The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate against Shigella
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Title
The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate against Shigella
Authors
Keywords
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Journal
ACS Central Science
Volume 8, Issue 4, Pages 449-460
Publisher
American Chemical Society (ACS)
Online
2022-03-18
DOI
10.1021/acscentsci.1c01479
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Note: Only part of the references are listed.- The role of vaccines in combatting antimicrobial resistance
- (2021) Francesca Micoli et al. NATURE REVIEWS MICROBIOLOGY
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- (2021) Marko Anderluh et al. FEBS Journal
- Human challenge study with a Shigella bioconjugate vaccine: Analyses of clinical efficacy and correlate of protection
- (2021) Kawsar R. Talaat et al. EBioMedicine
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- (2021) Debra McGuinness et al. VACCINE
- Impact of O-Acetylation on S. flexneri 1b and 2a O-Antigen Immunogenicity in Mice
- (2021) Vanessa Arato et al. Microorganisms
- Carbohydrate Conjugates in Vaccine Developments
- (2020) Shuyao Lang et al. Frontiers in Chemistry
- Improving efficacy of glycoconjugate vaccines: from chemical conjugates to next generation constructs
- (2020) Francesco Berti et al. CURRENT OPINION IN IMMUNOLOGY
- Expanding the role of bacterial vaccines into life-course vaccination strategies and prevention of antimicrobial-resistant infections
- (2020) Jan T. Poolman npj Vaccines
- Exploratory N‐protecting group manipulation for the total synthesis of zwitterionic Shigella sonnei oligosaccharides
- (2020) Debashis DHARA et al. CHEMISTRY-A EUROPEAN JOURNAL
- Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose-escalating, single-blind, randomised, placebo-controlled study
- (2020) Dani Cohen et al. LANCET INFECTIOUS DISEASES
- Serum IgG antibodies to Shigella lipopolysaccharide antigens – a correlate of protection against shigellosis
- (2019) Dani Cohen et al. Human Vaccines & Immunotherapeutics
- Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human
- (2019) Louis-Antoine Barel et al. Human Vaccines & Immunotherapeutics
- Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development
- (2019) Fikri Avci et al. mSphere
- Consensus Report on Shigella Controlled Human Infection Model: Clinical Endpoints
- (2019) Calman A MacLennan et al. CLINICAL INFECTIOUS DISEASES
- Shigellosis
- (2018) Karen L Kotloff et al. LANCET
- Role of O-Acetylation in the Immunogenicity of Bacterial Polysaccharide Vaccines
- (2018) Francesco Berti et al. MOLECULES
- The role of vaccines in preventing bacterial antimicrobial resistance
- (2018) Kathrin U Jansen et al. NATURE MEDICINE
- WHO consultation on ETEC and Shigella burden of disease, Geneva, 6–7th April 2017: Meeting report
- (2018) Divya Hosangadi et al. VACCINE
- Global disability-adjusted life-year estimates of long-term health burden and undernutrition attributable to diarrhoeal diseases in children younger than 5 years
- (2018) Christopher Troeger et al. Lancet Global Health
- Development, Interlaboratory Evaluations, and Application of a Simple, High-Throughput Shigella Serum Bactericidal Assay
- (2018) Moon H. Nahm et al. mSphere
- Bioconjugation with Maleimides: A useful Tool for Chemical Biology
- (2018) Pedro Miguel pimenta Gois et al. CHEMISTRY-A EUROPEAN JOURNAL
- Recent insights into Shigella
- (2018) Stephen Baker et al. CURRENT OPINION IN INFECTIOUS DISEASES
- Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990–2016
- (2018) Ibrahim A Khalil et al. LANCET INFECTIOUS DISEASES
- Glycoconjugate vaccines: Principles and mechanisms
- (2018) Rino Rappuoli Science Translational Medicine
- Polysaccharide structure dictates mechanism of adaptive immune response to glycoconjugate vaccines
- (2018) Ximei Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On the mechanisms of conjugate vaccines
- (2018) Rino Rappuoli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Travelers' Diarrhea: An Update on the Incidence, Etiology, and Risk in Military Deployments and Similar Travel Populations
- (2017) Chad K. Porter et al. MILITARY MEDICINE
- A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against Shigella sonnei Administered Intramuscularly to Adults from a Shigellosis-Endemic Country
- (2017) Christina W. Obiero et al. Frontiers in Immunology
- A Synthetic Carbohydrate Conjugate Vaccine Candidate against Shigellosis: Improved Bioconjugation and Impact of Alum on Immunogenicity
- (2016) Robert M. F. van der Put et al. BIOCONJUGATE CHEMISTRY
- Detailed Investigation of the Immunodominant Role of O-Antigen Stoichiometric O-Acetylation as Revealed by Chemical Synthesis, Immunochemistry, Solution Conformation and STD-NMR Spectroscopy for Shigella flexneri 3a
- (2016) Julien Boutet et al. CHEMISTRY-A EUROPEAN JOURNAL
- Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study
- (2016) Jie Liu et al. LANCET
- Programmed chemo-enzymatic synthesis of the oligosaccharide component of a carbohydrate-based antibacterial vaccine candidate
- (2015) Stéphane Salamone et al. CHEMICAL COMMUNICATIONS
- Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED)
- (2015) James A Platts-Mills et al. Lancet Global Health
- Chemical Biology Approaches to Designing Defined Carbohydrate Vaccines
- (2014) Chakkumkal Anish et al. CHEMISTRY & BIOLOGY
- Shigella Isolates From the Global Enteric Multicenter Study Inform Vaccine Development
- (2014) S. Livio et al. CLINICAL INFECTIOUS DISEASES
- Recent trends in the epidemiology of shigellosis in Israel
- (2014) D. COHEN et al. EPIDEMIOLOGY AND INFECTION
- Linear synthesis of the branched pentasaccharide repeats of O-antigens from Shigella flexneri 1a and 1b demonstrating the major steric hindrance associated with type-specific glucosylation
- (2014) Jason M. Hargreaves et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity
- (2014) Charles Gauthier et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Structural Studies of theO-Acetyl-Containing O-Antigen from aShigella flexneriSerotype 6 Strain and Synthesis of Oligosaccharide Fragments Thereof
- (2013) Pierre Chassagne et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- The history of pneumococcal conjugate vaccine development: dose selection
- (2013) Jan T Poolman et al. Expert Review of Vaccines
- Shigella flexneriO-antigens revisited: final elucidation of the O-acetylation profiles and a survey of the O-antigen structure diversity
- (2012) Andrei V. Perepelov et al. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
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- (2012) Ben-Quan Shen et al. NATURE BIOTECHNOLOGY
- Dynamic aspects of antibody:oligosaccharide complexes characterized by molecular dynamics simulations and saturation transfer difference nuclear magnetic resonance
- (2011) François-Xavier Theillet et al. GLYCOBIOLOGY
- Effects of backbone substitutions on the conformational behavior of Shigella flexneri O-antigens: implications for vaccine strategy
- (2010) François-Xavier Theillet et al. GLYCOBIOLOGY
- Age-related efficacy of Shigella O-specific polysaccharide conjugates in 1–4-year-old Israeli children
- (2010) Justen H. Passwell et al. VACCINE
- A similarity in the O-acetylation pattern of the O-antigens of Shigellaflexneri types 1a, 1b, and 2a
- (2009) Andrei V. Perepelov et al. CARBOHYDRATE RESEARCH
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- (2009) A. Phalipon et al. JOURNAL OF IMMUNOLOGY
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- Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody
- (2008) B. Vulliez-Le Normand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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