Degradation of the Deubiquitinating Enzyme USP33 Is Mediated by p97 and the Ubiquitin Ligase HERC2

Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins

(2013) Nathan W. Pierce et al.   CELL

Deubiquitinases Sharpen Substrate Discrimination during Membrane Protein Degradation from the ER

(2013) Zai-Rong Zhang et al.   CELL

Evaluation and Optimization of Mass Spectrometric Settings during Data-dependent Acquisition Mode: Focus on LTQ-Orbitrap Mass Analyzers

(2013) Anastasia Kalli et al.   JOURNAL OF PROTEOME RESEARCH

USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110

(2013) Ji Li et al.   NATURE

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

(2013) Michal Simicek et al.   NATURE CELL BIOLOGY

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

(2013) Paola Magnaghi et al.   Nature Chemical Biology

Mutation of HERC2 causes developmental delay with Angelman-like features

(2012) Gaurav V Harlalka et al.   JOURNAL OF MEDICAL GENETICS

Alkylsulfanyl-1,2,4-triazoles, a New Class of Allosteric Valosine Containing Protein Inhibitors. Synthesis and Structure–Activity Relationships

(2012) Paolo Polucci et al.   JOURNAL OF MEDICINAL CHEMISTRY

Expanding into new markets – VCP/p97 in endocytosis and autophagy

(2012) Monika Bug et al.   JOURNAL OF STRUCTURAL BIOLOGY

Interaction Proteomics Identify NEURL4 and the HECT E3 Ligase HERC2 as Novel Modulators of Centrosome Architecture

(2012) Abdallah K. Al-Hakim et al.   MOLECULAR & CELLULAR PROTEOMICS

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

(2012) Hemmo Meyer et al.   NATURE CELL BIOLOGY

Update on activities at the Universal Protein Resource (UniProt) in 2013

(2012)   NUCLEIC ACIDS RESEARCH

Coordinated regulation of XPA stability by ATR and HERC2 during nucleotide excision repair

(2012) T-H Lee et al.   ONCOGENE

Growing sphere of influence: Cdc48/p97 orchestrates ubiquitin-dependent extraction from chromatin

(2012) Nico P. Dantuma et al.   TRENDS IN CELL BIOLOGY

Regulation of p97 in the ubiquitin–proteasome system by the UBX protein-family

(2011) Patrik Kloppsteck et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

(2011) Nickie C. Chan et al.   HUMAN MOLECULAR GENETICS

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Isoform-Specific Localization of the Deubiquitinase USP33 to the Golgi Apparatus

(2011) Christopher Thorne et al.   TRAFFIC

Cdc48: a power machine in protein degradation

(2011) Alexandra Stolz et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Cdc48–Ufd1–Npl4 complex is central in ubiquitin–proteasome triggered catabolite degradation of fructose-1,6-bisphosphatase

(2010) Lise Barbin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HERC2 Is an E3 Ligase That Targets BRCA1 for Degradation

(2010) W. Wu et al.   CANCER RESEARCH

The p97 ATPase Dislocates MHC Class I Heavy Chain in US2-expressing Cells via a Ufd1-Npl4-independent Mechanism

(2010) Nia Soetandyo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover

(2010) Shan Xu et al.   MOLECULAR BIOLOGY OF THE CELL

A Stress-Responsive System for Mitochondrial Protein Degradation

(2010) Jin-Mi Heo et al.   MOLECULAR CELL

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

The deubiquitinases USP33 and USP20 coordinate β2 adrenergic receptor recycling and resensitization

(2009) Magali Berthouze et al.   EMBO JOURNAL

Ubx4 Modulates Cdc48 Activity and Influences Degradation of Misfolded Proteins of the Endoplasmic Reticulum

(2009) Sven M. Alberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

(2009) Simon Bekker-Jensen et al.   NATURE CELL BIOLOGY

Midline crossing and Slit responsiveness of commissural axons require USP33

(2009) Junichi Yuasa-Kawada et al.   NATURE NEUROSCIENCE

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration

(2009) J. Yuasa-Kawada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into adaptor binding to the AAA protein p97

(2008) Heidi O. Yeung et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The RCC1 superfamily: From genes, to function, to disease

(2008) Ouadah Hadjebi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

(2008) C. Schuberth et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY