The tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism

Indirect Routes to Aminoacyl-tRNA: The Diversity of Prokaryotic Cysteine Encoding Systems

(2022) Takahito Mukai et al.   Frontiers in Genetics

Genetic Encoding of Three Distinct Noncanonical Amino Acids Using Reprogrammed Initiator and Nonsense Codons

(2021) Jeffery M. Tharp et al.   ACS Chemical Biology

Genetic Incorporation of ϵ‐ N ‐Benzoyllysine by Engineering Methanomethylophilus alvus Pyrrolysyl‐tRNA Synthetase

(2021) Li Cao et al.   CHEMBIOCHEM

A Genetically Encoded Fluorosulfonyloxybenzoyl-l-lysine for Expansive Covalent Bonding of Proteins via SuFEx Chemistry

(2021) Jun Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bacterial translation machinery for deliberate mistranslation of the genetic code

(2021) Oscar Vargas-Rodriguez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A standardized archaeal taxonomy for the Genome Taxonomy Database

(2021) Christian Rinke et al.   Nature Microbiology

A catalogue of 1,167 genomes from the human gut archaeome

(2021) Cynthia Maria Chibani et al.   Nature Microbiology

IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era

(2020) Bui Quang Minh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids

(2020) Daniel L. Dunkelmann et al.   Nature Chemistry

Fully Productive Cell-Free Genetic Code Expansion by Structure-Based Engineering of Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase

(2020) Eiko Seki et al.   ACS Synthetic Biology

Reprogramming the genetic code

(2020) Daniel de la Torre et al.   NATURE REVIEWS GENETICS

Reply to ‘Evolutionary placement of Methanonatronarchaeia’

(2019) Dimitry Y. Sorokin et al.   Nature Microbiology

Evolutionary placement of Methanonatronarchaeia

(2019) Monique Aouad et al.   Nature Microbiology

Towards functional characterization of archaeal genomic dark matter

(2019) Kira S. Makarova et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Methanonatronarchaeum thermophilum gen. nov., sp. nov. and 'Candidatus Methanohalarchaeum thermophilum', extremely halo(natrono)philic methyl-reducing methanogens from hypersaline lakes comprising a new euryarchaeal class Methanonatronarchaeia classis nov.

(2018) Dimitry Y. Sorokin et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs

(2018) Julian C. W. Willis et al.   Nature Chemistry

Methanomethylophilus alvus Mx1201 provides basis for mutual orthogonal pyrrolysyl tRNA/aminoacyl-tRNA synthetase pairs in mammalian cells.

(2018) Birthe Meineke et al.   ACS Chemical Biology

An Evolved Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase/tRNA Pair Is Highly Active and Orthogonal in Mammalian Cells

(2018) Václav Beránek et al.   BIOCHEMISTRY

Engineering an Automaturing Transglutaminase with Enhanced Thermostability by Genetic Code Expansion with Two Codon Reassignments

(2018) Kazumasa Ohtake et al.   ACS Synthetic Biology

Enhancing Protein Stability with Genetically Encoded Noncanonical Amino Acids

(2018) Jack C. Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Versatility of Synthetic tRNAs in Genetic Code Expansion

(2018) Kyle Hoffman et al.   Genes

Digging More Missing Proteins Using an Enrichment Approach with ProteoMiner

(2017) Siqi Li et al.   JOURNAL OF PROTEOME RESEARCH

Single-cell genomics reveals pyrrolysine-encoding potential in members of uncultivated archaeal candidate division MSBL1

(2017) Yue Guan et al.   Environmental Microbiology Reports

Methionine Sulfoxide Reductase A (MsrA) and Its Function in Ubiquitin-Like Protein Modification in Archaea

(2017) Xian Fu et al.   mBio

RNA-Dependent Cysteine Biosynthesis in Bacteria and Archaea

(2017) Takahito Mukai et al.   mBio

Discovery of extremely halophilic, methyl-reducing euryarchaea provides insights into the evolutionary origin of methanogenesis

(2017) Dimitry Y. Sorokin et al.   Nature Microbiology

Pyrrolysyl-tRNA Synthetase, an Aminoacyl-tRNA Synthetase for Genetic Code Expansion

(2016) Ana Crnković et al.   CROATICA CHEMICA ACTA

Methanogenesis and the Wood–Ljungdahl Pathway: An Ancient, Versatile, and Fragile Association

(2016) Guillaume Borrel et al.   Genome Biology and Evolution

A chemical biology route to site-specific authentic protein modifications

(2016) A. Yang et al.   SCIENCE

Ubiquitin-Like Proteasome System Represents a Eukaryotic-Like Pathway for Targeted Proteolysis in Archaea

(2016) Xian Fu et al.   mBio

Saturation of recognition elements blocks evolution of new tRNA identities

(2016) A. Saint-Leger et al.   Science Advances

Archaeal Inorganic Pyrophosphatase Displays Robust Activity under High-Salt Conditions and in Organic Solvents

(2015) Lana J. McMillan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Halophiles and their enzymes: negativity put to good use

(2015) Shiladitya DasSarma et al.   CURRENT OPINION IN MICROBIOLOGY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Exploring the potential impact of an expanded genetic code on protein function

(2015) Han Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonsense suppression in archaea

(2015) Arpita Bhattacharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expanding and Reprogramming the Genetic Code of Cells and Animals

(2014) Jason W. Chin   Annual Review of Biochemistry

Pyrrolysyl-tRNA synthetase: An ordinary enzyme but an outstanding genetic code expansion tool

(2014) Wei Wan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins

(2014) Kathrin Lang et al.   CHEMICAL REVIEWS

Polyspecific pyrrolysyl-tRNA synthetases from directed evolution

(2014) Li-Tao Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Characteristics of the Pyrrolysine System in the 7th Order of Methanogens: Implications for the Evolution of a Genetic Code Expansion Cassette

(2014) Guillaume Borrel et al.   ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL

Upgrading protein synthesis for synthetic biology

(2013) Patrick O'Donoghue et al.   Nature Chemical Biology

Functional context, biosynthesis, and genetic encoding of pyrrolysine

(2011) Marsha A Gaston et al.   CURRENT OPINION IN MICROBIOLOGY

Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface

(2011) Alessandro Siglioccolo et al.   BMC STRUCTURAL BIOLOGY

A Facile System for Genetic Incorporation of Two Different Noncanonical Amino Acids into One Protein inEscherichia coli

(2010) Wei Wan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Complete Genome Sequence of Haloferax volcanii DS2, a Model Archaeon

(2010) Amber L. Hartman et al.   PLoS One

Pyrrolysyl-tRNA synthetase–tRNAPyl structure reveals the molecular basis of orthogonality

(2009) Kayo Nozawa et al.   NATURE