Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel

Single particle electron cryo-microscopy of a mammalian ion channel

(2014) Maofu Liao et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Double electron–electron resonance reveals cAMP-induced conformational change in HCN channels

(2014) Michael C. Puljung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structural view of ligand-dependent activation in thermoTRP channels

(2014) Ximena Steinberg et al.   Frontiers in Physiology

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

Energetic analysis of the rhodopsin–G-protein complex links the α5 helix to GDP release

(2013) Nathan S Alexander et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism of Voltage Gating in Potassium Channels

(2012) M. O. Jensen et al.   SCIENCE

EM-Fold: De Novo Atomic-Detail Protein Structure Determination from Medium-Resolution Density Maps

(2012) Steffen Lindert et al.   STRUCTURE

The Effects of Capsaicin and Capsiate on Energy Balance: Critical Review and Meta-analyses of Studies in Humans

(2011) M.-J. Ludy et al.   CHEMICAL SENSES

Structure-Activity Relationship of Capsaicin Analogs and Transient Receptor Potential Vanilloid 1-Mediated Human Lung Epithelial Cell Toxicity

(2011) K. C. Thomas et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite

(2011) Sarel J. Fleishman et al.   PLoS One

Structural basis for gating charge movement in the voltage sensor of a sodium channel

(2011) V. Yarov-Yarovoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decrypting the Sequence of Structural Events during the Gating Transition of Pentameric Ligand-Gated Ion Channels Based on an Interpolated Elastic Network Model

(2011) Wenjun Zheng et al.   PLoS Computational Biology

Application of Hansch’s Model to Capsaicinoids and Capsinoids: A Study Using the Quantitative Structure−Activity Relationship. A Novel Method for the Synthesis of Capsinoids

(2010) Gerardo F. Barbero et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Conserved Residues within the Putative S4–S5 Region Serve Distinct Functions among Thermosensitive Vanilloid Transient Receptor Potential (TRPV) Channels

(2010) Stepana Boukalova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database

(2010) Paul C. D. Hawkins et al.   Journal of Chemical Information and Modeling

Thermosensitive TRP channel pore turret is part of the temperature activation pathway

(2010) F. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural determinants of gating in the TRPV1 channel

(2009) Héctor Salazar et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Blind docking of pharmaceutically relevant compounds using RosettaLigand

(2009) Ian W. Davis et al.   PROTEIN SCIENCE

RosettaLigand Docking with Full Ligand and Receptor Flexibility

(2008) Ian W. Davis et al.   JOURNAL OF MOLECULAR BIOLOGY