Open-state structure and pore gating mechanism of the cardiac sodium channel

Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin

(2021) Daohua Jiang et al.   Nature Communications

Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA

(2019) Xiaojing Pan et al.   SCIENCE

Structural basis of α-scorpion toxin action on Nav channels

(2019) Thomas Clairfeuille et al.   SCIENCE

Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins

(2019) Huaizong Shen et al.   SCIENCE

Structural basis for antiarrhythmic drug interactions with the human cardiac sodium channel

(2019) Phuong T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel

(2019) Goragot Wisedchaisri et al.   CELL

Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels

(2019) William A. Catterall et al.   Annual Review of Pharmacology and Toxicology

Structure of the Cardiac Sodium Channel

(2019) Daohua Jiang et al.   CELL

Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1

(2018) Xiaojing Pan et al.   SCIENCE

CHARMM-GUI Membrane Builder for Complex Biological Membrane Simulations with Glycolipids and Lipoglycans

(2018) Jumin Lee et al.   Journal of Chemical Theory and Computation

Fenestrations control resting-state block of a voltage-gated sodium channel

(2018) Tamer M. Gamal El-Din et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Structures of closed and open states of a voltage-gated sodium channel

(2017) Michael J. Lenaeus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

(2016) Jing Huang et al.   NATURE METHODS

MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories

(2015) Robert T. McGibbon et al.   BIOPHYSICAL JOURNAL

CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field

(2015) Jumin Lee et al.   Journal of Chemical Theory and Computation

The hitchhiker’s guide to the voltage-gated sodium channel galaxy

(2015) Christopher A. Ahern et al.   JOURNAL OF GENERAL PHYSIOLOGY

Hydrophobic Gating in Ion Channels

(2015) Prafulla Aryal et al.   JOURNAL OF MOLECULAR BIOLOGY

Hydrophobic Gating of Ion Permeation in Magnesium Channel CorA

(2015) Chris Neale et al.   PLoS Computational Biology

CHARMM-GUIMembrane Buildertoward realistic biological membrane simulations

(2014) Emilia L. Wu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Local anesthetic and antiepileptic drug access and binding to a bacterial voltage-gated sodium channel

(2014) C. Boiteux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ion conduction and conformational flexibility of a bacterial voltage-gated sodium channel

(2014) Céline Boiteux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels

(2013) Deborah L. Capes et al.   JOURNAL OF GENERAL PHYSIOLOGY

Simulations of Anionic Lipid Membranes: Development of Interaction-Specific Ion Parameters and Validation Using NMR Data

(2013) Richard M. Venable et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

OPM database and PPM web server: resources for positioning of proteins in membranes

(2011) Mikhail A. Lomize et al.   NUCLEIC ACIDS RESEARCH

Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels

(2011) Stephan A. Pless et al.   Nature Communications

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes

(2009) Sunhwan Jo et al.   BIOPHYSICAL JOURNAL

Control of Ion Selectivity in LeuT: Two Na+ Binding Sites with Two Different Mechanisms

(2008) Sergei Y. Noskov et al.   JOURNAL OF MOLECULAR BIOLOGY

P-LINCS:  A Parallel Linear Constraint Solver for Molecular Simulation

(2007) Berk Hess   Journal of Chemical Theory and Computation