Fusobacterium nucleatum supresses anti-tumor immunity by activating CEACAM1

The Helicobacter pylori HopQ outermembrane protein inhibits immune cell activities

(2019) Chamutal Gur et al.   OncoImmunology

Abnormal expression of circulating and tumor-infiltrating carcinoembryonic antigen-related cell adhesion molecule 1 in patients with glioma

(2018) Jinhu Li et al.   Oncology Letters

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection

(2018) Vishal Khairnar et al.   Nature Communications

Expression of CEACAM1 or CEACAM5 in AZ-521 cells restores the type IV secretion deficiency for translocation of CagA by Helicobacter pylori

(2018) Nicole Tegtmeyer et al.   CELLULAR MICROBIOLOGY

Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21

(2017) Yongzhi Yang et al.   GASTROENTEROLOGY

Co-expression of TIM-3 and CEACAM1 promotes T cell exhaustion in colorectal cancer patients

(2017) Yang Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Analysis ofFusobacteriumpersistence and antibiotic response in colorectal cancer

(2017) Susan Bullman et al.   SCIENCE

HCMV vCXCL1 Binds Several Chemokine Receptors and Preferentially Attracts Neutrophils over NK Cells by Interacting with CXCR2

(2016) Rachel Yamin et al.   Cell Reports

Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs

(2016) Anahita Javaheri et al.   Nature Microbiology

Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA

(2016) Verena Königer et al.   Nature Microbiology

Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis

(2015) Kosuke Mima et al.   GUT

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

Neutrophils Infiltration in the Tongue Squamous Cell Carcinoma and Its Correlation with CEACAM1 Expression on Tumor Cells

(2014) Ning Wang et al.   PLoS One

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer

(2012) A Arabzadeh et al.   ONCOGENE

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

(2011) M. Castellarin et al.   GENOME RESEARCH

Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

(2011) A. D. Kostic et al.   GENOME RESEARCH

The activating receptor NKp46 is essential for the development of type 1 diabetes

(2009) Chamutal Gur et al.   NATURE IMMUNOLOGY

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

(2009) N. Stanietsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA