Interaction of tumor cells with the microenvironment

TGF-β Signaling in Breast Cancer Cell Invasion and Bone Metastasis

(2011) Yvette Drabsch et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Extracellular signals in young and aging breast epithelial cells and possible connections to age-associated breast cancer development

(2011) Sukhada Chaturvedi et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1

(2011) Hendrik Ungefroren et al.   Molecular Cancer

Intravital Imaging Illuminates Transforming Growth Factor β Signaling Switches during Metastasis

(2010) Silvia Giampieri et al.   CANCER RESEARCH

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

The role of the tissue microenvironment in the regulation of cancer cell motility and invasion

(2010) Jan Brábek et al.   Cell Communication and Signaling

Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12

(2010) Antonella Rigo et al.   Molecular Cancer

Epithelial-Mesenchymal Transition

(2009) Michael W. Klymkowsky et al.   AMERICAN JOURNAL OF PATHOLOGY

Epidermal growth factor receptor regulates pancreatic fibrosis

(2009) Stacy A. Blaine et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The complete family of epidermal growth factor receptors and their ligands are co-ordinately expressed in breast cancer

(2009) Emmet McIntyre et al.   BREAST CANCER RESEARCH AND TREATMENT

Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor  1- and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer

(2009) C. Geismann et al.   CANCER RESEARCH

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

(2009) T. Arumugam et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

An atypical NF-kappa B-regulated pathway mediates phorbol ester-dependent Heme oxygenase-1 gene activation in monocytes

(2009) S Naidu et al.   Cell Communication and Signaling

Lysyl oxidase as a potential therapeutic target

(2009) C. Rodríguez et al.   DRUG NEWS & PERSPECTIVES

Targeting the transforming growth factor-β signaling pathway in human cancer

(2009) Nagathihalli S Nagaraj et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis

(2009) X. Lu et al.   GENES & DEVELOPMENT

Gene Expression Analysis of Macrophages That Facilitate Tumor Invasion Supports a Role for Wnt-Signaling in Mediating Their Activity in Primary Mammary Tumors

(2009) L. S. Ojalvo et al.   JOURNAL OF IMMUNOLOGY

Functional plasticity of macrophages: in situ reprogramming of tumor-associated macrophages

(2009) Robert D. Stout et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer

(2009) Hiroshi Kurahara et al.   JOURNAL OF SURGICAL RESEARCH

Cellular senescence of human mammary epithelial cells (HMEC) is associated with an altered MMP-7/HB-EGF signaling and increased formation of elastin-like structures

(2009) Catharina Bertram et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Collective cell migration in morphogenesis, regeneration and cancer

(2009) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression

(2009) Masayuki Shimoda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Transforming growth factor-β signaling: emerging stem cell target in metastatic breast cancer?

(2008) Antoinette R. Tan et al.   BREAST CANCER RESEARCH AND TREATMENT

Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence

(2008) Stéphane Ansieau et al.   CANCER CELL

The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance

(2008) Paola Allavena et al.   IMMUNOLOGICAL REVIEWS

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark