NF1germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1

Elucidating the impact of neurofibromatosis-1 germline mutations on neurofibromin function and dopamine-based learning

(2015) C. Anastasaki et al.   HUMAN MOLECULAR GENETICS

High Incidence of Noonan Syndrome Features Including Short Stature and Pulmonic Stenosis in Patients carrying NF1 Missense Mutations Affecting p.Arg1809: Genotype-Phenotype Correlation

(2015) Kitiwan Rojnueangnit et al.   HUMAN MUTATION

Optic glioma and precocious puberty in a girl with neurofibromatosis type 1 carrying an R681X mutation of NF1: case report and review of the literature

(2015) Mirjana Kocova et al.   BMC Endocrine Disorders

RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth

(2015) Anne C. Solga et al.   NEOPLASIA

CCL5 promotes VEGF-dependent angiogenesis by down-regulating miR-200b through PI3K/Akt signaling pathway in human chondrosarcoma cells

(2015) Guan-Ting Liu et al.   Oncotarget

The Cyclic AMP Pathway Is a Sex-Specific Modifier of Glioma Risk in Type I Neurofibromatosis Patients

(2014) N. M. Warrington et al.   CANCER RESEARCH

p.Arg1809Cys substitution in neurofibromin is associated with a distinctive NF1 phenotype without neurofibromas

(2014) Valentina Pinna et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A Novel Mouse Model of a Patient Mucolipidosis II Mutation Recapitulates Disease Pathology

(2014) Leigh Paton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of coexisting genetic mutations on murine optic glioma biology

(2014) Aparna Kaul et al.   NEURO-ONCOLOGY

Akt- or MEK-mediated mTOR inhibition suppresses Nf1 optic glioma growth

(2014) Aparna Kaul et al.   NEURO-ONCOLOGY

K-RasV14Irecapitulates Noonan syndrome in mice

(2014) Isabel Hernández-Porras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumors

(2014) Jacquelyn J. Roth et al.   Cancer Genetics

Sex Is a major determinant of neuronal dysfunction in neurofibromatosis type 1

(2013) Kelly A. Diggs-Andrews et al.   ANNALS OF NEUROLOGY

Myocardial KRASG12D expression does not cause cardiomyopathy in mice

(2013) Martin G. Dalin et al.   CARDIOVASCULAR RESEARCH

NG2-cells are not the cell of origin for murine neurofibromatosis-1 (Nf1) optic glioma

(2013) A C Solga et al.   ONCOGENE

Reduced microglial CX3CR1 expression delays neurofibromatosis-1 glioma formation

(2012) Winnie W. Pong et al.   ANNALS OF NEUROLOGY

Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis

(2012) M. J. Fisher et al.   NEURO-ONCOLOGY

Retinal Nerve Fiber Layer Thickness in Children With Optic Pathway Gliomas

(2011) Robert A. Avery et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer

(2011) E E Vincent et al.   BRITISH JOURNAL OF CANCER

A molecular analysis of individuals with neurofibromatosis type 1 (NF1) and optic pathway gliomas (OPGs), and an assessment of genotype-phenotype correlations

(2011) S. Sharif et al.   JOURNAL OF MEDICAL GENETICS

Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner

(2010) D. Y. Lee et al.   GENES & DEVELOPMENT

Clinical and genetic aspects of neurofibromatosis 1

(2010) Kimberly Jett et al.   GENETICS IN MEDICINE

Neurofibromatosis-1 Heterozygosity Increases Microglia in a Spatially and Temporally Restricted Pattern Relevant to Mouse Optic Glioma Formation and Growth

(2010) Grant W. Simmons et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Defective cAMP Generation Underlies the Sensitivity of CNS Neurons to Neurofibromatosis-1 Heterozygosity

(2010) J. A. Brown et al.   JOURNAL OF NEUROSCIENCE

Unravelling the genetic basis of variable clinical expression in neurofibromatosis 1

(2009) Audrey Sabbagh et al.   HUMAN MOLECULAR GENETICS

Clinical and Mutational Spectrum of Neurofibromatosis Type 1–like Syndrome

(2009) Ludwine Messiaen   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Optic Nerve Dysfunction in a Mouse Model of Neurofibromatosis-1 Optic Glioma

(2009) Balazs Hegedus et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Time-course of the retinal nerve fibre layer degeneration after complete intra-orbital optic nerve transection or crush: A comparative study

(2009) Guillermo Parrilla-Reverter et al.   VISION RESEARCH

CCL5 increases lung cancer migration via PI3K, Akt and NF-κB pathways

(2008) Chun-Yin Huang et al.   BIOCHEMICAL PHARMACOLOGY

Increased c-Jun-NH2-Kinase Signaling in Neurofibromatosis-1 Heterozygous Microglia Drives Microglia Activation and Promotes Optic Glioma Proliferation

(2008) G. C. Daginakatte et al.   CANCER RESEARCH

Preclinical Cancer Therapy in a Mouse Model of Neurofibromatosis-1 Optic Glioma

(2008) B. Hegedus et al.   CANCER RESEARCH