Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation

Exploration of 3-methylisoquinoline-4-carbonitriles as protein kinase A inhibitors of Plasmodium falciparum

(2016) Melissa J. Buskes et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Insights and controversies into the role of the key apicomplexan invasion ligand, Apical Membrane Antigen 1

(2014) Katherine L. Harvey et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Kinase signalling in Plasmodium sexual stages and interventions to stop malaria transmission

(2014) Belinda Morahan et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Cell division in apicomplexan parasites

(2014) Maria E. Francia et al.   NATURE REVIEWS MICROBIOLOGY

Defining the biology component of the drug discovery strategy for malaria eradication

(2014) Didier Leroy et al.   TRENDS IN PARASITOLOGY

Antiparasitic Chemotherapy: From Genomes to Mechanisms

(2013) David Horn et al.   Annual Review of Pharmacology and Toxicology

An Automated Live Imaging Platform for Studying Merozoite Egress-Invasion in Malaria Cultures

(2013) Alex J. Crick et al.   BIOPHYSICAL JOURNAL

Malaria

(2013) Nicholas J White et al.   LANCET

Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

(2012) Mary P. Hall et al.   ACS Chemical Biology

The Plasmodium falciparum Schizont Phosphoproteome Reveals Extensive Phosphatidylinositol and cAMP-Protein Kinase A Signaling

(2012) Edwin Lasonder et al.   JOURNAL OF PROTEOME RESEARCH

A novel mechanism for egress of malarial parasites from red blood cells

(2011) M. Abkarian et al.   BLOOD

Two nucleus-localized CDK-like kinases with crucial roles for malaria parasite erythrocytic replication are involved in phosphorylation of splicing factor

(2011) Shruti Agarwal et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum

(2011) Lev Solyakov et al.   Nature Communications

In vitro efficacy of 7-benzylamino-1-isoquinolinamines against Plasmodium falciparum related to the efficacy of chalcones

(2010) Clare E. Gutteridge et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

An essential Aurora-related kinase transiently associates with spindle pole bodies during Plasmodium falciparum erythrocytic schizogony

(2010) Luc Reininger et al.   MOLECULAR MICROBIOLOGY

Protein Kinase A Dependent Phosphorylation of Apical Membrane Antigen 1 Plays an Important Role in Erythrocyte Invasion by the Malaria Parasite

(2010) Kerstin Leykauf et al.   PLoS Pathogens

Phenotypic and transcriptomic analyses of Plasmodium falciparum protein kinase A catalytic subunit inhibition

(2009) Nathalie Wurtz et al.   PARASITOLOGY RESEARCH

Rab11A-Controlled Assembly of the Inner Membrane Complex Is Required for Completion of Apicomplexan Cytokinesis

(2009) Carolina Agop-Nersesian et al.   PLoS Pathogens

Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites

(2008) Paul R. Gilson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Susceptibility of Plasmodium falciparum cyclic AMP-dependent protein kinase and its mammalian homologue to the inhibitors

(2008) Atsushi Sudo et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Plasmodium falciparum Regulatory Subunit of cAMP-Dependent PKA and Anion Channel Conductance

(2008) Anaïs Merckx et al.   PLoS Pathogens

Pharmacological PKA Inhibition: All May Not Be What It Seems

(2008) A. J. Murray   Science Signaling