The onco-immunological implications of Fusobacterium nucleatum in breast cancer

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

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Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

(2020) Lishay Parhi et al.   Nature Communications

Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1

(2020) Youqiong Ye et al.   Genome Medicine

Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

(2019) Stephen S. Dominy et al.   Science Advances

The power of small changes: Comprehensive analyses of microbial dysbiosis in breast cancer

(2019) Sheetal Parida et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Association of breast and gut microbiota dysbiosis and the risk of breast cancer: a case-control clinical study

(2019) Julio Plaza-Díaz et al.   BMC CANCER

Role of Matrix Metalloproteinases in Angiogenesis and Cancer

(2019) Saray Quintero-Fabián et al.   Frontiers in Oncology

Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness

(2018) Edit Mikó et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Dental plaque-induced gingival conditions

(2018) Shinya Murakami et al.   JOURNAL OF PERIODONTOLOGY

Distinct Microbial Signatures Associated With Different Breast Cancer Types

(2018) Sagarika Banerjee et al.   Frontiers in Microbiology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors

(2018) Vladi Juric et al.   PLoS One

Periodontal Disease and Breast Cancer: A Meta-Analysis of 1,73,162 Participants

(2018) Jun Shao et al.   Frontiers in Oncology

Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21

(2017) Yongzhi Yang et al.   GASTROENTEROLOGY

Expression of checkpoint molecules on myeloid-derived suppressor cells

(2017) Marlene Ballbach et al.   IMMUNOLOGY LETTERS

The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200

(2017) Muhammad Zaeem Noman et al.   OncoImmunology

A comprehensive analysis of breast cancer microbiota and host gene expression

(2017) Kevin J. Thompson et al.   PLoS One

The Microbiota of Breast Tissue and Its Association with Breast Cancer

(2016) Camilla Urbaniak et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Research progress of hydroxychloroquine and autophagy inhibitors on cancer

(2016) Ting-Ting Shi et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc

(2016) Jawad Abed et al.   Cell Host & Microbe

Chemoattractant Receptors BLT1 and CXCR3 Regulate Antitumor Immunity by Facilitating CD8+T Cell Migration into Tumors

(2016) Zinal S. Chheda et al.   JOURNAL OF IMMUNOLOGY

MYC regulates the antitumor immune response through CD47 and PD-L1

(2016) S. C. Casey et al.   SCIENCE

Presence of Porphyromonas gingivalis in esophagus and its association with the clinicopathological characteristics and survival in patients with esophageal cancer

(2016) Shegan Gao et al.   Infectious Agents and Cancer

The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease

(2016) Tina J. Hieken et al.   Scientific Reports

Periodontal Disease and Breast Cancer: Prospective Cohort Study of Postmenopausal Women

(2015) J. L. Freudenheim et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Fusobacterium nucleatum: a commensal-turned pathogen

(2015) Yiping W Han   CURRENT OPINION IN MICROBIOLOGY

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

Investigation of the Association Between the Fecal Microbiota and Breast Cancer in Postmenopausal Women: a Population-Based Case-Control Pilot Study

(2015) James J. Goedert et al.   JNCI-Journal of the National Cancer Institute

Fusobacterium nucleatum, inflammation, and immunity: the fire within human gut

(2015) Arif Bashir et al.   TUMOR BIOLOGY

Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints

(2015) M. E. Mikucki et al.   Nature Communications

Investigation of the Association Between the Fecal Microbiota and Breast Cancer in Postmenopausal Women: a Population-Based Case-Control Pilot Study

(2015) James J. Goedert et al.   JNCI-Journal of the National Cancer Institute

P. gingivalis in Periodontal Disease and Atherosclerosis – Scenes of Action for Antimicrobial Peptides and Complement

(2015) Mehak Hussain et al.   Frontiers in Immunology

Fusobacterium nucleatumand T Cells in Colorectal Carcinoma

(2015) Kosuke Mima et al.   JAMA Oncology

Microbiota of Human Breast Tissue

(2014) Camilla Urbaniak et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Paclitaxel Therapy Promotes Breast Cancer Metastasis in a TLR4-Dependent Manner

(2014) L. Volk-Draper et al.   CANCER RESEARCH

Microbial Dysbiosis Is Associated with Human Breast Cancer

(2014) Caiyun Xuan et al.   PLoS One

NF- B, an Active Player in Human Cancers

(2014) Y. Xia et al.   Cancer Immunology Research

Toll-Like Receptors and Prostate Cancer

(2014) Shu Zhao et al.   Frontiers in Immunology

Oral Porphyromonas gingivalis translocates to the liver and regulates hepatic glycogen synthesis through the Akt/GSK-3β signaling pathway

(2013) Makoto Ishikawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Role of Toll-like receptors in microbiota-associated gastrointestinal cancer metastasis

(2013) Hao Ding et al.   Journal of Cancer Research and Therapeutics

TLR4 Is a Novel Determinant of the Response to Paclitaxel in Breast Cancer

(2013) S. Rajput et al.   MOLECULAR CANCER THERAPEUTICS

Myeloid-Derived Suppressor Cells and anti-tumor T cells: a complex relationship

(2012) Ngozi R. Monu et al.   IMMUNOLOGICAL INVESTIGATIONS

Fusobacterium nucleatum Outer Membrane Proteins Fap2 and RadD Induce Cell Death in Human Lymphocytes

(2010) C. W. Kaplan et al.   INFECTION AND IMMUNITY

Rheumatoid arthritis and periodontal disease

(2010) Jean-Marie Berthelot et al.   JOINT BONE SPINE

Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine

(2009) M. K. Srivastava et al.   CANCER RESEARCH

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

(2009) Siddhartha Jaiswal et al.   CELL

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

(2009) Ravindra Majeti et al.   CELL

A Systems Perspective of Ras Signaling in Cancer

(2009) E. C. Stites et al.   CLINICAL CANCER RESEARCH

Microbiology of Odontogenic Bacteremia: beyond Endocarditis

(2009) N. B. Parahitiyawa et al.   CLINICAL MICROBIOLOGY REVIEWS

Decreased Expression of the RAS-GTPase Activating Protein RASAL1 Is Associated With Colorectal Tumor Progression

(2008) Miki Ohta et al.   GASTROENTEROLOGY