KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19

Integrating T cell receptor sequences and transcriptional profiles by clonotype neighbor graph analysis (CoNGA)

(2021) Stefan A. Schattgen et al.   NATURE BIOTECHNOLOGY

Nanoparticle-enabled innate immune stimulation activates endogenous tumor-infiltrating T cells with broad antigen specificities

(2021) Qian Yin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease

(2020) Valérie Abadie et al.   NATURE

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Analyzing the Mycobacterium tuberculosis immune response by T-cell receptor clustering with GLIPH2 and genome-wide antigen screening

(2020) Huang Huang et al.   NATURE BIOTECHNOLOGY

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling

(2020) Lourdes Gimeno et al.   Cancers

Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

(2020) Yapeng Su et al.   CELL

Human Immunology through the Lens of Evolutionary Genetics

(2019) Lluis Quintana-Murci   CELL

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

(2019) Fan Zhang et al.   NATURE IMMUNOLOGY

Select sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansion

(2019) Huang Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

The immune cell landscape in kidneys of patients with lupus nephritis

(2019) Arnon Arazi et al.   NATURE IMMUNOLOGY

Distinct PLZF+CD8αα+ Unconventional T Cells Enriched in Liver Use a Cytotoxic Mechanism to Limit Autoimmunity

(2019) Huiming Sheng et al.   JOURNAL OF IMMUNOLOGY

Opposing T cell responses in experimental autoimmune encephalomyelitis

(2019) Naresha Saligrama et al.   NATURE

Rebooting Human Immunology

(2018) Mark M. Davis et al.   Annual Review of Immunology

Providence of CD25+ KIR+ CD127- FOXP3- CD8+ T cell subset determines the dynamics of tumor immune surveillance

(2018) Sreeparna Chakraborty et al.   IMMUNOLOGY AND CELL BIOLOGY

CD4+Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses

(2018) Meredith C. Rogers et al.   JOURNAL OF IMMUNOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR

(2018) David Zemmour et al.   NATURE IMMUNOLOGY

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

CD28− and CD28lowCD8+ Regulatory T Cells: Of Mice and Men

(2017) Yirajen Vuddamalay et al.   Frontiers in Immunology

CD8+CD122+CD49dlowregulatory T cells maintain T-cell homeostasis by killing activated T cells via Fas/FasL-mediated cytotoxicity

(2016) Kazuyuki Akane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of HIV Replication by CD8+ Regulatory T-Cells in Elite Controllers

(2016) Wei Lu et al.   Frontiers in Immunology

Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes

(2015) Wong Yu et al.   IMMUNITY

Ly49 receptors: evolution, genetic diversity, and impact on immunity

(2015) Mir Munir A. Rahim et al.   IMMUNOLOGICAL REVIEWS

Stable inhibitory activity of regulatory T cells requires the transcription factor Helios

(2015) H.-J. Kim et al.   SCIENCE

Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology

(2014) Jonas F Ludvigsson et al.   GUT

Linking T-cell receptor sequence to functional phenotype at the single-cell level

(2014) Arnold Han et al.   NATURE BIOTECHNOLOGY

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Virus-Specific CD4+ Memory-Phenotype T Cells Are Abundant in Unexposed Adults

(2013) Laura F. Su et al.   IMMUNITY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells

(2012) N. K. Bjorkstrom et al.   BLOOD

Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules

(2012) Ludvig M. Sollid et al.   IMMUNOGENETICS

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

(2011) Chris H. Polman et al.   ANNALS OF NEUROLOGY

Integration of Genetic and Immunological Insights into a Model of Celiac Disease Pathogenesis

(2011) Valérie Abadie et al.   Annual Review of Immunology

Partial Depletion of Natural CD4+CD25+ Regulatory T Cells with Anti-CD25 Antibody Does Not Alter the Course of Acute Influenza A Virus Infection

(2011) Richard J. Betts et al.   PLoS One

CD8+T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice

(2011) Hye-Jung Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of follicular T-helper cells by CD8+ regulatory T cells is essential for self tolerance

(2010) Hye-Jung Kim et al.   NATURE

Ligand-Independent Exhaustion of Killer Immunoglobulin-Like Receptor-Positive CD8+ T Cells in Human Immunodeficiency Virus Type 1 Infection

(2008) G. Alter et al.   JOURNAL OF VIROLOGY