Integration of Genetic and Immunological Insights into a Model of Celiac Disease Pathogenesis

Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection

(2010) Alexandra Zhernakova et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The prevalence of celiac disease in Europe: Results of a centralized, international mass screening project

(2010) Kirsi Mustalahti et al.   ANNALS OF MEDICINE

Increased IFN-α-induced sensitivity but reduced reactivity of 2′,5′-oligoadenylate synthetase (2,5AS) in trisomy 21 blood lymphocytes

(2010) A.-M. GERDES et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Coeliac disease: emerging in China?

(2010) J. Wu et al.   GUT

Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility

(2010) Rebecca L. Zuvich et al.   HUMAN GENETICS

CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis

(2010) Paola G. Bronson et al.   HUMAN MOLECULAR GENETICS

The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity

(2010) Kenji Yoshida et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease–associated inflammation and lymphomagenesis

(2010) Georgia Malamut et al.   JOURNAL OF CLINICAL INVESTIGATION

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

(2010) Dermot P B McGovern et al.   NATURE GENETICS

Chromogranin A is an autoantigen in type 1 diabetes

(2010) Brian D Stadinski et al.   NATURE IMMUNOLOGY

Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease

(2010) J. A. Tye-Din et al.   Science Translational Medicine

Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus

(2010) Wanling Yang et al.   PLoS Genetics

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Prevalence of celiac disease in inflammatory bowel diseases: An IG-IBD multicentre study

(2009) Giovanni Casella et al.   DIGESTIVE AND LIVER DISEASE

Follow-up of 1715 SNPs from the Wellcome Trust Case Control Consortium genome-wide association study in type I diabetes families

(2009) J D Cooper et al.   GENES AND IMMUNITY

Common and different genetic background for rheumatoid arthritis and coeliac disease

(2009) Marieke J.H. Coenen et al.   HUMAN MOLECULAR GENETICS

Cytosolic PLA2is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15

(2009) Fangming Tang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-15 Renders Conventional Lymphocytes Resistant to Suppressive Functions of Regulatory T Cells through Activation of the Phosphatidylinositol 3-Kinase Pathway

(2009) M. B. Ahmed et al.   JOURNAL OF IMMUNOLOGY

Screening Detects a High Proportion of Celiac Disease in Young HLA-genotyped Children

(2009) Sara Björck et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

(2009) Soumya Raychaudhuri et al.   NATURE GENETICS

REL, encoding a member of the NF-κB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis

(2009) Peter K Gregersen et al.   NATURE GENETICS

Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

(2009) Mark S Silverberg et al.   NATURE GENETICS

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

(2009) Melanie Bahlo et al.   NATURE GENETICS

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

(2009) Philip L De Jager et al.   NATURE GENETICS

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

(2009) Jian-Wen Han et al.   NATURE GENETICS

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

(2009) Rajan P Nair et al.   NATURE GENETICS

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation

(2009) Lars-Egil Fallang et al.   NATURE IMMUNOLOGY

From evolutionary genetics to human immunology: how selection shapes host defence genes

(2009) Luis B. Barreiro et al.   NATURE REVIEWS GENETICS

Genetic Analysis of Innate Immunity in Crohn's Disease and Ulcerative Colitis Identifies Two Susceptibility Loci Harboring CARD9 and IL18RAP

(2008) Alexandra Zhernakova et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Lower economic status and inferior hygienic environment may protect against celiac disease

(2008) Anita Kondrashova et al.   ANNALS OF MEDICINE

Immunity to Citrullinated Proteins in Rheumatoid Arthritis

(2008) Lars Klareskog et al.   Annual Review of Immunology

Recent Advances in the Genetics of Autoimmune Disease

(2008) Peter K. Gregersen et al.   Annual Review of Immunology

Genome-wide association study of rheumatoid arthritis in the Spanish population:KLF12as a risk locus for rheumatoid arthritis susceptibility

(2008) Antonio Julià et al.   ARTHRITIS AND RHEUMATISM

Follow-Up Analysis of Genome-Wide Association Data Identifies Novel Loci for Type 1 Diabetes

(2008) S. F.A. Grant et al.   DIABETES

A History of Coeliac Disease

(2008) M.S. Losowsky   DIGESTIVE DISEASES

Association study of the IL18RAP locus in three European populations with coeliac disease

(2008) Lotta L.E. Koskinen et al.   HUMAN MOLECULAR GENETICS

The role of HLA-DQ8 β57 polymorphism in the anti-gluten T-cell response in coeliac disease

(2008) Zaruhi Hovhannisyan et al.   NATURE

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

(2008) Jason D Cooper et al.   NATURE GENETICS

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

(2008) Soumya Raychaudhuri et al.   NATURE GENETICS

Newly identified genetic risk variants for celiac disease related to the immune response

(2008) Karen A Hunt et al.   NATURE GENETICS

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

(2008) Robert R Graham et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

(2008) Deborah J. Smyth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of Systemic Lupus Erythematosus withC8orf13–BLKandITGAM–ITGAX

(2008) Geoffrey Hom et al.   NEW ENGLAND JOURNAL OF MEDICINE

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH

Extracellular Transglutaminase 2 Is Catalytically Inactive, but Is Transiently Activated upon Tissue Injury

(2008) Matthew Siegel et al.   PLoS One

Identification of a Novel Risk Locus for Multiple Sclerosis at 13q31.3 by a Pooled Genome-Wide Scan of 500,000 Single Nucleotide Polymorphisms

(2008) Manuel Comabella et al.   PLoS One