The ZZ domain of HERC2 is a receptor of arginylated substrates

HERC2 inactivation abrogates nucleolar localization of RecQ helicases BLM and WRN

(2021) Mingzhang Zhu et al.   Scientific Reports

Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1

(2020) Jiuyang Liu et al.   STRUCTURE

ZZEF1 is a Histone Reader and Transcriptional Coregulator of Krüppel-Like Factors

(2020) Yucong Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

The ZZ domain as a new epigenetic reader and a degradation signal sensor

(2019) Yi Zhang et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3

(2018) Yi Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter

(2018) Do Hoon Kwon et al.   Nature Communications

The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation

(2018) Wenyi Mi et al.   Nature Communications

Inflammatory-dependent Sting activation induces antiviral autophagy to limit zika virus in the Drosophila brain

(2018) Elizabeth Delorme-Axford et al.   Autophagy

HERC2 Facilitates BLM and WRN Helicase Complex Interaction with RPA to Suppress G-Quadruplex DNA

(2018) Wenwen Wu et al.   CANCER RESEARCH

ZZ-dependent regulation of p62/SQSTM1 in autophagy

(2018) Yi Zhang et al.   Nature Communications

Accessibility of the histone H3 tail in the nucleosome for binding of paired readers

(2017) Jovylyn Gatchalian et al.   Nature Communications

p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis

(2017) Hyunjoo Cha-Molstad et al.   Nature Communications

Functional and pathological relevance of HERC family proteins: a decade later

(2016) Susana Sánchez-Tena et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

(2015) Hyunjoo Cha-Molstad et al.   NATURE CELL BIOLOGY

The Parkinson’s Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway

(2015) Yuzuru Imai et al.   PLoS Genetics

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

(2015) Joseph D Mancias et al.   eLife

HERC2 Targets the Iron Regulator FBXL5 for Degradation and Modulates Iron Metabolism

(2014) Toshiro Moroishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Degradation of the Deubiquitinating Enzyme USP33 Is Mediated by p97 and the Ubiquitin Ligase HERC2

(2014) Nickie C. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-End Rule Pathway

(2012) Takafumi Tasaki et al.   Annual Review of Biochemistry

DNA damage–inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

(2012) Jannie Rendtlew Danielsen et al.   JOURNAL OF CELL BIOLOGY

Interaction Proteomics Identify NEURL4 and the HECT E3 Ligase HERC2 as Novel Modulators of Centrosome Architecture

(2012) Abdallah K. Al-Hakim et al.   MOLECULAR & CELLULAR PROTEOMICS

HERC2 Interacts with Claspin and Regulates DNA Origin Firing and Replication Fork Progression

(2011) N. Izawa et al.   CANCER RESEARCH

The N-end rule pathway: emerging functions and molecular principles of substrate recognition

(2011) Shashikanth M. Sriram et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

HERC2 Is an E3 Ligase That Targets BRCA1 for Degradation

(2010) W. Wu et al.   CANCER RESEARCH

Structures of APC/CCdh1 with substrates identify Cdh1 and Apc10 as the D-box co-receptor

(2010) Paula C. A. da Fonseca et al.   NATURE

Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

(2010) T.-H. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA