Therapeutic targeting of BAP1/ASXL3 sub-complex in ASCL1-dependent small cell lung cancer

Small-cell lung cancer

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BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation

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BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation

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Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo

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Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis

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BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression

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BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5

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Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1–BAP1 complex

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Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis

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Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

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Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas

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The Deubiquitinating Enzyme BAP1 Regulates Cell Growth via Interaction with HCF-1

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