Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy

Biodegradable Nanoscale Coordination Polymers for Targeted Tumor Combination Therapy with Oxidative Stress Amplification

(2020) Jingjing Liu et al.   ADVANCED FUNCTIONAL MATERIALS

On Supramolecular Self‐Assembly: Interview with Samuel Stupp

(2020) Samuel I. Stupp   ADVANCED MATERIALS

Light-Switchable Yolk-Mesoporous Shell UCNPs@MgSiO3 for Nitric Oxide-Evoked Multidrug Resistance Reversal in Cancer Therapy

(2020) Shihua Li et al.   ACS Applied Materials & Interfaces

Cancer cell therapies: the clinical trial landscape

(2020) Jia Xin Yu et al.   NATURE REVIEWS DRUG DISCOVERY

ATP Suppression by pH-Activated Mitochondria-Targeted Delivery of Nitric Oxide Nanoplatform for Drug Resistance Reversal and Metastasis Inhibition

(2020) Yongyan Deng et al.   Small

Supramolecular Tubustecan Hydrogel as Chemotherapeutic Carrier to Improve Tumor Penetration and Local Treatment Efficacy

(2020) Feihu Wang et al.   ACS Nano

Enzymatically Formed Peptide Assemblies Sequestrate Proteins and Relocate Inhibitors to Selectively Kill Cancer Cells

(2020) Hongjian He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trap and kill strategy for non-BRCA mutant pancreatic cancer by co-delivery of olaparib and JQ1 with plectin-1 targeting peptide nanoparticles

(2020) Yazhou Wang et al.   Nano Today

Bioinspired Nanofibrous Glycopeptide Hydrogel Dressing for Accelerating Wound Healing: A Cytokine‐Free, M2‐Type Macrophage Polarization Approach

(2020) Zujian Feng et al.   ADVANCED FUNCTIONAL MATERIALS

Synthetic macromolecules as therapeutics that overcome resistance in cancer and microbial infection

(2020) Jason Tan et al.   BIOMATERIALS

Cascade of reactive oxygen species generation by polyprodrug for combinational photodynamic therapy

(2020) Zujian Feng et al.   BIOMATERIALS

Cocktail polyprodrug nanoparticles concurrently release cisplatin and peroxynitrite-generating nitric oxide in cisplatin-resistant cancers

(2020) Chengyan Chu et al.   CHEMICAL ENGINEERING JOURNAL

Bio-inspired nitric-oxide-driven nanomotor

(2019) Mimi Wan et al.   Nature Communications

Supramolecular Nanofibers with Superior Bioactivity to Insulin-Like Growth Factor-I

(2019) Yuna Shang et al.   NANO LETTERS

Enzyme‐Instructed Self‐Assembly (EISA) and Hydrogelation of Peptides

(2019) Jie Gao et al.   ADVANCED MATERIALS

Dysoxylactam A: A Macrocyclolipopeptide Reverses P-Glycoprotein-Mediated Multidrug Resistance in Cancer Cells

(2019) Cui-Ping Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Metal–Polyphenol‐Coordinated Nanomedicine for Synergistic Cascade Cancer Chemotherapy and Chemodynamic Therapy

(2019) Zhigang Ren et al.   ADVANCED MATERIALS

Mitochondrial dysfunction, autophagy stimulation and non-apoptotic cell death caused by nitric oxide-inducing Pt-coated Au nanoparticle in human lung carcinoma cells

(2019) Mohd Javed Akhtar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cooperative Assembly of a Peptide Gelator and Silk Fibroin Afford an Injectable Hydrogel for Tissue Engineering

(2018) Baochang Cheng et al.   ACS Applied Materials & Interfaces

Supramolecular Nanofibers of Curcumin for Highly Amplified Radiosensitization of Colorectal Cancers to Ionizing Radiation

(2018) Huae Xu et al.   ADVANCED FUNCTIONAL MATERIALS

A Structural View on Medicinal Chemistry Strategies against Drug Resistance

(2018) Stefano Agnello et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stimuli-Responsive NO Release for On-Demand Gas-Sensitized Synergistic Cancer Therapy

(2018) Wenpei Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoparticle-assisted ultrasound: A special focus on sonodynamic therapy against cancer

(2018) Giancarlo Canavese et al.   CHEMICAL ENGINEERING JOURNAL

Engineering Dendritic-Cell-Based Vaccines and PD-1 Blockade in Self-Assembled Peptide Nanofibrous Hydrogel to Amplify Antitumor T-Cell Immunity

(2018) Pengxiang Yang et al.   NANO LETTERS

NO prodrug-conjugated, self-assembled, pH-responsive and galactose receptor targeted nanoparticles for co-delivery of nitric oxide and doxorubicin

(2018) Jimin Zhang et al.   Nanoscale

Glutathione-induced amino-activatable micellar photosensitization platform for synergistic redox modulation and photodynamic therapy

(2018) Ruiwei Guo et al.   Biomaterials Science

Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reaction

(2018) Zhongmin Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nitric oxide as an all-rounder for enhanced photodynamic therapy: Hypoxia relief, glutathione depletion and reactive nitrogen species generation

(2018) Yongyan Deng et al.   BIOMATERIALS

JS-K as a nitric oxide donor induces apoptosis via the ROS/Ca2+/caspase-mediated mitochondrial pathway in HepG2 cells

(2018) Zile Huang et al.   BIOMEDICINE & PHARMACOTHERAPY

Peptide supramolecular materials for therapeutics

(2018) Kohei Sato et al.   CHEMICAL SOCIETY REVIEWS

Instructed Assembly of Peptides for Intracellular Enzyme Sequestration

(2018) Zhaoqianqi Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted delivery of nitric oxide via a ‘bump-and-hole’-based enzyme–prodrug pair

(2018) Jingli Hou et al.   Nature Chemical Biology

Combination of nitric oxide and drug delivery systems: tools for overcoming drug resistance in chemotherapy

(2017) Jihoon Kim et al.   JOURNAL OF CONTROLLED RELEASE

Nitric Oxide Donor-Based Cancer Therapy: Advances and Prospects

(2017) Zhangjian Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Light-Responsive Biodegradable Nanomedicine Overcomes Multidrug Resistance via NO-Enhanced Chemosensitization

(2016) Jing Fan et al.   ACS Applied Materials & Interfaces

Activatable Photosensitizers: Agents for Selective Photodynamic Therapy

(2016) Xingshu Li et al.   ADVANCED FUNCTIONAL MATERIALS

Novel anticancer oridonin derivatives possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Design, synthesis, biological evaluation and nitric oxide release studies

(2016) Shengtao Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Controllable Generation of Nitric Oxide by Near-Infrared-Sensitized Upconversion Nanoparticles for Tumor Therapy

(2015) Xiao Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Enzyme-Instructed Intracellular Molecular Self-Assembly to Boost Activity of Cisplatin against Drug-Resistant Ovarian Cancer Cells

(2015) Jie Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nitric Oxide Releasing d-α-Tocopheryl Polyethylene Glycol Succinate for Enhancing Antitumor Activity of Doxorubicin

(2014) Qingle Song et al.   MOLECULAR PHARMACEUTICS

Site-directed delivery of nitric oxide to cancers

(2014) Kavita Sharma et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Co-delivery of chemotherapeutic drugs with vitamin E TPGS by porous PLGA nanoparticles for enhanced chemotherapy against multi-drug resistance

(2013) Huijun Zhu et al.   BIOMATERIALS

Hybrid Molecule from O2-(2,4-Dinitrophenyl)diazeniumdiolate and Oleanolic Acid: A Glutathione S-Transferase π-Activated Nitric Oxide Prodrug with Selective Anti-Human Hepatocellular Carcinoma Activity and Improved Stability

(2013) Junjie Fu et al.   JOURNAL OF MEDICINAL CHEMISTRY

BODIPY dyes in photodynamic therapy

(2012) Anyanee Kamkaew et al.   CHEMICAL SOCIETY REVIEWS

Co-delivery of siRNA and therapeutic agents using nanocarriers to overcome cancer resistance

(2012) Mar Creixell et al.   Nano Today

Versatile Small-Molecule Motifs for Self-Assembly in Water and the Formation of Biofunctional Supramolecular Hydrogels

(2010) Ye Zhang et al.   LANGMUIR

Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles

(2009) Xiang Rong Song et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Squaraine dyes: a mine of molecular materials

(2007) Sivaramapanicker Sreejith et al.   JOURNAL OF MATERIALS CHEMISTRY