Seminars in cell and development biology on histone variants remodelers of H2A variants associated with heterochromatin

The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome

(2021) Maud De Dieuleveult et al.   Epigenetics

Histone variants at a glance

(2021) Paul B. Talbert et al.   JOURNAL OF CELL SCIENCE

The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A.W

(2021) Akihisa Osakabe et al.   NATURE CELL BIOLOGY

The epiallelic potential of transposable elements and its evolutionary significance in plants

(2021) Pierre Baduel et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The histone variant H2A.W and linker histone H1 co-regulate heterochromatin accessibility and DNA methylation

(2021) Pierre Bourguet et al.   Nature Communications

Lymphoid-specific helicase in epigenetics, DNA repair and cancer

(2021) Xiangyu Chen et al.   BRITISH JOURNAL OF CANCER

Histone variants take center stage in shaping the epigenome

(2021) Michael Borg et al.   CURRENT OPINION IN PLANT BIOLOGY

MacroH2A1.2 deficiency leads to neural stem cell differentiation defects and autism‐like behaviors

(2021) Hongyan Ma et al.   EMBO REPORTS

Systemic depletion of histone macroH2A1.1 boosts hippocampal synaptic plasticity and social behavior in mice

(2021) Valentina Chiodi et al.   FASEB JOURNAL

LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2

(2021) Kai Ni et al.   NUCLEIC ACIDS RESEARCH

The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation

(2021) Xiaoping Xu et al.   Nature Communications

Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice

(2021) Sanghyun P. Kim et al.   Cell Reports

The Role of MacroH2A Histone Variants in Cancer

(2021) Chen-Jen Hsu et al.   Cancers

Histone H1 prevents non-CG methylation-mediated small RNA biogenesis in Arabidopsis heterochromatin

(2021) Jaemyung Choi et al.   eLife

The ZBTB24-CDCA7 axis regulates HELLS enrichment at centromeric satellite repeats to facilitate DNA methylation

(2020) Swanand Hardikar et al.   Protein & Cell

The roles of histone variants in fine-tuning chromatin organization and function

(2020) Sara Martire et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination

(2020) Yafeng He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Silencing and Transcriptional Regulation of Endogenous Retroviruses: An Overview

(2020) Franziska K. Geis et al.   Viruses-Basel

Epigenetic regulation of spurious transcription initiation in Arabidopsis

(2020) Ngoc Tu Le et al.   Nature Communications

A Synthetic Approach to Reconstruct the Evolutionary and Functional Innovations of the Plant Histone Variant H2A.W

(2020) Bingkun Lei et al.   CURRENT BIOLOGY

Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome

(2020) Angela Helfricht et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis

(2020) Claudia Baumann et al.   Nature Communications

CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats

(2020) Motoko Unoki et al.   Scientific Reports

PRDM9 activity depends on HELLS and promotes local 5-hydroxymethylcytosine enrichment

(2020) Yukiko Imai et al.   eLife

Remodeler Catalyzed Nucleosome Repositioning: Influence of Structure and Stability

(2020) Aaron Morgan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mutation in DDM1 inhibits the homology directed repair of double strand breaks

(2019) Seung Hee Choi et al.   PLoS One

The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors

(2019) Jianke Ren et al.   Epigenetics

Histone variant macroH2A: from chromatin deposition to molecular function

(2019) Zhen Sun et al.   Essays in Biochemistry

Structural basis of specific DNA binding by the transcription factor ZBTB24

(2019) Ren Ren et al.   NUCLEIC ACIDS RESEARCH

Transposition favors the generation of large effect mutations that may facilitate rapid adaption

(2019) Leandro Quadrana et al.   Nature Communications

Host–transposon interactions: conflict, cooperation, and cooption

(2019) Rachel L Cosby et al.   GENES & DEVELOPMENT

Role of Mammalian DNA Methyltransferases in Development

(2019) Zhiyuan Chen et al.   Annual Review of Biochemistry

INO80 and SWR1 complexes: the non-identical twins of chromatin remodelling

(2019) Oliver Willhoft et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes

(2018) Jianke Ren et al.   Epigenetics

Comparative methylome analysis of ICF patients identifies heterochromatin loci that require ZBTB24, CDCA7 and HELLS for their methylated state

(2018) Guillaume Velasco et al.   HUMAN MOLECULAR GENETICS

Subtelomeric methylation distinguishes between subtypes of Immunodeficiency, Centromeric Instability and Facial Anomalies (ICF) syndrome

(2018) Shir Toubiana et al.   HUMAN MOLECULAR GENETICS

Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions

(2018) Jeongkyu Kim et al.   MOLECULAR CELL

Dynamics and function of DNA methylation in plants

(2018) Huiming Zhang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone H2A variants confer specific properties to nucleosomes and impact on chromatin accessibility

(2018) Akihisa Osakabe et al.   NUCLEIC ACIDS RESEARCH

OUP accepted manuscript

(2018)   NUCLEIC ACIDS RESEARCH

DDM1 guards against telomere truncation in Arabidopsis

(2018) Xiaoyuan Xie et al.   PLANT CELL REPORTS

HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome

(2018) Christopher Jenness et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic insights into histone deposition and nucleosome assembly by the chromatin assembly factor-1

(2018) Paul V Sauer et al.   NUCLEIC ACIDS RESEARCH

CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome

(2018) Motoko Unoki et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitative resistance to clubroot infection mediated by transgenerational epigenetic variation in Arabidopsis

(2018) Benjamin Liégard et al.   NEW PHYTOLOGIST

Molecular Processes Connecting DNA Methylation Patterns with DNA Methyltransferases and Histone Modifications in Mammalian Genomes

(2018) Albert Jeltsch et al.   Genes

Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes

(2017) Cedric R. Clapier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Variants of core histones and their roles in cell fate decisions, development and cancer

(2017) Marcus Buschbeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transposable elements (TEs) contribute to stress-related long intergenic noncoding RNAs in plants

(2017) Dong Wang et al.   PLANT JOURNAL

Decrease in Lymphoid Specific Helicase and 5-hydroxymethylcytosine Is Associated with Metastasis and Genome Instability

(2017) Jiantao Jia et al.   Theranostics

DDM1 and Lsh remodelers allow methylation of DNA wrapped in nucleosomes

(2017) David B Lyons et al.   eLife

Heterochromatin and DNA damage repair: Use different histone variants and relax

(2017) Zdravko J. Lorković et al.   Nucleus

Heterochromatin and DNA damage repair: Use different histone variants and relax

(2017) Zdravko J. Lorković et al.   Nucleus

Lsh/HELLS regulates self-renewal/proliferation of neural stem/progenitor cells

(2017) Yixing Han et al.   Scientific Reports

Mechanisms of ATP-Dependent Chromatin Remodeling Motors

(2016) Coral Y. Zhou et al.   Annual Review of Biophysics

Converging disease genes in ICF syndrome:ZBTB24controls expression ofCDCA7in mammals

(2016) Haoyu Wu et al.   HUMAN MOLECULAR GENETICS

Genetic, Cellular and Clinical Features of ICF Syndrome: a French National Survey

(2016) Delphine Sterlin et al.   JOURNAL OF CLINICAL IMMUNOLOGY

EP400 Deposits H3.3 into Promoters and Enhancers during Gene Activation

(2016) Suman K. Pradhan et al.   MOLECULAR CELL

Histone variants on the move: substrates for chromatin dynamics

(2016) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The SNF2 family ATPase LSH promotes cell-autonomousde novoDNA methylation in somatic cells

(2016) Ausma Termanis et al.   NUCLEIC ACIDS RESEARCH

The First Rule of Plant Transposable Element Silencing: Location, Location, Location

(2016) Meredith J. Sigman et al.   PLANT CELL

The LSH/DDM1 Homolog MUS-30 Is Required for Genome Stability, but Not for DNA Methylation in Neurospora crassa

(2016) Evelina Y. Basenko et al.   PLoS Genetics

The H1 linker histones: multifunctional proteins beyond the nucleosomal core particle

(2015) S. P. Hergeth et al.   EMBO REPORTS

An ATPase-Deficient Variant of the SNF2 Family Member HELLS Shows Altered Dynamics at Pericentromeric Heterochromatin

(2015) Cristiana Lungu et al.   JOURNAL OF MOLECULAR BIOLOGY

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The ATP binding site of the chromatin remodeling homolog Lsh is required for nucleosome density and de novo DNA methylation at repeat sequences

(2015) Jianke Ren et al.   NUCLEIC ACIDS RESEARCH

Epigenetic Basis of Morphological Variation and Phenotypic Plasticity inArabidopsis thaliana

(2015) Rik Kooke et al.   PLANT CELL

Diversification of histone H2A variants during plant evolution

(2015) Tomokazu Kawashima et al.   TRENDS IN PLANT SCIENCE

Mutations in CDCA7 and HELLS cause immunodeficiency–centromeric instability–facial anomalies syndrome

(2015) Peter E. Thijssen et al.   Nature Communications

Genome-Wide Negative Feedback Drives Transgenerational DNA Methylation Dynamics in Arabidopsis

(2015) Tasuku Ito et al.   PLoS Genetics

Histone Chaperones: Assisting Histone Traffic and Nucleosome Dynamics

(2014) Zachary A. Gurard-Levin et al.   Annual Review of Biochemistry

Chromatin dynamics: Interplay between remodeling enzymes and histone modifications

(2014) Sarah G. Swygert et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The Histone Variant H2A.W Defines Heterochromatin and Promotes Chromatin Condensation in Arabidopsis

(2014) Ramesh Yelagandula et al.   CELL

Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways

(2014) Weishi Yu et al.   GENOME RESEARCH

Mice without MacroH2A Histone Variants

(2014) J. R. Pehrson et al.   MOLECULAR AND CELLULAR BIOLOGY

Genetic Perturbation of the Maize Methylome

(2014) Qing Li et al.   PLANT CELL

CG hypomethylation in Lsh-/- mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticity

(2014) W. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Arabidopsis Nucleosome Remodeler DDM1 Allows DNA Methyltransferases to Access H1-Containing Heterochromatin

(2013) Assaf Zemach et al.   CELL

Comprehensive Analysis of Silencing Mutants Reveals Complex Regulation of the Arabidopsis Methylome

(2013) Hume Stroud et al.   CELL

Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis

(2013) Hume Stroud et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DDM1 and ROS1 have a role in UV-B induced- and oxidative DNA damage in A. thaliana

(2013) Julia I. Qüesta et al.   Frontiers in Plant Science

Lsh regulates LTR retrotransposon repression independently of Dnmt3b function

(2013) Donncha S Dunican et al.   GENOME BIOLOGY

ATRX-mediated chromatin association of histone variant macroH2A1 regulates  -globin expression

(2012) K. Ratnakumar et al.   GENES & DEVELOPMENT

DDM1 (Decrease in DNA Methylation) genes in rice (Oryza sativa)

(2012) Hiromi Higo et al.   MOLECULAR GENETICS AND GENOMICS

Histone H2A variants in nucleosomes and chromatin: more or less stable?

(2012) C. Bonisch et al.   NUCLEIC ACIDS RESEARCH

A unified phylogeny-based nomenclature for histone variants

(2012) Paul B Talbert et al.   Epigenetics & Chromatin

Deposition of Histone Variant H2A.Z within Gene Bodies Regulates Responsive Genes

(2012) Devin Coleman-Derr et al.   PLoS Genetics

Lymphoid-Specific Helicase (HELLS) Is Essential for Meiotic Progression in Mouse Spermatocytes1

(2011) Wenxian Zeng et al.   BIOLOGY OF REPRODUCTION

The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays

(2011) Uma M. Muthurajan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS

(2011) Yongguang Tao et al.   NUCLEIC ACIDS RESEARCH

Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences

(2011) Y. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repetitive Elements May Comprise Over Two-Thirds of the Human Genome

(2011) A. P. Jason de Koning et al.   PLoS Genetics

Stepwise Histone Replacement by SWR1 Requires Dual Activation with Histone H2A.Z and Canonical Nucleosome

(2010) Ed Luk et al.   CELL

DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development

(2010) Tao Fan et al.   Epigenetics

LSH and G9a/GLP complex are required for developmentally programmed DNA methylation

(2010) K. Myant et al.   GENOME RESEARCH

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

(2010) Julie A. Law et al.   NATURE REVIEWS GENETICS

Gene Duplication and Hypermutation of the Pathogen Resistance Gene SNC1 in the Arabidopsis bal Variant

(2009) Hankuil Yi et al.   GENETICS

DNA methylation in early development

(2009) Theresa M. Geiman et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Bursts of retrotransposition reproduced in Arabidopsis

(2009) Sayuri Tsukahara et al.   NATURE

A Role for RNAi in the Selective Correction of DNA Methylation Defects

(2009) F. K. Teixeira et al.   SCIENCE

Lsh Participates in DNA Methylation and Silencing of Stem Cell Genes

(2009) Sichuan Xi et al.   STEM CELLS

macroH2A1-Dependent Silencing of Endogenous Murine Leukemia Viruses

(2008) L. N. Changolkar et al.   MOLECULAR AND CELLULAR BIOLOGY

Snf2 proteins in plants: gene silencing and beyond

(2008) Lukasz Knizewski et al.   TRENDS IN PLANT SCIENCE