The link between infection and cancer: Tumor vasculature, free radicals, and drug delivery to tumors via the EPR effect

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

Inflammation-mediated genomic instability: roles of activation-induced cytidine deaminase in carcinogenesis

(2012) Takahiro Shimizu et al.   CANCER SCIENCE

Discovery and therapeutic potential of kinin receptor antagonists

(2012) Eric T Whalley et al.   Expert Opinion on Drug Discovery

Kinin receptors as targets for cancer therapy

(2012) Carlos D Figueroa et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Macromolecular therapeutics in cancer treatment: The EPR effect and beyond

(2012) Hiroshi Maeda   JOURNAL OF CONTROLLED RELEASE

Micelles of zinc protoporphyrin conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer for imaging and light-induced antitumor effects in vivo

(2012) Hideaki Nakamura et al.   JOURNAL OF CONTROLLED RELEASE

Guided delivery of polymer therapeutics using plasmonic photothermal therapy

(2012) Adam J. Gormley et al.   Nano Today

Vascular permeability in cancer and infection as related to macromolecular drug delivery, with emphasis on the EPR effect for tumor-selective drug targeting

(2012) Hiroshi MAEDA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Theranostics: Combining Imaging and Therapy

(2011) Sneha S. Kelkar et al.   BIOCONJUGATE CHEMISTRY

Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors

(2011) Jun Fang et al.   CANCER SCIENCE

Intracellular uptake and behavior of two types zinc protoporphyrin (ZnPP) micelles, SMA-ZnPP and PEG-ZnPP as anticancer agents; unique intracellular disintegration of SMA micelles

(2011) Hideaki Nakamura et al.   JOURNAL OF CONTROLLED RELEASE

Tumour necrosis factor-alpha increases extravasation of virus particles into tumour tissue by activating the Rho A/Rho kinase pathway

(2011) Takahiro Seki et al.   JOURNAL OF CONTROLLED RELEASE

Nanomedicine(s) under the Microscope

(2011) Ruth Duncan et al.   MOLECULAR PHARMACEUTICS

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects

(2010) Hiroshi Maeda   BIOCONJUGATE CHEMISTRY

In vitro and in vivo evaluation of tumor targeting styrene-maleic acid copolymer-pirarubicin micelles: Survival improvement and inhibition of liver metastases

(2010) Jurstine Daruwalla et al.   CANCER SCIENCE

Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application

(2009) Takahiro Seki et al.   CANCER SCIENCE

Elevating Blood Pressure as a Strategy to Increase Tumor-targeted Delivery of Macromolecular Drug SMANCS: Cases of Advanced Solid Tumors

(2009) Akinori Nagamitsu et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Generation of drug-resistant mutants ofHelicobacter pyloriin the presence of peroxynitrite, a derivative of nitric oxide, at pathophysiological concentration

(2009) Hideo Kuwahara et al.   MICROBIOLOGY AND IMMUNOLOGY

Styrene Maleic Acid-Pirarubicin Disrupts Tumor Microcirculation and Enhances the Permeability of Colorectal Liver Metastases

(2008) Jurstine Daruwalla et al.   JOURNAL OF VASCULAR RESEARCH