GSH‐Responsive Metal–Organic Framework for Intratumoral Release of NO and IDO Inhibitor to Enhance Antitumor Immunotherapy

From Design to Clinic: Engineered Nanobiomaterials for Immune Normalization Therapy of Cancer

(2021) Madiha Saeed et al.   ADVANCED MATERIALS

Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy

(2021) Jimin Zhang et al.   Bioactive Materials

Engineering Stimuli‐Activatable Boolean Logic Prodrug Nanoparticles for Combination Cancer Immunotherapy

(2020) Bo Hou et al.   ADVANCED MATERIALS

A Nitric Oxide (NO) Nanoreporter for Noninvasive Real‐Time Imaging of Macrophage Immunotherapy

(2020) Anujan Ramesh et al.   ADVANCED MATERIALS

Redox Responsive Metal Organic Framework Nanoparticles Induces Ferroptosis for Cancer Therapy

(2020) Haozhe He et al.   Small

Tumors and Their Microenvironment Dual‐Targeting Chemotherapy with Local Immune Adjuvant Therapy for Effective Antitumor Immunity against Breast Cancer

(2019) Caifeng Deng et al.   Advanced Science

Immunomodulatory roles of nitric oxide in cancer: tumour microenvironment says “NO” to anti-tumour immune response

(2019) Jon Peñarando et al.   Translational Research

Nanoscale Coordination Polymers for Synergistic NO and Chemodynamic Therapy of Liver Cancer

(2019) Yihui Hu et al.   NANO LETTERS

Poly(amidoamine) Dendrimer-Coordinated Copper(II) Complexes as a Theranostic Nanoplatform for the Radiotherapy-Enhanced Magnetic Resonance Imaging and Chemotherapy of Tumors and Tumor Metastasis

(2019) Yu Fan et al.   NANO LETTERS

Revisiting IDO and its value as a predictive marker for anti-PD-1 resistance

(2019) Peter Kim Moon et al.   Journal of Translational Medicine

Hypoxia alleviation-triggered enhanced photodynamic therapy in combination with IDO inhibitor for preferable cancer therapy

(2019) Lei Xing et al.   BIOMATERIALS

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

(2019) Fangyuan Zhou et al.   ADVANCED MATERIALS

Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours

(2019) Han Yao et al.   Nature Biomedical Engineering

Organic Semiconducting Pro-nanostimulants for Near-Infrared Photoactivatable Cancer Immunotherapy

(2019) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Developing neoantigen-targeted T cell–based treatments for solid tumors

(2019) Tori N. Yamamoto et al.   NATURE MEDICINE

Metabolomic adaptations and correlates of survival to immune checkpoint blockade

(2019) Haoxin Li et al.   Nature Communications

Defective Porous Carbon Polyhedra Decorated with Copper Nanoparticles for Enhanced NIR‐Driven Photothermal Cancer Therapy

(2019) Yangziwan Weng et al.   Small

Repurposing Cyanine NIR-I Dyes Accelerates Clinical Translation of Near-Infrared-II (NIR-II) Bioimaging

(2018) Shoujun Zhu et al.   ADVANCED MATERIALS

High IDO-1 expression in tumor endothelial cells is associated with response to immunotherapy in metastatic renal cell carcinoma

(2018) Andreas Seeber et al.   CANCER SCIENCE

Recent discovery of indoleamine-2,3-dioxygenase 1 inhibitors targeting cancer immunotherapy

(2018) Tianwei Weng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IDO expression in breast cancer: an assessment of 281 primary and metastatic cases with comparison to PD-L1

(2018) Erik A. Dill et al.   MODERN PATHOLOGY

Sequentially Responsive Therapeutic Peptide Assembling Nanoparticles for Dual-Targeted Cancer Immunotherapy

(2018) Keman Cheng et al.   NANO LETTERS

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

(2018) Joseph A. Fraietta et al.   NATURE MEDICINE

Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy

(2018) Jinrong Peng et al.   Advanced Science

Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab

(2018) Anders H. Kverneland et al.   OncoImmunology

Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy

(2018) Kuangda Lu et al.   Nature Biomedical Engineering

Covalent Organic Polymers Based on Fluorinated Porphyrin as Oxygen Nanoshuttles for Tumor Hypoxia Relief and Enhanced Photodynamic Therapy

(2018) Danlei Tao et al.   ADVANCED FUNCTIONAL MATERIALS

Toward Biomaterials for Enhancing Immune Checkpoint Blockade Therapy

(2018) Qin Fan et al.   ADVANCED FUNCTIONAL MATERIALS

Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment

(2018) Bing Feng et al.   ADVANCED MATERIALS

Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway

(2018) Jianqin Lu et al.   ACS Nano

Tuning secondary building unit of Cu-BTC to simultaneously enhance its CO2 selective adsorption and stability under moisture

(2018) Yufang Wu et al.   CHEMICAL ENGINEERING JOURNAL

Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan–Kynurenine–Aryl Hydrocarbon Axis

(2018) Brian W. Labadie et al.   CLINICAL CANCER RESEARCH

Efficient Near Infrared Light Triggered Nitric Oxide Release Nanocomposites for Sensitizing Mild Photothermal Therapy

(2018) Xiao Zhang et al.   Advanced Science

Near-Infrared Polymeric Nanoparticles with High Content of Cyanine for Bimodal Imaging and Photothermal Therapy

(2016) Wenhai Lin et al.   ACS Applied Materials & Interfaces

Cu(II) doped polyaniline nanoshuttles for multimodal tumor diagnosis and therapy

(2016) Min Lin et al.   BIOMATERIALS

Emerging concepts of T cell metabolism as a target of immunotherapy

(2016) Chih-Hao Chang et al.   NATURE IMMUNOLOGY

Designer vaccine nanodiscs for personalized cancer immunotherapy

(2016) Rui Kuai et al.   NATURE MATERIALS

Controllable Generation of Nitric Oxide by Near-Infrared-Sensitized Upconversion Nanoparticles for Tumor Therapy

(2015) Xiao Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Facile Conversion of Hydroxy Double Salts to Metal–Organic Frameworks Using Metal Oxide Particles and Atomic Layer Deposition Thin-Film Templates

(2015) Junjie Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A novel self-assembled sandwich nanomedicine for NIR-responsive release of NO

(2015) Jing Fan et al.   Nanoscale

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Targeting the indoleamine 2,3-dioxygenase pathway in cancer

(2015) Yong Wha Moon et al.   Journal for ImmunoTherapy of Cancer

The link between infection and cancer: Tumor vasculature, free radicals, and drug delivery to tumors via the EPR effect

(2013) Hiroshi Maeda   CANCER SCIENCE

Cancer Immunotherapy

(2013) J. Couzin-Frankel   SCIENCE

Nitric oxide and cancer: a review

(2013) Sheetal Korde Choudhari et al.   World Journal of Surgical Oncology

Immunotherapy of cancer in 2012

(2012) John M. Kirkwood et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

(2012) L. Pilotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of melanoma tumor-derived nitric oxide in the tumor inflammatory microenvironment: Its impact on the chemokine expression profile, including suppression of CXCL10

(2011) Keiji Tanese et al.   INTERNATIONAL JOURNAL OF CANCER

Complex Inhibitory Effects of Nitric Oxide on Autophagy

(2011) Sovan Sarkar et al.   MOLECULAR CELL