Bladder Cancer Immunotherapy by BCG Is Associated with a Significantly Reduced Risk of Alzheimer’s Disease and Parkinson’s Disease

Restoring metabolism of myeloid cells reverses cognitive decline in ageing

(2021) Paras S. Minhas et al.   NATURE

Four distinct trajectories of tau deposition identified in Alzheimer’s disease

(2021) Jacob W. Vogel et al.   NATURE MEDICINE

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease

(2020) David Gate et al.   NATURE

BCG: a vaccine with multiple faces

(2020) Marco Antonio Yamazaki-Nakashimada et al.   Human Vaccines & Immunotherapeutics

SARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults

(2020) Uri Hamiel et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Parkinson disease and the immune system — associations, mechanisms and therapeutics

(2020) Eng-King Tan et al.   Nature Reviews Neurology

BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment

(2020) Branko Cirovic et al.   Cell Host & Microbe

Significantly Improved COVID-19 Outcomes in Countries with Higher BCG Vaccination Coverage: A Multivariable Analysis

(2020) Danielle Klinger et al.   Vaccines

Mechanisms of BCG in the treatment of bladder cancer-current understanding and the prospect

(2020) Jiansong Han et al.   BIOMEDICINE & PHARMACOTHERAPY

Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly

(2020) Evangelos J. Giamarellos-Bourboulis et al.   CELL

Repositioning of Immunomodulators: A Ray of Hope for Alzheimer’s Disease?

(2020) Antonio Munafò et al.   Frontiers in Neuroscience

Treatment of Alzheimer’s Disease and Blood–Brain Barrier Drug Delivery

(2020) William M. Pardridge   Pharmaceuticals

Bacillus Calmette–Guérin treatment of bladder cancer

(2019) Neelam Mukherjee et al.   CURRENT OPINION IN UROLOGY

Non-specific effects of BCG vaccine on viral infections

(2019) S.J.C.F.M. Moorlag et al.   CLINICAL MICROBIOLOGY AND INFECTION

Bacillus Calmette-Guérin (BCG) therapy lowers the incidence of Alzheimer’s disease in bladder cancer patients

(2019) Ofer N. Gofrit et al.   PLoS One

Understanding the impact of sex and gender in Alzheimer's disease: A call to action

(2018) Rebecca A. Nebel et al.   Alzheimers & Dementia

APOE and Alzheimer’s Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer’s Pathogenesis

(2018) Md. Sahab Uddin et al.   MOLECULAR NEUROBIOLOGY

Sex differences in Alzheimer disease — the gateway to precision medicine

(2018) Maria Teresa Ferretti et al.   Nature Reviews Neurology

Mechanisms of BCG immunotherapy and its outlook for bladder cancer

(2018) Caroline Pettenati et al.   Nature Reviews Urology

Low-dose IL-2 expands CD4+ regulatory T cells with a suppressive function in vitro via the STAT5-dependent pathway in patients with chronic kidney diseases

(2018) Yuanyuan Li et al.   RENAL FAILURE

Long-term reduction in hyperglycemia in advanced type 1 diabetes: the value of induced aerobic glycolysis with BCG vaccinations

(2018) Willem M. Kühtreiber et al.   npj Vaccines

Cancer and dementia: Two sides of the same coin?

(2018) Kimberly D. van der Willik et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Prevalence and comorbidities of dementia in Israel: A nationally representative cohort study

(2018) A. Kodesh   INTERNATIONAL PSYCHOGERIATRICS

Combined effect of BCG vaccination and enriched environment promote neurogenesis and spatial cognition via a shift in meningeal macrophage M2 polarization

(2017) Fangfang Qi et al.   Journal of Neuroinflammation

A systemic view of Alzheimer disease — insights from amyloid-β metabolism beyond the brain

(2017) Jun Wang et al.   Nature Reviews Neurology

Prevalencia e incidencia de la enfermedad de Alzheimer en Europa: metaanálisis

(2017) H. Niu et al.   NEUROLOGIA

Pathology of Neurodegenerative Diseases

(2017) Brittany N. Dugger et al.   Cold Spring Harbor Perspectives in Biology

What Have We Learnt about BCG Vaccination in the Last 20 Years?

(2017) Hazel M. Dockrell et al.   Frontiers in Immunology

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Is Cancer Protective for Subsequent Alzheimer’s Disease Risk? Evidence From the Utah Population Database

(2016) Heidi A. Hanson et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

Duration of BCG protection against tuberculosis and change in effectiveness with time since vaccination in Norway: a retrospective population-based cohort study

(2016) Patrick Nguipdop-Djomo et al.   LANCET INFECTIOUS DISEASES

Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer’s disease model

(2016) Hyunjung Baek et al.   Oncotarget

Immunometabolic Pathways in BCG-Induced Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Reports

Associations between cancer and Alzheimer's disease in a U.S. Medicare population

(2016) Daryl Michal Freedman et al.   Cancer Medicine

Trained innate immunity as underlying mechanism for the long-term, nonspecific effects of vaccines

(2015) Bastiaan A. Blok et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Role of the innate and adaptive immune responses in the course of multiple sclerosis

(2015) Bernhard Hemmer et al.   LANCET NEUROLOGY

MDS clinical diagnostic criteria for Parkinson's disease

(2015) Ronald B. Postuma et al.   MOVEMENT DISORDERS

Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations

(2015) Abdallah M. Abdallah et al.   Scientific Reports

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

BCG-induced trained immunity in NK cells: Role for non-specific protection to infection

(2014) Johanneke Kleinnijenhuis et al.   CLINICAL IMMUNOLOGY

Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials

(2013) Punam Mangtani et al.   CLINICAL INFECTIOUS DISEASES

Maintenance Bacillus Calmette-Guérin Treatment of Non–muscle-invasive Bladder Cancer: A Critical Evaluation of the Evidence

(2013) Behfar Ehdaie et al.   EUROPEAN UROLOGY

Bacillus Calmette-Guerin vaccine-mediated neuroprotection is associated with regulatory T-cell induction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

(2013) Goran Laćan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effects of Bacille Calmette-Guerin after the first demyelinating event in the CNS

(2013) G. Ristori et al.   NEUROLOGY

Epidemiology and Risk Factors of Urothelial Bladder Cancer

(2012) Maximilian Burger et al.   EUROPEAN UROLOGY

Greater cognitive deterioration in women than men with Alzheimer's disease: A meta analysis

(2012) Karen Irvine et al.   JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY

A Human Challenge Model for Mycobacterium tuberculosis Using Mycobacterium bovis Bacille Calmette-Guérin

(2012) Angela M. Minassian et al.   JOURNAL OF INFECTIOUS DISEASES

The influence of BCG vaccine strain on mycobacteria-specific and non-specific immune responses in a prospective cohort of infants in Uganda

(2012) Elizabeth J. Anderson et al.   VACCINE

Current and future treatments for Alzheimer’s disease

(2012) Konstantina G. Yiannopoulou et al.   Therapeutic Advances in Neurological Disorders

Randomized Trial of BCG Vaccination at Birth to Low-Birth-Weight Children: Beneficial Nonspecific Effects in the Neonatal Period?

(2011) Peter Aaby et al.   JOURNAL OF INFECTIOUS DISEASES

Bacillus Calmette-Guérin treatment of non-muscle invasive bladder cancer

(2010) Richard J Sylvester   INTERNATIONAL JOURNAL OF UROLOGY

Genetic aspects of Alzheimer disease

(2008) Thomas D Bird   GENETICS IN MEDICINE