Valosin-containing protein and neurofibromin interact to regulate dendritic spine density

Multiple increased osteoclast functions in individuals with neurofibromatosis type 1

(2011) David A. Stevenson et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

ESCRT, autophagy, and frontotemporal dementia

(2011) Jin-A Lee et al.   BMB Reports

Primary osteopathy of vertebrae in a neurofibromatosis type 1 murine model

(2011) Wei Zhang et al.   BONE

Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1

(2011) S. Rumpf et al.   DEVELOPMENT

Neurofibromin (Nf1) is required for skeletal muscle development

(2011) Nadine Kossler et al.   HUMAN MOLECULAR GENETICS

p97/VCP at the intersection of the autophagy and the ubiquitin proteasome system

(2010) Jeong-Sun Ju et al.   Autophagy

VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

(2010) Emilie Tresse et al.   Autophagy

Bone resorption in syndromes of the Ras/MAPK pathway

(2010) DA Stevenson et al.   CLINICAL GENETICS

A novel ATP-dependent conformation in p97 N–D1 fragment revealed by crystal structures of disease-related mutants

(2010) Wai Kwan Tang et al.   EMBO JOURNAL

Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone

(2010) Sara K. Custer et al.   HUMAN MOLECULAR GENETICS

Sterol-induced Dislocation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Endoplasmic Reticulum Membranes into the Cytosol through a Subcellular Compartment Resembling Lipid Droplets

(2010) Isamu Z. Hartman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts

(2010) Weixi Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

CHMP2B mutants linked to frontotemporal dementia impair maturation of dendritic spines

(2010) A. Belly et al.   JOURNAL OF CELL SCIENCE

Synapse loss in dementias

(2010) Ryan Clare et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

(2010) Janel O. Johnson et al.   NEURON

VCP Associated Inclusion Body Myopathy and Paget Disease of Bone Knock-In Mouse Model Exhibits Tissue Pathology Typical of Human Disease

(2010) Mallikarjun Badadani et al.   PLoS One

Characterisation of the interaction between syndecan-2, neurofibromin and CASK: Dependence of interaction on syndecan dimerization

(2009) Manuela Volta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

(2009) Jeong-Sun Ju et al.   JOURNAL OF CELL BIOLOGY

Hereditary Inclusion Body Myopathy-Linked p97/VCP Mutations in the NH2 Domain and the D1 Ring Modulate p97/VCP ATPase Activity and D2 Ring Conformation

(2009) D. Halawani et al.   MOLECULAR AND CELLULAR BIOLOGY

Dislocation of HMG-CoA Reductase and Insig-1, Two Polytopic Endoplasmic Reticulum Proteins, En Route to Proteasomal Degradation

(2009) Gil S. Leichner et al.   MOLECULAR BIOLOGY OF THE CELL

Neurofibromin physically interacts with the N-terminal domain of focal adhesion kinase

(2009) Frederick Kweh et al.   MOLECULAR CARCINOGENESIS

Clinical studies in familial VCP myopathy associated with Paget disease of bone and frontotemporal dementia

(2008) Virginia. E. Kimonis et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Neurofibromin interacts with CRMP-2 and CRMP-4 in rat brain

(2008) Yi-Ling Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Roles of VCP in human neurodegenerative disorders

(2008) Akira Kakizuka   BIOCHEMICAL SOCIETY TRANSACTIONS

Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin

(2008) Mateusz Kolanczyk et al.   BMC Medicine

Effect of Simvastatin on Cognitive Functioning in Children With Neurofibromatosis Type 1

(2008) Lianne C. Krab   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neurofibromatosis Type 1 (NF1) Tumor Suppressor, Neurofibromin, Regulates the Neuronal Differentiation of PC12 Cells via Its Associating Protein, CRMP-2

(2008) Siriporn Patrakitkomjorn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMOylation of the MAGUK protein CASK regulates dendritic spinogenesis

(2008) Hsu-Wen Chao et al.   JOURNAL OF CELL BIOLOGY

AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential

(2008) Neeraj Vij   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Neurofibromin Is Required for Barrel Formation in the Mouse Somatosensory Cortex

(2008) M. E. Lush et al.   JOURNAL OF NEUROSCIENCE

NS21: Re-defined and modified supplement B27 for neuronal cultures

(2008) Yucui Chen et al.   JOURNAL OF NEUROSCIENCE METHODS