Bat Employs a Conserved MDA5 Gene to Trigger Antiviral Innate Immune Responses

Editorial: Host Innate Immune Responses to Infection by Avian- and Bat-Borne Viruses

(2021) Efstathios S. Giotis et al.   Frontiers in Cellular and Infection Microbiology

Distinct interferon response in bat and other mammalian cell lines infected with Pteropine orthoreovirus

(2021) Ronald Tarigan et al.   VIRUS GENES

Chicken DDX1 Acts as an RNA Sensor to Mediate IFN-β Signaling Pathway Activation in Antiviral Innate Immunity

(2021) Zhenyu Lin et al.   Frontiers in Immunology

A comprehensive profiling of innate immune responses in Eptesicus bat cells

(2021) Hsien‐Hen Lin et al.   MICROBIOLOGY AND IMMUNOLOGY

Post-COVID-19 Syndrome

(2021) Janet D. Pierce et al.   NURSING RESEARCH

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Pattern Recognition Receptor Signaling and Innate Responses to Influenza A Viruses in the Mallard Duck, Compared to Humans and Chickens

(2020) Lee K. Campbell et al.   Frontiers in Cellular and Infection Microbiology

Targeted Knockout of MDA5 and TLR3 in the DF-1 Chicken Fibroblast Cell Line Impairs Innate Immune Response Against RNA Ligands

(2020) Su Bin Lee et al.   Frontiers in Immunology

Role of pattern recognition receptors and interferon-beta in protecting bat cell lines from encephalomyocarditis virus and Japanese encephalitis virus infection

(2020) Ronald Tarigan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Detection of multiple viruses in oropharyngeal samples from Brazilian free-tailed bats (Tadarida brasiliensis) using viral metagenomics

(2020) Samuel Paulo Cibulski et al.   ARCHIVES OF VIROLOGY

SMART: recent updates, new developments and status in 2020

(2020) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

Cytokine Storm

(2020) David C. Fajgenbaum et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fundamental Characteristics of Bat Interferon Systems

(2020) Emily Clayton et al.   Frontiers in Cellular and Infection Microbiology

Viruses in bats and potential spillover to animals and humans

(2019) Lin-Fa Wang et al.   Current Opinion in Virology

IRF7 Is Involved in Both STING and MAVS Mediating IFN-β Signaling in IRF3-Lacking Chickens

(2019) Yuqiang Cheng et al.   JOURNAL OF IMMUNOLOGY

Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5

(2019) Morgan Brisse et al.   Frontiers in Immunology

Functional Characterization of Duck STING in IFN-β Induction and Anti-H9N2 Avian Influenza Viruses Infections

(2019) Yuqiang Cheng et al.   Frontiers in Immunology

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation

(2018) Antonio Gregorio Dias Junior et al.   TRENDS IN MICROBIOLOGY

The IFN Response in Bats Displays Distinctive IFN-Stimulated Gene Expression Kinetics with Atypical RNASEL Induction

(2017) Pamela C. De La Cruz-Rivera et al.   JOURNAL OF IMMUNOLOGY

Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus

(2017) S. J. Anthony et al.   mBio

Importance of Nucleic Acid Recognition in Inflammation and Autoimmunity

(2016) Franck J. Barrat et al.   Annual Review of Medicine

Antiviral function of grouper MDA5 against iridovirus and nodavirus

(2016) Youhua Huang et al.   FISH & SHELLFISH IMMUNOLOGY

Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

(2016) Emiko Uchikawa et al.   MOLECULAR CELL

Contraction of the type I IFN locus and unusual constitutive expression ofIFN-αin bats

(2016) Peng Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How RIG-I like receptors activate MAVS

(2015) Bin Wu et al.   Current Opinion in Virology

IRF7 in the Australian Black Flying Fox, Pteropus alecto: Evidence for a Unique Expression Pattern and Functional Conservation

(2014) Peng Zhou et al.   PLoS One

Melanoma Differentiation-Associated Gene 5 Senses Hepatitis B Virus and Activates Innate Immune Signaling To Suppress Virus Replication

(2013) H.-L. Lu et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of MAVS Regulation at the Mitochondrial Membrane

(2013) Jana L. Jacobs et al.   JOURNAL OF MOLECULAR BIOLOGY

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

(2013) Xing-Yi Ge et al.   NATURE

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

(2012) Ian C Berke et al.   EMBO JOURNAL

Comparative Analysis of Bat Genomes Provides Insight into the Evolution of Flight and Immunity

(2012) G. Zhang et al.   SCIENCE

Molecular characterisation of RIG-I-like helicases in the black flying fox, Pteropus alecto

(2011) Christopher Cowled et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Molecular characterisation of Toll-like receptors in the black flying fox Pteropus alecto

(2010) Christopher Cowled et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

RIG-I/MDA5/MAVS Are Required To Signal a Protective IFN Response in Rotavirus-Infected Intestinal Epithelium

(2010) A. H. Broquet et al.   JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Origin and evolution of the RIG-I like RNA helicase gene family

(2009) Jun Zou et al.   BMC EVOLUTIONARY BIOLOGY

Coronavirus Diversity, Phylogeny and Interspecies Jumping

(2009) Patrick C. Y. Woo et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Roosting ecology and variation in adaptive and innate immune system function in the Brazilian free-tailed bat (Tadarida brasiliensis)

(2008) Louise C. Allen et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY