An Overview of Autophagy in Helicobacter pylori Infection and Related Gastric Cancer

Identification of nafamostat mesylate as a selective stimulator of NK cell IFN-γ production via metabolism-related compound library screening

(2022) Qinglan Yang et al.   IMMUNOLOGIC RESEARCH

Crosstalk between autophagy and microbiota in cancer progression

(2021) Yu Wang et al.   Molecular Cancer

Targeting the Tumor Microenvironment: A Literature Review of the Novel Anti-Tumor Mechanism of Statins

(2021) Peng-Fei Zhu et al.   Frontiers in Oncology

Diverse roles of FOXO family members in gastric cancer

(2021) Yu-Han Chen et al.   World Journal of Gastrointestinal Oncology

MicroRNA-93-5p promotes epithelial-mesenchymal transition in gastric cancer by repressing tumor suppressor AHNAK expression

(2020) Erdong Shen et al.   Cancer Cell International

Helicobacter pylori promote inflammation and host defense through the cagA ‐dependent activation of mTORC1

(2020) Guang‐Jing Feng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effect of Astaxanthin on Activation of Autophagy and Inhibition of Apoptosis in Helicobacter pylori-Infected Gastric Epithelial Cell Line AGS

(2020) Hanbit Lee et al.   Nutrients

Inhibition of autophagy aggravates DNA damage response and gastric tumorigenesis via Rad51 ubiquitination in response to H. pylori infection

(2020) Chuan Xie et al.   Gut Microbes

PTEN, a Barrier for Proliferation and Metastasis of Gastric Cancer Cells: From Molecular Pathways to Targeting and Regulation

(2020) Milad Ashrafizadeh et al.   Biomedicines

Gastric cancer

(2020) Elizabeth C Smyth et al.   LANCET

A minireview: Role of AMP-activated protein kinase (AMPK) signaling in obesity-related renal injury

(2020) Zhuo Li et al.   LIFE SCIENCES

The Roles of Beclin 1 Expression in Gastric Cancer: A Marker for Carcinogenesis, Aggressive Behaviors and Favorable Prognosis, and a Target of Gene Therapy

(2020) Hua-chuan Zheng et al.   Frontiers in Oncology

Current information on the association of Helicobacter pylori with autophagy and gastric cancer

(2019) Majid Eslami et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nod1 imprints inflammatory and carcinogenic responses toward the gastric pathogen Helicobacter pylori

(2019) Giovanni Suarez et al.   CANCER RESEARCH

Clinically relevant concentrations of lidocaine inhibit tumor angiogenesis through suppressing VEGF/VEGFR2 signaling

(2019) Jin Gao et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Differential expression profile analysis of cisplatin‑regulated miRNAs in a human gastric cancer cell line

(2019) Chunlin Yin et al.   Molecular Medicine Reports

FOXP1-induced lncRNA CLRN1-AS1 acts as a tumor suppressor in pituitary prolactinoma by repressing the autophagy via inactivating Wnt/β-catenin signaling pathway

(2019) Chao Wang et al.   Cell Death & Disease

A Novel Role for Helicobacter pylori Gamma-Glutamyltranspeptidase in Regulating Autophagy and Bacterial Internalization in Human Gastric Cells

(2019) Jimena Bravo et al.   Cancers

Anti-angiogenesis triggers exosomes release from endothelial cells to promote tumor vasculogenesis

(2019) Ye Zeng et al.   Journal of Extracellular Vesicles

Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer

(2019) Jie Sun et al.   FEBS Journal

Molecular mechanism of Helicobacter�pylori‑induced autophagy in gastric cancer (Review)

(2019) Fan Zhang et al.   Oncology Letters

Molecular anatomy and pathogenic actions of Helicobacter pylori CagA that underpin gastric carcinogenesis

(2019) Atsushi Takahashi-Kanemitsu et al.   Cellular & Molecular Immunology

Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori

(2018) Lin Zhang et al.   JOURNAL OF PATHOLOGY

Risk of gastric cancer in association with Helicobacter pylori different virulence factors: A systematic review and meta-analysis

(2018) Ali pormohammad et al.   MICROBIAL PATHOGENESIS

LGR6 promotes the progression of gastric cancer through PI3K/AKT/mTOR pathway

(2018) Jing Ke et al.   OncoTargets and Therapy

Rapamycin Synergizes with Cisplatin in Antiendometrial Cancer Activation by Improving IL-27–Stimulated Cytotoxicity of NK Cells

(2018) Wen-Jie Zhou et al.   NEOPLASIA

Helicobacter pylori cholesterol glucosylation modulates autophagy for increasing intracellular survival in macrophages

(2018) Chih-Ho Lai et al.   CELLULAR MICROBIOLOGY

MicroRNA‑99b promotes Helicobacter pylori‑induced autophagyand suppresses carcinogenesis by targeting mTOR

(2018) Liu Yang et al.   Oncology Letters

Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway

(2018) Ho Lee et al.   Nutrients

Astaxanthin Inhibits Mitochondrial Dysfunction and Interleukin-8 Expression in Helicobacter pylori-Infected Gastric Epithelial Cells

(2018) Suhn Kim et al.   Nutrients

The VEGFR-2 protein and the VEGFR-2 rs1870377 A>T genetic polymorphism are prognostic factors for gastric cancer

(2018) Xueru Zhu et al.   CANCER BIOLOGY & THERAPY

Inflammasome activation and regulation during Helicobacter pylori pathogenesis

(2018) Sandeep Kumar et al.   MICROBIAL PATHOGENESIS

Autophagy impairment byHelicobacter pylori-induced methylation silencing ofMAP1LC3Av1promotes gastric carcinogenesis

(2017) Jibran Sualeh Muhammad et al.   INTERNATIONAL JOURNAL OF CANCER

Posttranscriptional Control of PD-L1 Expression by 17β-Estradiol via PI3K/Akt Signaling Pathway in ERα-Positive Cancer Cell Lines

(2017) Lingyun Yang et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Histone Deacetylase Inhibitors as Anticancer Drugs

(2017) Tomas Eckschlager et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA-28 promotes cell proliferation and invasion in gastric cancer via the PTEN/PI3K/AKT signalling pathway

(2017) Lihua Li et al.   Molecular Medicine Reports

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

(2017) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Health disparities are associated with gastric cancer mortality-to-incidence ratios in 57 countries

(2017) Ming-Chang Tsai et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Statin Decreases Helicobacter pylori Burden in Macrophages by Promoting Autophagy

(2017) Wei-Chih Liao et al.   Frontiers in Cellular and Infection Microbiology

Helicobacter pylori CagA Protein Negatively Regulates Autophagy and Promotes Inflammatory Response via c-Met-PI3K/Akt-mTOR Signaling Pathway

(2017) Na Li et al.   Frontiers in Cellular and Infection Microbiology

Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance

(2017) Alessandra Zingoni et al.   Frontiers in Immunology

Helicobacter pylori upregulates Nanog and Oct4 via Wnt/β-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer

(2016) Xin Yong et al.   CANCER LETTERS

Helicobacter pylori and Other Gastric Microbiota in Gastroduodenal Pathologies

(2016) Christian Schulz et al.   DIGESTIVE DISEASES

CagA-mediated pathogenesis of Helicobacter pylori

(2016) Abolghasem Tohidpour   MICROBIAL PATHOGENESIS

Relationship between VacA Toxin and Host Cell Autophagy in Helicobacter pylori Infection of the Human Stomach: A Few Answers, Many Questions

(2016) Vittorio Ricci   Toxins

The secreted antigen, HP0175, ofHelicobacter pylorilinks the unfolded protein response (UPR) to autophagy in gastric epithelial cells

(2015) Priyanka Halder et al.   CELLULAR MICROBIOLOGY

Detection of Helicobacter pylori CagA EPIYA in gastric biopsy specimens and its relation to gastric diseases

(2015) Júlia Silveira Vianna et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

The anti-malarial chloroquine suppresses proliferation and overcomes cisplatin resistance of endometrial cancer cells via autophagy inhibition

(2015) Tomohiko Fukuda et al.   GYNECOLOGIC ONCOLOGY

Analysis of the Relative Contribution of Phagocytosis, LC3-Associated Phagocytosis, and Canonical Autophagy DuringHelicobacter pyloriInfection of Macrophages

(2015) Nadia S. Deen et al.   HELICOBACTER

Autophagy inHelicobacter pyloriInfection and Related Gastric Cancer

(2015) Natalia Castaño-Rodríguez et al.   HELICOBACTER

CXCR7 mediates TGFβ1-promoted EMT and tumor-initiating features in lung cancer

(2015) Y-C Wu et al.   ONCOGENE

NOD1 and NOD2 Genetic Variants in Association with Risk of Gastric Cancer and Its Precursors in a Chinese Population

(2015) Zhe-Xuan Li et al.   PLoS One

Autophagy is involved in TGF-β1-induced protective mechanisms and formation of cancer-associated fibroblasts phenotype in tumor microenvironment

(2015) Fang-Lan Liu et al.   Oncotarget

Helicobacter pylori in gastric carcinogenesis

(2015) Hyo Jun Ahn et al.   World Journal of Gastrointestinal Oncology

Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis

(2014) Akimasa Takahashi et al.   Cancer Cell International

Global burden of gastric cancer attributable toHelicobacterpylori

(2014) Martyn Plummer et al.   INTERNATIONAL JOURNAL OF CANCER

Metformin Activates AMP-activated Protein Kinase by Promoting Formation of the αβγ Heterotrimeric Complex

(2014) Shumei Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation

(2014) C Kao et al.   Cell Death & Disease

The Role of Vimentin Intermediate Filaments in the Progression of Lung Cancer

(2013) Martha E Kidd et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

The impact of autophagic processes on the intracellular fate ofHelicobacter pylori

(2013) Nadia S. Deen et al.   Autophagy

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

Chaperone-mediated autophagy: roles in disease and aging

(2013) Ana Maria Cuervo et al.   CELL RESEARCH

Noncanonical autophagy: one small step for LC3, one giant leap for immunity

(2013) Payal Mehta et al.   CURRENT OPINION IN IMMUNOLOGY

Helicobacter pylori CagA and VacA genotypes and gastric phenotype

(2013) Joana I. Matos et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Catechins and Sialic Acid AttenuateHelicobacter pylori-Triggered Epithelial Caspase-1 Activity and EradicateHelicobacter pyloriInfection

(2013) Jyh-Chin Yang et al.   Evidence-based Complementary and Alternative Medicine

Autophagy: A critical regulator of cellular metabolism and homeostasis

(2013) Stefan W. Ryter et al.   MOLECULES AND CELLS

Repositioning metformin for cancer prevention and treatment

(2013) Brendan J. Quinn et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Modulation of autophagy by Helicobacter pylori and its role in gastric carcinogenesis

(2013) Laura K. Greenfield et al.   TRENDS IN MICROBIOLOGY

Autophagy: shaping the tumor microenvironment and therapeutic response

(2013) Hannelore Maes et al.   TRENDS IN MOLECULAR MEDICINE

Calcium-permeable ion channels in control of autophagy and cancer

(2013) Artem Kondratskyi   Frontiers in Physiology

Compromised autophagy byMIR30Bbenefits the intracellular survival ofHelicobacter pylori

(2012) Bin Tang et al.   Autophagy

Reactive Oxygen Species-Induced Autophagic Degradation of Helicobacter pylori CagA Is Specifically Suppressed in Cancer Stem-like Cells

(2012) Hitoshi Tsugawa et al.   Cell Host & Microbe

Vacuolating Cytotoxin and Variants in Atg16L1 That Disrupt Autophagy Promote Helicobacter pylori Infection in Humans

(2012) Deepa Raju et al.   GASTROENTEROLOGY

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Bortezomib induces G2-M arrest in human colon cancer cells through ROS-inducible phosphorylation of ATM-CHK1

(2012) Tae Kim   INTERNATIONAL JOURNAL OF ONCOLOGY

Low-density Lipoprotein Receptor-related Protein-1 (LRP1) Mediates Autophagy and Apoptosis Caused byHelicobacter pyloriVacA

(2012) Kinnosuke Yahiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens

(2012) Jun Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concordant repression and aberrant methylation of transforming growth factor-beta signaling pathway genes occurs early in gastric cardia adenocarcinoma

(2012) Wei Guo et al.   MOLECULAR BIOLOGY REPORTS

Chaperone-mediated autophagy: a unique way to enter the lysosome world

(2012) Susmita Kaushik et al.   TRENDS IN CELL BIOLOGY

Autophagy proteins in macroendocytic engulfment

(2012) Oliver Florey et al.   TRENDS IN CELL BIOLOGY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1

(2011) I. Ben Sahra et al.   CANCER RESEARCH

IFN-  Inhibits Gastric Carcinogenesis by Inducing Epithelial Cell Autophagy and T-Cell Apoptosis

(2011) S. P. Tu et al.   CANCER RESEARCH

Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives

(2011) D. Chen et al.   CURRENT CANCER DRUG TARGETS

Bortezomib represses HIF-1α protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells

(2011) Christina D. Befani et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

(2011) Oliver Florey et al.   NATURE CELL BIOLOGY

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress, and induces caspase-dependent cell death in antiestrogen–sensitive and resistant ER+ breast cancer cells

(2010) Sudharsan Periyasamy-Thandavan et al.   Autophagy

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

(2010) L. E. Wroblewski et al.   CLINICAL MICROBIOLOGY REVIEWS

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Mechanisms of disease: Helicobacter pylori virulence factors

(2010) Yoshio Yamaoka   Nature Reviews Gastroenterology & Hepatology

Pleiotropic Actions of Helicobacter pylori Vacuolating Cytotoxin, VacA

(2010) Hajime Isomoto et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

A new approach for the prevention and treatment ofHelicobacter pyloriinfection via upregulation of autophagy and downregulation of apoptosis

(2009) Jyh-Chin Yang et al.   Autophagy

Effect ofHelicobacter pylori’s vacuolating cytotoxin on the autophagy pathway in gastric epithelial cells

(2009) Mauricio R. Terebiznik et al.   Autophagy

Helicobacter pylori CagA Phosphorylation-Independent Function in Epithelial Proliferation and Inflammation

(2009) Masato Suzuki et al.   Cell Host & Microbe

Development of Inducible Systems To Engineer Conditional Mutants of Essential Genes of Helicobacter pylori

(2008) I. G. Boneca et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Protective effects of astaxanthin on 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells

(2008) Yasutaka Ikeda et al.   JOURNAL OF NEUROCHEMISTRY

Effective Prevention and Treatment of Helicobacter pylori Infection Using a Combination of Catechins and Sialic Acid in AGS Cells and BALB/c Mice

(2008) Jyh-Chin Yang et al.   JOURNAL OF NUTRITION

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL