Fluorofenidone Inhibits UUO/IRI-Induced Renal Fibrosis by Reducing Mitochondrial Damage

Redox signaling pathways in unilateral ureteral obstruction (UUO)-induced renal fibrosis

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Axl‐inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model

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Dysfunction in Mitochondrial Electron Transport Chain Complex I, Pyruvate Dehydrogenase Activity, and Mutations in ND1 and ND4 Gene in Autism Spectrum Disorder Subjects from Tamil Nadu Population, India

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Targeting of intragraft reactive oxygen species by APP‐103, a novel polymer product, mitigates ischemia/reperfusion injury and promotes the survival of renal transplants

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Targeting the progression of chronic kidney disease

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Reactive Oxygen Species and Redox Signaling in Chronic Kidney Disease

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Alleviation of TGF‐β1 induced tubular epithelial–mesenchymal transition via the δ‐opioid receptor

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Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration

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Mitochondrial dysfunction and endoplasmic reticulum stress in the promotion of fibrosis in obstructive nephropathy induced by unilateral ureteral obstruction

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Fluorofenidone attenuates renal fibrosis by inhibiting the mtROS-NLRP3 pathway in a murine model of folic acid nephropathy

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Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation

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Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway

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Therapeutic Approaches in Mitochondrial Dysfunction, Inflammation, and Autophagy in Uremic Cachexia: Role of Aerobic Exercise

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Ellagic Acid Ameliorates Renal Ischemic-Reperfusion Injury Through NOX4/JAK/STAT Signaling Pathway

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Fluorofenidone protects against acute kidney injury

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The preventive and therapeutic implication for renal fibrosis by targetting TGF-β/Smad3 signaling

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PGC-1: The Energetic Regulator in Cardiac Metabolism

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Hypochlorite modified albumins promote cell death in the tubule interstitium in rats via mitochondrial damage in obstructive nephropathy and the protective effects of antioxidant peptides

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Sirtuins in Renal Health and Disease

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Mitochondria as a therapeutic target for common pathologies

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Salidroside stimulates the Sirt1/PGC-1α axis and ameliorates diabetic nephropathy in mice

(2018) Haiyan Xue et al.   PHYTOMEDICINE

Mitochondrial energetics in the kidney

(2017) Pallavi Bhargava et al.   Nature Reviews Nephrology

CD36 in chronic kidney disease: novel insights and therapeutic opportunities

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Postconditioning protects renal fibrosis by attenuating oxidative stress-induced mitochondrial injury

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Mitochondrial ROS control of cancer

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Mefunidone ameliorates renal inflammation and tubulointerstitial fibrosis via suppression of IKKβ phosphorylation

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Fluorofenidone attenuates pulmonary inflammation and fibrosisviainhibiting the activation of NALP3 inflammasome and IL-1β/IL-1R1/MyD88/NF-κB pathway

(2016) Cheng Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TGF-β: the master regulator of fibrosis

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The Protective Mechanism of Fluorofenidone in Renal Interstitial Inflammation and Fibrosis

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Paradigm Shifts in Atherosclerotic Renovascular Disease: Where Are We Now?

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Fluorofenidone attenuates hepatic fibrosis by suppressing the proliferation and activation of hepatic stellate cells

(2013) Yu Peng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Autophagy and apoptosis in tubular cells following unilateral ureteral obstruction are associated with mitochondrial oxidative stress

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Fluorofenidone attenuates renal interstitial fibrosis in the rat model of obstructive nephropathy

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Fluorofenidone Attenuates Diabetic Nephropathy and Kidney Fibrosis in db/db Mice

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How mitochondria produce reactive oxygen species

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