Tyrosine Residue in the TRPV1 Vanilloid Binding Pocket Regulates Deactivation Kinetics

Capsaicin Interaction with TRPV1 Channels in a Lipid Bilayer: Molecular Dynamics Simulation

(2015) Sonya M. Hanson et al.   BIOPHYSICAL JOURNAL

Binding of Capsaicin to the TRPV1 Ion Channel

(2015) Leonardo Darré et al.   MOLECULAR PHARMACEUTICS

Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel

(2015) Fan Yang et al.   Nature Chemical Biology

Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin

(2015) Khaled Elokely et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pain receptor TRPV1 displays agonist-dependent activation stoichiometry

(2015) Adina Hazan et al.   Scientific Reports

Peripheral gating of pain signals by endogenous lipid mediators

(2014) Daniele Piomelli et al.   NATURE NEUROSCIENCE

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

Functionally Important Amino Acid Residues in the Transient Receptor Potential Vanilloid 1 (TRPV1) Ion Channel - An Overview of the Current Mutational Data

(2013) Zoltán Winter et al.   Molecular Pain

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain

(2010) Christopher J. Bohlen et al.   CELL

A “Cute” Desensitization of TRPV1

(2010) Filip Touska et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Conserved Residues within the Putative S4–S5 Region Serve Distinct Functions among Thermosensitive Vanilloid Transient Receptor Potential (TRPV) Channels

(2010) Stepana Boukalova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nociceptors: the sensors of the pain pathway

(2010) Adrienne E. Dubin et al.   JOURNAL OF CLINICAL INVESTIGATION

Modulation of single-channel properties of TRPV1 by phosphorylation

(2010) Milena Studer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Pharmacology of Vanilloid Transient Receptor Potential Cation Channels

(2009) J. Vriens et al.   MOLECULAR PHARMACOLOGY