Impact of O-Acetylation on S. flexneri 1b and 2a O-Antigen Immunogenicity in Mice

Effect of O-Antigen Chain Length Regulation on the Immunogenicity of Shigella and Salmonella Generalized Modules for Membrane Antigens (GMMA)

(2021) Gianmarco Gasperini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stability of Outer Membrane Vesicles-Based Vaccines, Identifying the Most Appropriate Methods to Detect Changes in Vaccine Potency

(2021) Elena Palmieri et al.   Vaccines

Antibodies Elicited by the Shigella sonnei GMMA Vaccine in Adults Trigger Complement-Mediated Serum Bactericidal Activity: Results From a Phase 1 Dose Escalation Trial Followed by a Booster Extension

(2021) Francesca Micoli et al.   Frontiers in Immunology

Conformational and Immunogenicity Studies of the Shigella flexneri Serogroup 6 O-Antigen: The Effect of O-Acetylation

(2021) Nicole Inge Richardson et al.   Vaccines

Vaccines for Protecting Infants from Bacterial Causes of Diarrheal Disease

(2021) Richard Walker et al.   Microorganisms

Effects of Glucosylation and O-Acetylation on the Conformation of Shigella flexneri Serogroup 2 O-Antigen Vaccine Targets

(2020) Jason Hlozek et al.   JOURNAL OF PHYSICAL CHEMISTRY B

GMMA and Glycoconjugate Approaches Compared in Mice for the Development of a Vaccine against Shigella flexneri Serotype 6

(2020) Maria Michelina Raso et al.   Vaccines

Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human

(2019) Louis-Antoine Barel et al.   Human Vaccines & Immunotherapeutics

Responding to the challenge of antibiotic resistance: World Health Organization

(2018) SaurabhR Shrivastava et al.   Journal of Research in Medical Sciences

Role of O-Acetylation in the Immunogenicity of Bacterial Polysaccharide Vaccines

(2018) Francesco Berti et al.   MOLECULES

Emergence of antibiotic resistant Shigella species: A matter of concern

(2018) Minakshi Puzari et al.   Journal of Infection and Public Health

Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990–2016

(2018) Ibrahim A Khalil et al.   LANCET INFECTIOUS DISEASES

Effective protection of mice against Shigella flexneri with a new self-adjuvant multicomponent vaccine

(2017) Yadira Pastor et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Vaccination with Shigella flexneri 2a conjugate induces type 2a and cross-reactive type 6 antibodies in humans but not in mice

(2017) Nahid Farzam et al.   VACCINE

Characterization of O-antigen delivered by Generalized Modules for Membrane Antigens (GMMA) vaccine candidates against nontyphoidal Salmonella

(2017) G. De Benedetto et al.   VACCINE

A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against Shigella sonnei Administered Intramuscularly to Adults from a Shigellosis-Endemic Country

(2017) Christina W. Obiero et al.   Frontiers in Immunology

Safety Profile and Immunologic Responses of a Novel Vaccine Against Shigella sonnei Administered Intramuscularly, Intradermally and Intranasally: Results From Two Parallel Randomized Phase 1 Clinical Studies in Healthy Adult Volunteers in Europe

(2017) Odile Launay et al.   EBioMedicine

Development of a high-throughput method to evaluate serum bactericidal activity using bacterial ATP measurement as survival readout

(2017) Francesca Necchi et al.   PLoS One

Status of vaccine research and development for Shigella

(2016) Sachin Mani et al.   VACCINE

Characterization of a multicomponent live, attenuatedShigella flexnerivaccine

(2016) BreOnna C. DeLaine et al.   Pathogens and Disease

O-Antigen modifications providing antigenic diversity of Shigella flexneri and underlying genetic mechanisms

(2015) Y. A. Knirel et al.   BIOCHEMISTRY-MOSCOW

Genetic and structural identification of an O-acyltransferase gene (oacC) responsible for the 3/4-O-acetylation on rhamnose III in Shigella flexneri serotype 6

(2014) Yuriy A Knirel et al.   BMC MICROBIOLOGY

Identification of an O-Acyltransferase Gene (oacB) That Mediates 3- and 4-O-Acetylation of Rhamnose III in Shigella flexneri O Antigens

(2014) J. Wang et al.   JOURNAL OF BACTERIOLOGY

Serotype-Converting Bacteriophage SfII Encodes an Acyltransferase Protein That Mediates 6-O-Acetylation of GlcNAc in Shigella flexneri O-Antigens, Conferring on the Host a Novel O-Antigen Epitope

(2014) Q. Sun et al.   JOURNAL OF BACTERIOLOGY

Modulation of Endotoxicity ofShigellaGeneralized Modules for Membrane Antigens (GMMA) by Genetic Lipid A Modifications

(2014) Omar Rossi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity

(2014) Charles Gauthier et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structural analysis of O-polysaccharide chains extracted from different Salmonella Typhimurium strains

(2013) Francesca Micoli et al.   CARBOHYDRATE RESEARCH

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

Recent progress towards development of aShigellavaccine

(2012) Ana Isabel Camacho et al.   Expert Review of Vaccines

Shigella flexneriO-antigens revisited: final elucidation of the O-acetylation profiles and a survey of the O-antigen structure diversity

(2012) Andrei V. Perepelov et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

High Yield Production Process for Shigella Outer Membrane Particles

(2012) Francesco Berlanda Scorza et al.   PLoS One

Relevance of O-acetyl and phosphoglycerol groups for the antigenicity of Streptococcus pneumoniae serotype 18C capsular polysaccharide

(2012) Janoi Chang et al.   VACCINE