sclerosis–related Pulmonary Fibrosis by Decreasing Proinflammatory and Profibrotic Processes

(2018) Haiyan Chu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sirtuins in Renal Health and Disease

(2018) Marina Morigi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sirtuins and Accelerated Aging in Scleroderma

(2018) Anne E. Wyman et al.   Current Rheumatology Reports

Emerging role of SIRT3 in endothelial metabolism, angiogenesis, and cardiovascular disease

(2018) Xiaochen He et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Prognostic value of Sirtuin1 in acute ischemic stroke and its correlation with functional outcomes

(2018) Yang Liu et al.   MEDICINE

SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis

(2017) Renea P. Jablonski et al.   FASEB JOURNAL

Sirt1 ameliorates systemic sclerosis by targeting the mTOR pathway

(2017) Xiaoxia Zhu et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction

(2017) Xiaochen He et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Systemic sclerosis

(2017) Christopher P Denton et al.   LANCET

Ablation of SIRT3 causes coronary microvascular dysfunction and impairs cardiac recovery post myocardial ischemia

(2016) Xiaochen He et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis

(2016) Meredith L. Sosulski et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis

(2016) Kaname Akamata et al.   Oncotarget

Letter to the editor: Decreased SIRT3 expression is a good potential biomarker associated with diseases

(2015) Wei-Li Yu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vascular biomarkers and correlation with peripheral vasculopathy in systemic sclerosis

(2015) Inês Chora et al.   AUTOIMMUNITY REVIEWS

The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling

(2015) Jun Wei et al.   Arthritis & Rheumatology

Identification of serum sirtuins as novel noninvasive protein markers for frailty

(2014) Rahul Kumar et al.   AGING CELL

Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis

(2014) Pawel Zerr et al.   ANNALS OF THE RHEUMATIC DISEASES

Apelin gene therapy increases myocardial vascular density and ameliorates diabetic cardiomyopathy via upregulation of sirtuin 3

(2013) Heng Zeng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative

(2013) Frank van den Hoogen et al.   ANNALS OF THE RHEUMATIC DISEASES

Mechanisms in the loss of capillaries in systemic sclerosis: angiogenesis versus vasculogenesis

(2010) Mirko Manetti et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Scoring the nailfold microvascular changes during the capillaroscopic analysis in systemic sclerosis patients

(2007) A Sulli et al.   ANNALS OF THE RHEUMATIC DISEASES