MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA
Authors
Keywords
-
Journal
EMBO JOURNAL
Volume 31, Issue 7, Pages 1714-1726
Publisher
Wiley
Online
2012-02-07
DOI
10.1038/emboj.2012.19
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Structural Basis for the Activation of Innate Immune Pattern-Recognition Receptor RIG-I by Viral RNA
- (2011) Eva Kowalinski et al. CELL
- Structural Insights into RNA Recognition by RIG-I
- (2011) Dahai Luo et al. CELL
- MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response
- (2011) Fajian Hou et al. CELL
- RIG-I– and MDA5-Initiated Innate Immunity Linked With Adaptive Immunity Accelerates β-Cell Death in Fulminant Type 1 Diabetes
- (2011) Kaoru Aida et al. DIABETES
- Molecular Mechanism of Signal Perception and Integration by the Innate Immune Sensor Retinoic Acid-inducible Gene-I (RIG-I)
- (2011) Marco Binder et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Innate Immune Responses in Human Monocyte-Derived Dendritic Cells Are Highly Dependent on the Size and the 5' Phosphorylation of RNA Molecules
- (2011) M. Jiang et al. JOURNAL OF IMMUNOLOGY
- Structural basis of RNA recognition and activation by innate immune receptor RIG-I
- (2011) Fuguo Jiang et al. NATURE
- Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition
- (2011) A. Peisley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of the Drosophila Apoptosome at 6.9 Å Resolution
- (2011) Shujun Yuan et al. STRUCTURE
- Divergent Effects of Human Cytomegalovirus and Herpes Simplex Virus-1 on Cellular Metabolism
- (2011) Livia Vastag et al. PLoS Pathogens
- Crystal Structure of the Caenorhabditis elegans Apoptosome Reveals an Octameric Assembly of CED-4
- (2010) Shiqian Qi et al. CELL
- The FANCM family of DNA helicases/translocases
- (2010) Matthew C. Whitby DNA REPAIR
- Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling
- (2010) Su-Chang Lin et al. NATURE
- Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I
- (2010) Yanli Wang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5′ triphosphate
- (2010) Cheng Lu et al. NUCLEIC ACIDS RESEARCH
- LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
- (2010) T. Satoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain
- (2010) Cheng Lu et al. STRUCTURE
- Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5
- (2009) Xiaojun Li et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- On the analysis of sedimentation velocity in the study of protein complexes
- (2009) Patrick H. Brown et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus
- (2009) Martin Schlee et al. IMMUNITY
- DAMMIF, a program for rapidab-initioshape determination in small-angle scattering
- (2009) Daniel Franke et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Solution Structures of Cytosolic RNA Sensor MDA5 and LGP2 C-terminal Domains
- (2009) Kiyohiro Takahasi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Signal Transduction by Enzymatically Inactive Antiviral RNA Helicase Proteins MDA5, RIG-I, and LGP2
- (2009) Darja Bamming et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA
- (2009) Xiaojun Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection
- (2009) A. Pichlmair et al. JOURNAL OF VIROLOGY
- Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes
- (2009) S. Nejentsev et al. SCIENCE
- Translocation and Unwinding Mechanisms of RNA and DNA Helicases
- (2008) Anna Marie Pyle Annual Review of Biophysics
- A Malaria Parasite Formin Regulates Actin Polymerization and Localizes to the Parasite-Erythrocyte Moving Junction during Invasion
- (2008) Jake Baum et al. Cell Host & Microbe
- Agonist and Antagonist Recognition by RIG-I, a Cytoplasmic Innate Immunity Receptor
- (2008) C. T. Ranjith-Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure and Function of LGP2, a DEX(D/H) Helicase That Regulates the Innate Immunity Response
- (2008) Ayaluru Murali et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5
- (2008) Hiroki Kato et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mechanism of mda-5 Inhibition by Paramyxovirus V Proteins
- (2008) K. S. Childs et al. JOURNAL OF VIROLOGY
- The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I
- (2008) Sheng Cui et al. MOLECULAR CELL
- Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses
- (2008) Kiyohiro Takahasi et al. MOLECULAR CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search