Disrupting the Allosteric Interaction between thePlasmodium falciparumcAMP-dependent Kinase and Its Regulatory Subunit
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Disrupting the Allosteric Interaction between thePlasmodium falciparumcAMP-dependent Kinase and Its Regulatory Subunit
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 291, Issue 49, Pages 25375-25386
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2016-10-14
DOI
10.1074/jbc.m116.750174
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of eighth biannual meeting (September 2015)
- (2016) MALARIA JOURNAL
- Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation
- (2016) Melissa J. Buskes et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Identification of Potent Phosphodiesterase Inhibitors that Demonstrate Cyclic Nucleotide-Dependent Functions in Apicomplexan Parasites
- (2015) Brittany L. Howard et al. ACS Chemical Biology
- Fitting two- and three-site binding models to isothermal titration calorimetric data
- (2015) Chad A. Brautigam METHODS
- Extensive differential protein phosphorylation as intraerythrocyticPlasmodium falciparumschizonts develop into extracellular invasive merozoites
- (2015) Edwin Lasonder et al. PROTEOMICS
- Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα
- (2015) Madoka Akimoto et al. PLOS BIOLOGY
- cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission
- (2015) Ghania Ramdani et al. PLoS Pathogens
- The Central Role of cAMP in Regulating Plasmodium falciparum Merozoite Invasion of Human Erythrocytes
- (2014) Amrita Dawn et al. PLoS Pathogens
- Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs
- (2013) Simon H. J. Brown et al. ACS Chemical Biology
- The Algal Past and Parasite Present of the Apicoplast
- (2013) Giel G. van Dooren et al. Annual Review of Microbiology
- Evolutionary Paths of the cAMP-Dependent Protein Kinase (PKA) Catalytic Subunits
- (2013) Kristoffer Søberg et al. PLoS One
- Signaling through dynamic linkers as revealed by PKA
- (2013) M. Akimoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PKA RIα Homodimer Structure Reveals an Intermolecular Interface with Implications for Cooperative cAMP Binding and Carney Complex Disease
- (2013) Jessica G.H. Bruystens et al. STRUCTURE
- Plasmodiumkinases as targets for new-generation antimalarials
- (2012) Isabelle S Lucet et al. Future Medicinal Chemistry
- The Plasmodium falciparum Schizont Phosphoproteome Reveals Extensive Phosphatidylinositol and cAMP-Protein Kinase A Signaling
- (2012) Edwin Lasonder et al. JOURNAL OF PROTEOME RESEARCH
- Exploring the Plasmodium falciparum cyclic-adenosine monophosphate (cAMP)-dependent protein kinase (PfPKA) as a therapeutic target
- (2012) Nina M. Haste et al. MICROBES AND INFECTION
- The role of cGMP signalling in regulating life cycle progression of Plasmodium
- (2012) Christine S. Hopp et al. MICROBES AND INFECTION
- Localization and quaternary structure of the PKA RI holoenzyme
- (2012) R. Ilouz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure and Allostery of the PKA RII Tetrameric Holoenzyme
- (2012) P. Zhang et al. SCIENCE
- Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum
- (2011) Lev Solyakov et al. Nature Communications
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design
- (2010) Suguna Badireddy et al. MOLECULAR & CELLULAR PROTEOMICS
- Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling
- (2010) Jimena Rinaldi et al. STRUCTURE
- Protein Kinase A Dependent Phosphorylation of Apical Membrane Antigen 1 Plays an Important Role in Erythrocyte Invasion by the Malaria Parasite
- (2010) Kerstin Leykauf et al. PLoS Pathogens
- Plasmodium falciparum Regulatory Subunit of cAMP-Dependent PKA and Anion Channel Conductance
- (2008) Anaïs Merckx et al. PLoS Pathogens
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started