Fusobacterium nucleatum and cancer

Diagnostic accuracy of Fusobacterium nucleatum IgA and IgG ELISA test in colorectal cancer

(2021) Melike Kurt et al.   Scientific Reports

Fecal Immunochemical Tests Detect Screening Participants with Multiple Advanced Adenomas Better than T1 Colorectal Cancers

(2021) Anton Gies et al.   Cancers

The onco-immunological implications of Fusobacterium nucleatum in breast cancer

(2021) Michelle Van der Merwe et al.   IMMUNOLOGY LETTERS

The microbiome and human cancer

(2021) Gregory D. Sepich-Poore et al.   SCIENCE

Bladder Cancer Immunotherapy by BCG Is Associated with a Significantly Reduced Risk of Alzheimer’s Disease and Parkinson’s Disease

(2021) Danielle Klinger et al.   Vaccines

Fusobacterium nucleatum CbpF Mediates Inhibition of T Cell Function Through CEACAM1 Activation

(2021) Johanna Galaski et al.   Frontiers in Cellular and Infection Microbiology

Colorectal cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Fusobacterium nucleatum in the Colorectum and Its Association with Cancer Risk and Survival: A Systematic Review and Meta-analysis

(2020) Christian Gethings-Behncke et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

From Beyond the Pale to the Pale Riders: The Emerging Association of Bacteria with Oral Cancer

(2020) Z.R. Fitzsimonds et al.   JOURNAL OF DENTAL RESEARCH

The landscape of viral associations in human cancers

(2020) Marc Zapatka et al.   NATURE GENETICS

Development of Oral Care Chip, a novel device for quantitative detection of the oral microbiota associated with periodontal disease

(2020) Ai Nozawa et al.   PLoS One

Fusobacterium nucleatum promotes colorectal cancer metastasis by modulating KRT7-AS/KRT7

(2020) Shujie Chen et al.   Gut Microbes

Microbiome analyses of blood and tissues suggest cancer diagnostic approach

(2020) Gregory D. Poore et al.   NATURE

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

(2020) Deborah Nejman et al.   SCIENCE

Fusobacterium nucleatum persistence and risk of recurrence after preoperative treatment in locally advanced rectal cancer

(2020) G. Serna et al.   ANNALS OF ONCOLOGY

Trained immunity as a molecular mechanism for BCG immunotherapy in bladder cancer

(2020) Jelmer H. van Puffelen et al.   Nature Reviews Urology

Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration

(2020) Michael A. Casasanta et al.   Science Signaling

Association of Bacillus Calmette–Guerin shortages with bladder cancer recurrence: A single-center retrospective study

(2020) Sangmin Lee et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

(2020) Lishay Parhi et al.   Nature Communications

Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System

(2020) Jawad Abed et al.   Frontiers in Cellular and Infection Microbiology

Involvement of Fusobacterium Species in Oral Cancer Progression: A Literature Review Including Other Types of Cancer

(2020) Natsumi Fujiwara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fusobacterium nucleatum confers chemoresistance by modulating autophagy in oesophageal squamous cell carcinoma

(2020) Yang Liu et al.   BRITISH JOURNAL OF CANCER

Cancer and the Microbiome—Influence of the Commensal Microbiota on Cancer, Immune Responses, and Immunotherapy

(2020) Vyara Matson et al.   GASTROENTEROLOGY

Bladder Cancer

(2020) Andrew T. Lenis et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Could Periodontal Disease through Periopathogen Fusobacterium nucleatum Be an Aggravating Factor for Gastric Cancer?

(2020) Petra Șurlin et al.   Journal of Clinical Medicine

Detection of Fusobaterium nucleatum in feces and colorectal mucosa as a risk factor for colorectal cancer: a systematic review and meta-analysis

(2020) Amal Idrissi Janati et al.   Systematic Reviews

The role of the gut microbiome on radiation therapy efficacy and gastrointestinal complications: A systematic review

(2020) Marion Tonneau et al.   RADIOTHERAPY AND ONCOLOGY

Proliferative Effect of FadA Recombinant Protein from Fusobacterium nucleatum on SW480 Colorectal Cancer Cell Line

(2020) Masoud Dadashi et al.   Infectious Disorders - Drug Targets

Fusobacterium nucleatum promotes chemoresistance to 5-fluorouracil by upregulation of BIRC3 expression in colorectal cancer

(2019) Sheng Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Fusobacterium nucleatum supresses anti-tumor immunity by activating CEACAM1

(2019) Chamutal Gur et al.   OncoImmunology

The Helicobacter pylori HopQ outermembrane protein inhibits immune cell activities

(2019) Chamutal Gur et al.   OncoImmunology

Fusobacterium spp. target human CEACAM1 via the trimeric autotransporter adhesin CbpF

(2019) Matthew L. Brewer et al.   Journal of Oral Microbiology

The microbiome, cancer, and cancer therapy

(2019) Beth A. Helmink et al.   NATURE MEDICINE

Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer

(2019) Rogier Aäron Gaiser et al.   GUT

Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β‐catenin modulator Annexin A1

(2019) Mara Roxana Rubinstein et al.   EMBO REPORTS

Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

(2019) Chengcheng Jin et al.   CELL

International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis

(2019) Alasdair J Scott et al.   GUT

The negative impact of antibiotics on outcomes in cancer patients treated with immunotherapy: a new independent prognostic factor?

(2019) A Elkrief et al.   ANNALS OF ONCOLOGY

Intratumoral Fusobacterium nucleatum levels predict therapeutic response to neoadjuvant chemotherapy in esophageal squamous cell carcinoma

(2019) Kensuke Yamamura et al.   CLINICAL CANCER RESEARCH

Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation

(2019) Triantafyllos Chavakis et al.   NATURE IMMUNOLOGY

Fusobacterium nucleatum Contributes to the Carcinogenesis of Colorectal Cancer by Inducing Inflammation and Suppressing Host Immunity

(2019) Jiao Wu et al.   Translational Oncology

Purified human anti-Tn and anti-T antibodies specifically recognize carcinoma tissues

(2019) Natacha Zlocowski et al.   Scientific Reports

Genomic, morphological and functional characterisation of novel bacteriophage FNU1 capable of disrupting Fusobacterium nucleatum biofilms

(2019) Mwila Kabwe et al.   Scientific Reports

Global Investigations of Fusobacterium nucleatum in Human Colorectal Cancer

(2019) Seul A. Lee et al.   Frontiers in Oncology

Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy

(2019) Di-Wei Zheng et al.   Nature Biomedical Engineering

Fusobacterium nucleatum, the communication with colorectal cancer

(2019) Kangjia Luo et al.   BIOMEDICINE & PHARMACOTHERAPY

Antibody Responses to Fusobacterium nucleatum Proteins in Prediagnostic Blood Samples are not Associated with Risk of Developing Colorectal Cancer

(2019) Julia Butt et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Fusobacterium nucleatum prevents apoptosis in colorectal cancer cells via the ANO1 pathway

(2019) Pei Lu et al.   Cancer Management and Research

Commensal Koch's postulates: establishing causation in human microbiota research

(2018) B Anne Neville et al.   CURRENT OPINION IN MICROBIOLOGY

Patients with colorectal cancer have identical strains ofFusobacterium nucleatumin their colorectal cancer and oral cavity

(2018) Yasuhiko Komiya et al.   GUT

TOX expression decreases with progression of colorectal cancers and is associated with CD4 T-cell density and Fusobacterium nucleatum infection

(2018) Ting Chen et al.   HUMAN PATHOLOGY

Mechanisms of BCG immunotherapy and its outlook for bladder cancer

(2018) Caroline Pettenati et al.   Nature Reviews Urology

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC

(2018) Chenggang Wu et al.   mBio

Increased Abundance of Clostridium and Fusobacterium in Gastric Microbiota of Patients with Gastric Cancer in Taiwan

(2018) Yung-Yu Hsieh et al.   Scientific Reports

Association between Fusobacterium nucleatum and colorectal cancer: Progress and future directions

(2018) Sheng Zhang et al.   Journal of Cancer

Fusobacterium nucleatum and colorectal cancer: A review

(2018) Fu-Mei Shang et al.   World Journal of Gastrointestinal Oncology

Progress in characterizing the linkage between Fusobacterium nucleatum and gastrointestinal cancer

(2018) Yang Liu et al.   JOURNAL OF GASTROENTEROLOGY

The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

(2018) Mette Ø. Agerbæk et al.   Nature Communications

Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status

(2018) Tsuyoshi Hamada et al.   Cancer Immunology Research

Fusobacterium nucleatum — symbiont, opportunist and oncobacterium

(2018) Caitlin A. Brennan et al.   NATURE REVIEWS MICROBIOLOGY

The oral microbiota: dynamic communities and host interactions

(2018) Richard J. Lamont et al.   NATURE REVIEWS MICROBIOLOGY

Fighting Cancer Using an Oncofetal Glycosaminoglycan-Binding Protein from Malaria Parasites

(2018) Mette Ø. Agerbæk et al.   TRENDS IN PARASITOLOGY

Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21

(2017) Yongzhi Yang et al.   GASTROENTEROLOGY

Fusobacterium nucleatum as a prognostic marker of colorectal cancer in a Japanese population

(2017) Yuko Yamaoka et al.   JOURNAL OF GASTROENTEROLOGY

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Analysis ofFusobacteriumpersistence and antibiotic response in colorectal cancer

(2017) Susan Bullman et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Tumor Targeting by Fusobacterium nucleatum: A Pilot Study and Future Perspectives

(2017) Jawad Abed et al.   Frontiers in Cellular and Infection Microbiology

Gut Microbiota, Inflammation, and Colorectal Cancer

(2016) Caitlin A. Brennan et al.   Annual Review of Microbiology

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc

(2016) Jawad Abed et al.   Cell Host & Microbe

Human Microbiome Fusobacterium Nucleatum in Esophageal Cancer Tissue Is Associated with Prognosis

(2016) Kensuke Yamamura et al.   CLINICAL CANCER RESEARCH

Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer

(2016) Qiaoyi Liang et al.   CLINICAL CANCER RESEARCH

Pathobiology of Helicobacter pylori–Induced Gastric Cancer

(2016) Manuel Amieva et al.   GASTROENTEROLOGY

Global patterns and trends in colorectal cancer incidence and mortality

(2016) Melina Arnold et al.   GUT

Quantitation of faecal Fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia

(2016) Sunny H Wong et al.   GUT

Biogeography of a human oral microbiome at the micron scale

(2016) Jessica L. Mark Welch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dancing with the Stars: How Choreographed Bacterial Interactions Dictate Nososymbiocity and Give Rise to Keystone Pathogens, Accessory Pathogens, and Pathobionts

(2016) George Hajishengallis et al.   TRENDS IN MICROBIOLOGY

Association ofFusobacterium nucleatumwith immunity and molecular alterations in colorectal cancer

(2016) Katsuhiko Nosho   WORLD JOURNAL OF GASTROENTEROLOGY

Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1

(2016) Marina Ayres Pereira et al.   PLoS Pathogens

Global burden of cancers attributable to infections in 2012: a synthetic analysis

(2016) Martyn Plummer et al.   Lancet Global Health

Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location

(2016) Kosuke Mima et al.   Clinical and Translational Gastroenterology

Cervical Microbiome and Cytokine Profile at Various Stages of Cervical Cancer: A Pilot Study

(2016) Astride Audirac-Chalifour et al.   PLoS One

Evaluation of antibody level against Fusobacterium nucleatum in the serological diagnosis of colorectal cancer

(2016) Hai-Fang Wang et al.   Scientific Reports

The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease

(2016) Tina J. Hieken et al.   Scientific Reports

C/EBP-β-activated microRNA-223 promotes tumour growth through targeting RASA1 in human colorectal cancer

(2015) D Sun et al.   BRITISH JOURNAL OF CANCER

Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

(2015) Ali Salanti et al.   CANCER CELL

Fusobacterium nucleatum: a commensal-turned pathogen

(2015) Yiping W Han   CURRENT OPINION IN MICROBIOLOGY

Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis

(2015) Kosuke Mima et al.   GUT

Colorectal cancer screening: a global overview of existing programmes

(2015) Eline H Schreuders et al.   GUT

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

Fap2 of Fusobacterium nucleatum Is a Galactose-Inhibitable Adhesin Involved in Coaggregation, Cell Adhesion, and Preterm Birth

(2015) S. Coppenhagen-Glazer et al.   INFECTION AND IMMUNITY

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis

(2015) Kei Mitsuhashi et al.   Oncotarget

Fusobacterium nucleatumand T Cells in Colorectal Carcinoma

(2015) Kosuke Mima et al.   JAMA Oncology

Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer

(2015) Christine Mehner et al.   Oncotarget

Helicobacter pylori CagA and Gastric Cancer: A Paradigm for Hit-and-Run Carcinogenesis

(2014) Masanori Hatakeyama   Cell Host & Microbe

BCG-induced trained immunity in NK cells: Role for non-specific protection to infection

(2014) Johanneke Kleinnijenhuis et al.   CLINICAL IMMUNOLOGY

Prevention of infective endocarditis: Guidelines from the American Heart Association

(2014) Walter Wilson et al.   JOURNAL OF THE AMERICAN DENTAL ASSOCIATION

Effects of tongue cleaning on bacterial flora in tongue coating and dental plaque: a crossover study

(2014) Miki Matsui et al.   BMC Oral Health

Oral Bacteria and Cancer

(2014) Sarah E. Whitmore et al.   PLoS Pathogens

Diagnostic Performance of Guaiac-Based Fecal Occult Blood Test in Routine Screening: State-Wide Analysis from Bavaria, Germany

(2013) Hermann Brenner et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Phase II feasibility study of preoperative chemotherapy with docetaxel, cisplatin, and fluorouracil for esophageal squamous cell carcinoma

(2013) Hiroki Hara et al.   CANCER SCIENCE

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

MicroRNA-31 Activates the RAS Pathway and Functions as an Oncogenic MicroRNA in Human Colorectal Cancer by Repressing RAS p21 GTPase Activating Protein 1 (RASA1)

(2013) Defang Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

Co-occurrence of anaerobic bacteria in colorectal carcinomas

(2013) René L Warren et al.   Microbiome

Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation

(2012) Robert R. Jenq et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Global burden of cancers attributable to infections in 2008: a review and synthetic analysis

(2012) Catherine de Martel et al.   LANCET ONCOLOGY

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

A bacterial driver–passenger model for colorectal cancer: beyond the usual suspects

(2012) Harold Tjalsma et al.   NATURE REVIEWS MICROBIOLOGY

Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

(2011) George Hajishengallis et al.   Cell Host & Microbe

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

(2011) M. Castellarin et al.   GENOME RESEARCH

Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

(2011) A. D. Kostic et al.   GENOME RESEARCH

Invasive potential of gut mucosa-derived fusobacterium nucleatum positively correlates with IBD status of the host

(2011) Jaclyn Strauss et al.   INFLAMMATORY BOWEL DISEASES

Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis

(2011) A. C. Goodwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fusobacterium nucleatum Outer Membrane Proteins Fap2 and RadD Induce Cell Death in Human Lymphocytes

(2010) C. W. Kaplan et al.   INFECTION AND IMMUNITY

Expression of CD176 (Thomsen-Friedenreich antigen) on lung, breast and liver cancer-initiating cells

(2010) Wei-Ming Lin et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Perspective: Alpha-Bugs, Their Microbial Partners, and the Link to Colon Cancer

(2010) Cynthia L. Sears et al.   JOURNAL OF INFECTIOUS DISEASES

Oral multispecies biofilm development and the key role of cell–cell distance

(2010) Paul E. Kolenbrander et al.   NATURE REVIEWS MICROBIOLOGY

A Novel Monoclonal Antibody Against DOG1 is a Sensitive and Specific Marker for Gastrointestinal Stromal Tumors

(2009) Inigo Espinosa et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

The Search for Infectious Causes of Human Cancers: Where and Why (Nobel Lecture)

(2009) Harald zur Hausen   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chronic Liver Disease Impairs Bacterial Clearance in a Human Model of Induced Bacteremia

(2009) Alix Ashare et al.   CTS-Clinical and Translational Science

TheFusobacterium nucleatumouter membrane protein RadD is an arginine-inhibitable adhesin required for inter-species adherence and the structured architecture of multispecies biofilm

(2008) Christopher W. Kaplan et al.   MOLECULAR MICROBIOLOGY