Structural basis for modulation of human NaV1.3 by clinical drug and selective antagonist

Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin

(2021) Daohua Jiang et al.   Nature Communications

Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Nav1.5 by the Antiarrhythmic Drug Quinidine

(2021) Zhangqiang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Open-state structure and pore gating mechanism of the cardiac sodium channel

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Structural Basis for High-Affinity Trapping of the NaV1.7 Channel in Its Resting State by Tarantula Toxin

(2020) Goragot Wisedchaisri et al.   MOLECULAR CELL

Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA

(2019) Xiaojing Pan et al.   SCIENCE

Structural basis of α-scorpion toxin action on Nav channels

(2019) Thomas Clairfeuille et al.   SCIENCE

Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins

(2019) Huaizong Shen et al.   SCIENCE

Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel

(2019) Goragot Wisedchaisri et al.   CELL

Structure of the Cardiac Sodium Channel

(2019) Daohua Jiang et al.   CELL

Mutations in SCN3A cause early infantile epileptic encephalopathy

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cisTEM, user-friendly software for single-particle image processing

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Sodium Channel SCN3A (NaV1.3) Regulation of Human Cerebral Cortical Folding and Oral Motor Development

(2018) Richard S. Smith et al.   NEURON

Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1

(2018) Xiaojing Pan et al.   SCIENCE

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

(2018) Huaizong Shen et al.   SCIENCE

New tools for automated high-resolution cryo-EM structure determination in RELION-3

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The chemical basis for electrical signaling

(2017) William A Catterall et al.   Nature Chemical Biology

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

SCN3A deficiency associated with increased seizure susceptibility

(2017) Tyra Lamar et al.   NEUROBIOLOGY OF DISEASE

The pharmacology of voltage-gated sodium channel activators

(2017) Jennifer R. Deuis et al.   NEUROPHARMACOLOGY

Structures of closed and open states of a voltage-gated sodium channel

(2017) Michael J. Lenaeus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Putting the squeeze on superconductivity

(2017) Kyle M. Shen   SCIENCE

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist

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Novel SCN3A variants associated with focal epilepsy in children

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Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels

(2013) K. McCormack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels

(2011) Marijke Stevens et al.   Frontiers in Pharmacology

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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Inherited Neuronal Ion Channelopathies: New Windows on Complex Neurological Diseases

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