Antiinflammatory activity of natural triterpenes—An overview from 2006 to 2021

Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L . (garden angelica) and its bioactive components

(2021) Anudeep Kaur et al.   PHYTOTHERAPY RESEARCH

Araloside C attenuates atherosclerosis by modulating macrophage polarization via Sirt1-mediated autophagy

(2020) Yun Luo et al.   Aging-US

Serratane triterpenoids isolated from Lycopodium clavatum by bioactivity-guided fractionation attenuate the production of inflammatory mediators

(2020) Ara Jo et al.   BIOORGANIC CHEMISTRY

Chemosensitisation of Therapy Resistant Tumors: Targeting Multiple cell Signaling pathways by Lupeol, A Pentacyclic Triterpene

(2020) Santosh K Maurya et al.   CURRENT PHARMACEUTICAL DESIGN

Celastrol: Progresses in structure-modifications, structure-activity relationships, pharmacology and toxicology

(2020) Wei Hou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Astragaloside IV attenuates IL-1β secretion by enhancing autophagy in H1N1 infection

(2020) Jing Zhang et al.   FEMS MICROBIOLOGY LETTERS

Chondro-protective effects of celastrol on osteoarthritis through autophagy activation and NF-κB signaling pathway inhibition

(2020) Kai Feng et al.   INFLAMMATION RESEARCH

Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation

(2020) Jing Su et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

High-Mobility Group Box 1 Protein Signaling in Painful Diabetic Neuropathy

(2020) Vikram Thakur et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

3,4-seco-Dammarane Triterpenoid Saponins with Anti-Inflammatory Activity Isolated from the Leaves of Cyclocarya paliurus

(2020) Wei Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Biological Activities of Gedunin—A Limonoid from the Meliaceae Family

(2020) Teresa M. Braga et al.   MOLECULES

Rat Chondrocyte Inflammation and Osteoarthritis Are Ameliorated by Madecassoside

(2020) Safwat Adel Abdo Moqbel et al.   Oxidative Medicine and Cellular Longevity

Astragaloside IV protects ATDC5 cells from lipopolysaccharide-caused damage through regulating miR-203/MyD88

(2020) Dexin Li et al.   PHARMACEUTICAL BIOLOGY

Ginsenoside Rg1 and the control of inflammation implications for the therapy of type 2 diabetes: A review of scientific findings and call for further research

(2020) Raphael N. Alolga et al.   PHARMACOLOGICAL RESEARCH

Notoginsenoside R1 Suppresses Inflammatory Signaling and Rescue Renal Ischemia-reperfusion Injury in Experimental Rats

(2020) Chuming Fan et al.   MEDICAL SCIENCE MONITOR

Rg1 improves LPS-induced Parkinsonian symptoms in mice via inhibition of NF-κB signaling and modulation of M1/M2 polarization

(2020) Jia-qi Liu et al.   ACTA PHARMACOLOGICA SINICA

Celastrol ameliorates acute liver injury through modulation of PPARα

(2020) Qi Zhao et al.   BIOCHEMICAL PHARMACOLOGY

18α-Glycyrrhetinic acid (GA) ameliorates fructose-induced nephropathy in mice by suppressing oxidative stress, dyslipidemia and inflammation

(2020) Xiaoli Cheng et al.   BIOMEDICINE & PHARMACOTHERAPY

Serratane triterpenoids from Lycopodium complanatum and their anti-cancer and anti-inflammatory activities

(2020) Wenhao Zhou et al.   BIOORGANIC CHEMISTRY

Tripterine is a potential anti-allergic compound

(2020) Bao-jun Zhu et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Three new triterpenoids from Mallotus macrostachyus

(2020) Hui-Min Gao et al.   FITOTERAPIA

Anti-neuroinflammatory triterpenoids from the seeds of Quercus serrata Thunb

(2020) Yongxin Mai et al.   FITOTERAPIA

Anti-allergic effect of inotodiol, a lanostane triterpenoid from Chaga mushroom, via selective inhibition of mast cell function

(2020) Thi Minh Nguyet Nguyen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice

(2020) Puze Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19

(2020) Pan Luo et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in Panax Genus, against Acetic Acid-Induced Gastric Ulcer in Rats Based on Untargeted Metabolomics

(2020) Cuizhu Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ginsenoside Rg3 Alleviates Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Mice by Regulating CD4+CD25+Foxp3+Treg Cells

(2020) Yan Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Severe Acute Lung Injury Related to COVID‐19 Infection: A Review and the Possible Role for Escin

(2020) Luca Gallelli et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Ginsenoside metabolite 20(S)-protopanaxatriol from Panax ginseng attenuates inflammation-mediated NLRP3 inflammasome activation

(2020) Jun Jiang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cucurbitane-Type Triterpenoids from the Vines of Momordica charantia and Their Anti-inflammatory Activities

(2020) Hung-Tse Huang et al.   JOURNAL OF NATURAL PRODUCTS

Astragaloside IV inhibits astrocyte senescence: implication in Parkinson’s disease

(2020) Mei-Ling Xia et al.   Journal of Neuroinflammation

Neuroprotective effect of tormentic acid against memory impairment and neuro‑inflammation in an Alzheimer's disease mouse model

(2020) Weigang Cui et al.   Molecular Medicine Reports

Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products

(2020) Nathaniel C. Gilbert et al.   Nature Chemical Biology

Lanostane triterpenoids with anti-inflammatory activities from Ganoderma lucidum

(2020) Hai-Guo Su et al.   PHYTOCHEMISTRY

Ginsenoside Rb1 exerts anti-inflammatory effects in vitro and in vivo by modulating toll-like receptor 4 dimerization and NF-kB/MAPKs signaling pathways

(2020) Hongwei Gao et al.   PHYTOMEDICINE

A dual effect of ursolic acid to the treatment of multiple sclerosis through both immunomodulation and direct remyelination

(2020) Yuan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herbal Combinational Medication of Glycyrrhiza glabra, Agastache rugosa Containing Glycyrrhizic Acid, Tilianin Inhibits Neutrophilic Lung Inflammation by Affecting CXCL2, Interleukin-17/STAT3 Signal Pathways in a Murine Model of COPD

(2020) Seung-Hyung Kim et al.   Nutrients

A Novel Combination of Vitamin C, Curcumin and Glycyrrhizic Acid Potentially Regulates Immune and Inflammatory Response Associated with Coronavirus Infections: A Perspective from System Biology Analysis

(2020) Liang Chen et al.   Nutrients

Synthesis of 2-(2-Hydroxyethoxy)-3-hydroxysqualene and Characterization of Its Anti-Inflammatory Effects

(2020) Kazunori Sasaki et al.   Biomed Research International

Symptomatic Protective Action of Glycyrrhizin (Licorice) in COVID-19 Infection?

(2020) Harald Murck   Frontiers in Immunology

Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing the neuroinflammatory response

(2020) Zhiman Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hopane-type triterpenes from Cnidoscolus spinosus and their bioactivities

(2020) Fabiola A. López-Huerta et al.   BIOORGANIC CHEMISTRY

Euphane- and 19(10 → 9)abeo-euphane-type triterpenoids from Jatropha gossypiifolia

(2020) Si-Yuan Luo et al.   FITOTERAPIA

Boswellia carteri extract and 3-O-acetyl-alpha-boswellic acid suppress T cell function

(2020) Amy M. Zimmermann-Klemd et al.   FITOTERAPIA

Hederacoside-C protects against AGEs-induced ECM degradation in mice chondrocytes

(2020) Hai-chao Xu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ginsenoside Rg3 ameliorates acute exacerbation of COPD by suppressing neutrophil migration

(2020) Xuewa Guan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Glycyrrhetinic acid alleviates hepatic inflammation injury in viral hepatitis disease via a HMGB1-TLR4 signaling pathway

(2020) Xiaodong Shi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

From Inflammation to Cutaneous Repair: Topical Application of Lupeol Improves Skin Wound Healing in Rats by Modulating the Cytokine Levels, NF-κB, Ki-67, Growth Factor Expression, and Distribution of Collagen Fibers

(2020) Fernando Pereira Beserra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aphananoid A is an Anti-Inflammatory Limonoid with a New 5/6/5 Fused Ring Featuring a C24 Carbon Skeleton from Aphanamixis polystachya

(2020) Bi-Juan Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

Escin alleviates peripheral neuropathy in streptozotocin induced diabetes in rats

(2020) Sachin V. Suryavanshi et al.   LIFE SCIENCES

Acyclic Triterpenoid Isolated from Alpinia katsumadai Alleviates Formalin-Induced Chronic Mouse Paw Inflammation by Inhibiting the Phosphorylation of ERK and NF-κB

(2020) Hyung Jin Lim et al.   MOLECULES

Chemosystematically valuable triterpenoid saponins from Glandularia x hybrida

(2020) Nesma M. Mohamed et al.   PHYTOCHEMISTRY

Ternstroenols A – E: Undescribed pentacyclic triterpenoids from the Australian rainforest plant Ternstroemia cherryi

(2020) Ahilya Singh et al.   PHYTOCHEMISTRY

Potential mechanisms of action of celastrol against rheumatoid arthritis: Transcriptomic and proteomic analysis

(2020) Song Xinqiang et al.   PLoS One

Celastrol augments sensitivity of NLRP3 to CP-456773 by modulating HSP-90 and inducing autophagy in dextran sodium sulphate-induced colitis in rats

(2020) Sameh Saber et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Intra-articular delivery of celastrol by hollow mesoporous silica nanoparticles for pH-sensitive anti-inflammatory therapy against knee osteoarthritis

(2020) Tian Jin et al.   JOURNAL OF NANOBIOTECHNOLOGY

Root Extracts From Ononis spinosa Inhibit IL-8 Release via Interactions With Toll-Like Receptor 4 and Lipopolysaccharide

(2020) Verena Spiegler et al.   Frontiers in Pharmacology

Astragaloside IV ameliorates preeclampsia-induced oxidative stress through Nrf2/HO-1 pathway in a rat model

(2020) Shuangyan Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ursolic acid protects chondrocytes, exhibits anti-inflammatory properties via regulation of the NF-κB/NLRP3 inflammasome pathway and ameliorates osteoarthritis

(2020) Chunli Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Angiogenic and anti-inflammatory properties of azadirachtin A improve random skin flap survival in rats

(2020) Ji-Bing He et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Anti-inflammatory norhopanes from the root bark of Fagaropsis angolensis (Engl.) H.M.Gardner

(2020) Justus Mukavi et al.   FITOTERAPIA

Sudachinoid- and Ichangensin-Type Limonoids from Citrus junos Downregulate Pro-Inflammatory Cytokines

(2020) Jihun Shin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lanostane Triterpenoids with PTP1B Inhibitory and Glucose-Uptake Stimulatory Activities from Mushroom Fomitopsis pinicola Collected in North America

(2020) Jinjin Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Celastrol Dilates and Counteracts Ethanol-Induced Constriction of Cerebral Arteries

(2020) Kelsey North et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Structure elucidation of a new triterpene from Inonotus obliquus

(2020) Sangmin Park et al.   MAGNETIC RESONANCE IN CHEMISTRY

Enhancement of an In Vivo Anti-Inflammatory Activity of Oleanolic Acid through Glycosylation Occurring Naturally in Stauntonia hexaphylla

(2020) Le Ba Vinh et al.   MOLECULES

Lupeol Counteracts the Proinflammatory Signalling Triggered in Macrophages by 7-Keto-Cholesterol: New Perspectives in the Therapy of Atherosclerosis

(2020) Sarmistha Saha et al.   Oxidative Medicine and Cellular Longevity

Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?

(2020) Christian Bailly et al.   PHARMACOLOGY & THERAPEUTICS

Lanostane-type triterpenoids from Ganoderma applanatum and their inhibitory activities on NO production in LPS-induced BV-2 cells

(2020) Di Luo et al.   PHYTOCHEMISTRY

Oleanolic acid protects against mast cell-mediated allergic responses by suppressing Akt/ NF-κB and STAT1 activation

(2020) Yun-Mi Kang et al.   PHYTOMEDICINE

Celastrol ameliorates P. acnes/LPS-induced liver damage and MSU-induced gouty arthritis via inhibiting K63 deubiquitination of NLRP3

(2020) Chang-Yu Yan et al.   PHYTOMEDICINE

Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review

(2020) Boju Sun et al.   Frontiers in Pharmacology

Diterpenoids and triterpenoids from Triadica rotundifolia and their effects on microglial nitric oxide production

(2020) Hai-Yan Zhao et al.   BIOORGANIC CHEMISTRY

Anti-inflammatory and anti-gouty-arthritic effect of free Ginsenoside Rb1 and nano Ginsenoside Rb1 against MSU induced gouty arthritis in experimental animals

(2020) Yuan Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Optimization of antioxidant, anti-diabetic, and anti-inflammatory activities and ganoderic acid content of differentially dried Ganoderma lucidum using response surface methodology

(2020) Da Hye Ryu et al.   FOOD CHEMISTRY

Ursolic acid ameliorates hypobaric hypoxia‐induced skeletal muscle protein loss via upregulating Akt pathway: An experimental study using rat model

(2020) Richa Rathor et al.   IUBMB LIFE

Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives

(2020) Xianjing Zhang et al.   JOURNAL OF NATURAL PRODUCTS

Oleanolic acid ameliorates intestinal alterations associated with EAE

(2020) Beatriz Gutierrez et al.   Journal of Neuroinflammation

Chemical profile of Cimicifuga heracleifolia Kom. And immunomodulatory effect of its representative bioavailable component, cimigenoside on Poly(I:C)-induced airway inflammation

(2020) Liufang Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Nimbolide exerts protective effects in complete Freund's adjuvant induced inflammatory arthritis via abrogation of STAT-3/NF-κB/Notch-1 signaling

(2020) Pratibha Anchi et al.   LIFE SCIENCES

Tirucallane triterpenoids from the mastic (Pistacia lentiscus) and their anti-inflammatory and cytotoxic activities

(2020) Wei Liu et al.   PHYTOCHEMISTRY

Saikosaponin a attenuates lead-induced kidney injury through activating Nrf2 signaling pathway

(2020) Yanyan Song et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

New nor-oleanane triterpenoids from the fruits of Stauntonia brachyanthera with potential anti-inflammation activity

(2019) Jiaheng Li et al.   NATURAL PRODUCT RESEARCH

A new triterpenoid and a new flavonoid glycoside isolated from Bupleurum marginatum and their anti-inflammatory activity

(2019) Zhiqiang Lei et al.   NATURAL PRODUCT RESEARCH

Evaluation of Anti-Inflammatory Activities of a Triterpene β-Elemonic Acid in Frankincense In Vivo and In Vitro

(2019) Yue Zhang et al.   MOLECULES

Lupenone is a good anti-inflammatory compound based on the network pharmacology

(2019) Feng Xu et al.   MOLECULAR DIVERSITY

Anti-inflammatory and antihistaminic activity of triterpenoids isolated from Bursera cuneata (Schldl.) Engl

(2019) Verónica Rodríguez-López et al.   JOURNAL OF ETHNOPHARMACOLOGY

Bioactive triterpenoids from Sambucus javanica Blume

(2019) Feilong Chen et al.   NATURAL PRODUCT RESEARCH

23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9

(2019) Hui-hui Li et al.   ACTA PHARMACOLOGICA SINICA

Chemical constituents from Vietnamese mangrove Calophyllum inophyllum and their anti-inflammatory effects

(2019) Nguyen Van Thanh et al.   BIOORGANIC CHEMISTRY

Cucurbitane-type compounds from Momordica charantia: Isolation, in vitro antidiabetic, anti-inflammatory activities and in silico modeling approaches

(2019) Siddanagouda R. Shivanagoudra et al.   BIOORGANIC CHEMISTRY

Anti-inflammatory terpenes from Schefflera rubriflora C. J. Tseng & G. Hoo with their TNF-α and IL-6 inhibitory activities

(2019) Fenghua Li et al.   PHYTOCHEMISTRY

Polygalasaponin F treats mice with pneumonia induced by influenza virus

(2019) Yi Ye et al.   INFLAMMOPHARMACOLOGY

Anti-inflammatory and cytotoxic activities of the extracts, fractions, and chemical constituents isolated from Luehea ochrophylla Mart

(2019) Clináscia Rodrigues Rocha Araújo et al.   BMC Complementary and Alternative Medicine

Ginsenoside Rg3 suppresses the NLRP3 inflammasome activation through inhibition of its assembly

(2019) Yuhua Shi et al.   FASEB JOURNAL

Three new triterpenoids with their bioactives from the roots of Rosa cymosa

(2019) Yubin Ji et al.   NATURAL PRODUCT RESEARCH

Combination of tanshinone IIA and astragaloside IV attenuate atherosclerotic plaque vulnerability in ApoE(-/-) mice by activating PI3K/AKT signaling and suppressing TRL4/NF-κB signaling

(2019) Nanding Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Saikosaponin A ameliorates nasal inflammation by suppressing IL-6/ROR-γt/STAT3/IL-17/NF-κB pathway in OVA-induced allergic rhinitis

(2019) Chun Hua Piao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Protective effect of triterpenes of Ganoderma lucidum on lipopolysaccharide-induced inflammatory responses and acute liver injury

(2019) Zhongpeng Hu et al.   CYTOKINE

Hederacoside-C Inhibition of Staphylococcus aureus-Induced Mastitis via TLR2 & TLR4 and Their Downstream Signaling NF-κB and MAPKs Pathways In Vivo and In Vitro

(2019) Muhammad Akhtar et al.   INFLAMMATION

Asiaticoside nitric oxide gel accelerates diabetic cutaneous ulcers healing by activating Wnt/β-catenin signaling pathway

(2019) Xuqiang Nie et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A Review of the Pharmacological Efficacy and Safety of Licorice Root from Corroborative Clinical Trial Findings

(2019) Yu-Jin Kwon et al.   JOURNAL OF MEDICINAL FOOD

Saikosaponin B2 attenuates kidney fibrosis via inhibiting the Hedgehog Pathway

(2019) Dadui Ren et al.   PHYTOMEDICINE

Celastrol is a novel selective agonist of cannabinoid receptor 2 with anti-inflammatory and anti-fibrotic activity in a mouse model of systemic sclerosis

(2019) Xingwu Jiang et al.   PHYTOMEDICINE

Pristimerin suppresses colorectal cancer through inhibiting inflammatory responses and Wnt/β-catenin signaling

(2019) Qun Zhao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Ursane-type triterpenoids from the roots of Rosa multiflora with their anti-inflammatory activity

(2018) Hai Jiang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Anti-inflammatory activity of saponins from roots of Impatiens parviflora DC.

(2018) Karolina Grabowska et al.   NATURAL PRODUCT RESEARCH

Anti-inflammatory pentacyclic triterpenes from the stems of Euonymus carnosus

(2017) Jian Zhou et al.   FITOTERAPIA

Anti-proliferative and anti-inflammatory effects of 3β,6β,16β-Trihydroxylup-20(29)-ene on cutaneous inflammation

(2017) Cintia Delai da Silva Horinouchi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Inflammation in gout: mechanisms and therapeutic targets

(2017) Alexander K. So et al.   Nature Reviews Rheumatology

Anti-inflammatory, antimicrobial and acetylcholinesterase inhibitory activities of friedelanes from Maytenus robusta branches and isolation of further triterpenoids

(2017) Grasiely F. de Sousa et al.   Phytochemistry Letters

Cytotoxic, anti-HIV–1 and anti-inflammatory activities of lanostanes from fruits of Garcinia speciosa

(2017) Phanruethai Pailee et al.   Phytochemistry Letters

Anti-inflammatory and antioxidative effects of six pentacyclic triterpenes isolated from the Mexican copal resin of Bursera copallifera

(2016) Antonio Romero-Estrada et al.   BMC Complementary and Alternative Medicine

Terpenoids with anti-inflammatory activity from Abies chensiensis

(2016) Qian-Qian Zhao et al.   FITOTERAPIA

Anti-inflammatory triterpenes from the apical bud of Gardenia sootepensis

(2016) Ui Joung Youn et al.   FITOTERAPIA

Anti-Inflammatory Activity of Natural Products

(2016) Abdullatif Azab et al.   MOLECULES

Wild Bitter Melon Leaf Extract Inhibits Porphyromonas gingivalis-Induced Inflammation: Identification of Active Compounds through Bioassay-Guided Isolation

(2016) Tzung-Hsun Tsai et al.   MOLECULES

A Critical Approach to Evaluating Clinical Efficacy, Adverse Events and Drug Interactions of Herbal Remedies

(2016) Angelo A. Izzo et al.   PHYTOTHERAPY RESEARCH

Anti-Inflammatory Activity of Triterpenes Isolated fromProtium paniculatumOil-Resins

(2015) Patrícia D. O. de Almeida et al.   Evidence-based Complementary and Alternative Medicine

Negative regulation of the inflammasome: keeping inflammation under control

(2015) Gustavo Pedraza-Alva et al.   IMMUNOLOGICAL REVIEWS

Interleukin-17 and innate immunity in infections and chronic inflammation

(2015) Natasa Isailovic et al.   JOURNAL OF AUTOIMMUNITY

The biology of innate lymphoid cells

(2015) David Artis et al.   NATURE

The antinociceptive effects of the tetracyclic triterpene euphol in inflammatory and neuropathic pain models: The potential role of PKCε

(2015) R.C. Dutra et al.   NEUROSCIENCE

Oleanane-type triterpenoid: an anti-inflammatory compound of the roots Arrabidaea brachypoda

(2015) Cláudia Q. da Rocha et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Anti-inflammatory effects of triterpenes and steroid compounds isolated from the stem bark of Hiptage benghalensis

(2015) Chin-Lin Hsu et al.   Journal of Functional Foods

Oleanane-type triterpenoid: an anti-inflammatory compound of the roots Arrabidaea brachypoda

(2015) Cláudia Q. da Rocha et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Synthesis, anti-inflammatory activity and modeling studies of cycloartane-type terpenes derivatives isolated from Parthenium argentatum

(2014) Juan Carlos Romero et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Potent anti-inflammatory activity of betulinic acid treatment in a model of lethal endotoxemia

(2014) José Fernando Oliveira Costa et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Anti-Inflammatory Effects of Triterpenoids; Naturally Occurring and Synthetic Agents

(2014) Gil-Saeng Jeong et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Targeting inflammation in the treatment of type 2 diabetes: time to start

(2014) Marc Y. Donath   NATURE REVIEWS DRUG DISCOVERY

Review on Liver Inflammation and Antiinflammatory Activity ofAndrographis paniculatafor Hepatoprotection

(2014) Lee Suan Chua   PHYTOTHERAPY RESEARCH

Anti-inflammatory and heme oxygenase-1 inducing activities of lanostane triterpenes isolated from mushroom Ganoderma lucidum in RAW264.7 cells

(2014) Solip Choi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

TNF-α signalling and inflammation: interactions between old acquaintances

(2013) Hana Zelová et al.   INFLAMMATION RESEARCH

Anti-inflammatory and anti-hypersensitive effects of the crude extract, fractions and triterpenes obtained from Chrysophyllum cainito leaves in mice

(2013) Nicole Anzanelo Meira et al.   JOURNAL OF ETHNOPHARMACOLOGY

Interleukin-1α

(2013) Peleg Rider et al.   SEMINARS IN IMMUNOLOGY

TNF-α Inhibitors with Anti-Oxidative Stress Activity from Natural Products

(2012) Jing Li et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice

(2012) Giselle F. Passos et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-inflammatory effect of triterpene 3β, 6β, 16β-trihydroxylup-20(29)-ene obtained from Combretum leprosum Mart & Eich in mice

(2012) Daniela T. Longhi-Balbinot et al.   JOURNAL OF ETHNOPHARMACOLOGY

IL-12 family cytokines: immunological playmakers

(2012) Dario A A Vignali et al.   NATURE IMMUNOLOGY

Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system

(2012) Rafael Cypriano Dutra et al.   NEUROPHARMACOLOGY

Diterpenoids and triterpenoids with potential anti-inflammatory activity from the leaves of Aglaia odorata

(2012) Orapun Yodsaoue et al.   PHYTOCHEMISTRY

Anti-inflammatory effects of maslinic acid, a natural triterpene, in cultured cortical astrocytes via suppression of nuclear factor-kappa B

(2011) Longfei Huang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-inflammatory Triterpenes from the Leaves ofRosa laevigata

(2011) Na Zeng et al.   JOURNAL OF NATURAL PRODUCTS

Tumor Necrosis Factor-alpha and the Roles it Plays in Homeostatic and Degenerative Processes Within the Central Nervous System

(2011) Sara L. Montgomery et al.   Journal of Neuroimmune Pharmacology

Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice

(2011) Kathryn A.B. Simão da Silva et al.   PAIN

Triterpene compounds isolated from Acer mandshuricum and their anti-inflammatory activity

(2010) Yan Ding et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

IL-10 family of cytokines

(2010) Robert Sabat   CYTOKINE & GROWTH FACTOR REVIEWS

Topical anti-inflammatory effect of tirucallol, a triterpene isolated from Euphorbia lactea latex

(2009) A. Fernandez-Arche et al.   PHYTOMEDICINE