Programmed chemo-enzymatic synthesis of the oligosaccharide component of a carbohydrate-based antibacterial vaccine candidate

Chemical Biology Approaches to Designing Defined Carbohydrate Vaccines

(2014) Chakkumkal Anish et al.   CHEMISTRY & BIOLOGY

Shigella Isolates From the Global Enteric Multicenter Study Inform Vaccine Development

(2014) S. Livio et al.   CLINICAL INFECTIOUS DISEASES

Convergent Synthesis and Conformational Analysis of the Hexasaccharide Repeating Unit of theO-Antigen ofShigella flexneriSerotype 1d

(2014) Debashis Dhara et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Linear synthesis of the branched pentasaccharide repeats of O-antigens from Shigella flexneri 1a and 1b demonstrating the major steric hindrance associated with type-specific glucosylation

(2014) Jason M. Hargreaves et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity

(2014) Charles Gauthier et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

CGTase-Catalysedcis-Glucosylation ofL-Rhamnosides for the Preparation ofShigella flexneri2a and 3a Haptens

(2013) Carole Urbach et al.   CHEMBIOCHEM

Enzymatic Synthesis of Oligosaccharides: A Powerful Tool for a Sweet Challenge

(2013) Marco Filice et al.   CURRENT ORGANIC CHEMISTRY

Structural Studies of theO-Acetyl-Containing O-Antigen from aShigella flexneriSerotype 6 Strain and Synthesis of Oligo­saccharide Fragments Thereof

(2013) Pierre Chassagne et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Progress and pitfalls in Shigella vaccine research

(2013) Eileen M. Barry et al.   Nature Reviews Gastroenterology & Hepatology

A General Strategy for the Chemoenzymatic Synthesis of Asymmetrically Branched N-Glycans

(2013) Z. Wang et al.   SCIENCE

Shigella flexneriO-antigens revisited: final elucidation of the O-acetylation profiles and a survey of the O-antigen structure diversity

(2012) Andrei V. Perepelov et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Stereoselective Assembly of Complex Oligosaccharides Using Anomeric Sulfonium Ions as Glycosyl Donors

(2012) Tao Fang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Applying Pairwise Combinations of Amino Acid Mutations for Sorting Out Highly Efficient Glucosylation Tools for Chemo-Enzymatic Synthesis of Bacterial Oligosaccharides

(2012) Elise Champion et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward Automated Oligosaccharide Synthesis

(2011) Che-Hsiung Hsu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Do Glycosyl Sulfonium Ions Engage in Neighbouring-Group Participation? A Study of Oxathiane Glycosyl Donors and the Basis for their Stereoselectivity

(2011) Martin A. Fascione et al.   CHEMISTRY-A EUROPEAN JOURNAL

Carbohydrates and Immunology: Synthetic Oligosaccharide Antigens for Vaccine Formulation

(2011) Laura Morelli et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Glycosylation with glycosyl N-phenyltrifluoroacetimidates (PTFAI) and a perspective of the future development of new glycosylation methods

(2010) Biao Yu et al.   CHEMICAL COMMUNICATIONS

Effects of backbone substitutions on the conformational behavior of Shigella flexneri O-antigens: implications for vaccine strategy

(2010) François-Xavier Theillet et al.   GLYCOBIOLOGY

Carbohydrate vaccines: developing sweet solutions to sticky situations?

(2010) Rena D. Astronomo et al.   NATURE REVIEWS DRUG DISCOVERY

Comparative bioinformatics analysis of the mammalian and bacterial glycomes

(2010) Alexander Adibekian et al.   Chemical Science

New Principles for Glycoside-Bond Formation

(2009) Xiangming Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of dextrans with controlled amounts of α-1,2 linkages using the transglucosidase GBD–CD2

(2009) Yoann Brison et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Stereoselective glycosylation using oxathiane glycosyl donors

(2009) Martin A. Fascione et al.   CHEMICAL COMMUNICATIONS

A Synthetic Carbohydrate-Protein Conjugate Vaccine Candidate against Shigella flexneri 2a Infection

(2009) A. Phalipon et al.   JOURNAL OF IMMUNOLOGY

Efficient Synthesis of Six Tri- to Hexasaccharide Fragments ofShigella flexneriSerotypes 3a and/or X O-Antigen, Including a Study on Acceptors ContainingN-Trichloroacetylglucosamine versusN-Acetylglucosamine

(2009) Julien Boutet et al.   JOURNAL OF ORGANIC CHEMISTRY

Design of α-Transglucosidases of Controlled Specificity for Programmed Chemoenzymatic Synthesis of Antigenic Oligosaccharides

(2009) Elise Champion et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research

(2009) Thomas J. Boltje et al.   Nature Chemistry

Engineering the Glucansucrase GTFR Enzyme Reaction and Glycosidic Bond Specificity: Toward Tailor-Made Polymer and Oligosaccharide Products†

(2008) Hendrik Hellmuth et al.   BIOCHEMISTRY

Intramolecular aglycon delivery

(2008) Ian Cumpstey   CARBOHYDRATE RESEARCH

Synthesis of Two Tetra- and Four Pentasaccharide Fragments ofShigella flexneriSerotypes 3a and X O-Antigens from a Common Tetrasaccharide Intermediate

(2008) Julien Boutet et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of branched tri- to pentasaccharides representative of fragments of Shigella flexneri serotypes 3a and/or X O-antigens

(2008) Julien Boutet et al.   TETRAHEDRON