Upregulated NLRP3 inflammasome activation is attenuated by anthocyanins in patients with nonalcoholic fatty liver disease: A case-control and an intervention study

Pathogenetic mechanisms of nonalcoholic fatty liver disease and inhibition of the inflammasome as a new therapeutic target

(2021) Yasar Colak et al.   Clinics and Research in Hepatology and Gastroenterology

Long‐term outcomes of non‐alcoholic fatty liver disease and the risk factors for mortality and hepatocellular carcinoma in a Japanese population

(2020) Tomomi Kogiso et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

A dose-response evaluation of purified anthocyanins on inflammatory and oxidative biomarkers and metabolic risk factors in healthy young adults: A randomized controlled trial

(2020) Yi Guo et al.   NUTRITION

Anthocyanin supplementation improves anti-oxidative and anti-inflammatory capacity in a dose–response manner in subjects with dyslipidemia

(2020) Hanyue Zhang et al.   Redox Biology

FibroScan-AST (FAST) score for the non-invasive identification of patients with non-alcoholic steatohepatitis with significant activity and fibrosis: a prospective derivation and global validation study

(2020) Philip N Newsome et al.   Lancet Gastroenterology & Hepatology

Anthocyanin supplementation at different doses improves cholesterol efflux capacity in subjects with dyslipidemia—a randomized controlled trial

(2020) Zhongliang Xu et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Inhibitory effects of phytochemicals on NLRP3 inflammasome activation: A review

(2020) Melis Olcum et al.   PHYTOMEDICINE

Synthetic vitamin K analogs inhibit inflammation by targeting the NLRP3 inflammasome

(2020) Xicui Zheng et al.   Cellular & Molecular Immunology

Inhibition of Interleukin-1β and Reduction in Atherothrombotic Cardiovascular Events in the CANTOS Trial

(2020) Brendan M. Everett et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The selective NLRP3 inflammasome inhibitor MCC950 alleviates cholestatic liver injury and fibrosis in mice

(2019) Junwen Qu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The antiobesity effects of anthocyanins on mitochondrial biogenesis, inflammation and oxidative stress: A systematic review

(2019) Gomes Jaqueline Vieira Piovezana et al.   NUTRITION

Obesity-related inflammatory modulation by juçara berry (Euterpe edulis Mart.) supplementation in Brazilian adults: a double-blind randomized controlled trial

(2019) Aline Boveto Santamarina et al.   EUROPEAN JOURNAL OF NUTRITION

Anthocyanins ameliorate palmitate‐induced inflammation and insulin resistance in 3T3‐L1 adipocytes

(2019) Claudia Muscarà et al.   PHYTOTHERAPY RESEARCH

Anthocyanin supplementation inhibits secretion of pro-inflammatory cytokines in overweight and obese individuals

(2019) Lada Vugic et al.   Journal of Functional Foods

Current and future therapeutic regimens for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2018) Zobair M. Younossi et al.   HEPATOLOGY

Anthocyanin-Rich Extract from Red Chinese Cabbage Alleviates Vascular Inflammation in Endothelial Cells and Apo E−/− Mice

(2018) Hee Joo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice

(2018) Bing Xu et al.   JOURNAL OF HEPATOLOGY

Red raspberries suppress NLRP3 inflammasome and attenuate metabolic abnormalities in diet-induced obese mice

(2018) Mei-Jun Zhu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Global Perspectives on Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis

(2018) Zobair Younossi et al.   HEPATOLOGY

Anthocyanins As Modulators of Cell Redox-Dependent Pathways in Non-Communicable Diseases

(2018) Antonio Speciale et al.   CURRENT MEDICINAL CHEMISTRY

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

(2017) Auvro R. Mridha et al.   JOURNAL OF HEPATOLOGY

Black soybean anthocyanins attenuate inflammatory responses by suppressing reactive oxygen species production and mitogen activated protein kinases signaling in lipopolysaccharide-stimulated macrophages

(2017) Jin Nam Kim et al.   Nutrition Research and Practice

Role of Purified Anthocyanins in Improving Cardiometabolic Risk Factors in Chinese Men and Women with Prediabetes or Early Untreated Diabetes—A Randomized Controlled Trial

(2017) Liping Yang et al.   Nutrients

Differences in metabolic biomarkers in the blood and gene expression profiles of peripheral blood mononuclear cells among normal weight, mildly obese and moderately obese subjects

(2016) Un Ju Jung et al.   BRITISH JOURNAL OF NUTRITION

Fish-oil-derived n-3 polyunsaturated fatty acids reduce NLRP3 inflammasome activity and obesity-related inflammatory cross-talk between adipocytes and CD11b+ macrophages

(2016) Anna A. De Boer et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Chemistry, Pharmacology and Health Benefits of Anthocyanins

(2016) Antonella Smeriglio et al.   PHYTOTHERAPY RESEARCH

Role of NLRP3 Inflammasome in the Progression of NAFLD to NASH

(2016) Xingyong Wan et al.   Canadian Journal of Gastroenterology and Hepatology

A CONSORT-Compliant, Randomized, Double-Blind, Placebo-Controlled Pilot Trial of Purified Anthocyanin in Patients With Nonalcoholic Fatty Liver Disease

(2015) Pei-Wen Zhang et al.   MEDICINE

ZJU index: a novel model for predicting nonalcoholic fatty liver disease in a Chinese population

(2015) Jinghua Wang et al.   Scientific Reports

NLRP3 inflammasome activation is required for fibrosis development in NAFLD

(2014) Alexander Wree et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

(2012) Hye-Mi Lee et al.   DIABETES

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE